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Gastroenterology news

GLP-1 agonist drugs show digestive side effects but may help fight infections

Originally developed to treat diabetes, a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now stepping into the spotlight as weight loss drugs. A recent umbrella review draws attention to ...

New mouse model of virus-driven liver cancer may boost diagnosis and treatments

Liver cancer is one of the world's deadliest cancers, and most cases are linked to chronic viral hepatitis. Yet scientists have lacked an animal model that faithfully recapitulates how the disease unfolds in people, from ...

Scientists target key protein duo driving colon, liver cancer

Cedars-Sinai Health Sciences University investigators have identified a drug-like compound that prevents two proteins from working together to promote the growth of colorectal and liver cancer. Findings from the preclinical ...

How pancreatic tumors thwart an iron-driven demise

Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...

Liver cancer prevention, treatment efforts are working

Prevention and treatment advances are reducing the number of new liver cancer patients and narrowing survival gaps among racial groups, a Cedars-Sinai Cancer study published in the journal Clinical Gastroenterology and Hepatology ...

Good sleep starts in the gut

You might think good sleep happens in your brain, but restorative sleep actually begins much lower in the body: in the gut.

Fibulin-5: A potential marker for liver fibrosis detection

When damage to the liver caused by alcohol or viral infections persists, liver fibrosis progresses and replaces tissue with collagen fibers. This is especially a risk in chronic hepatitis C patients, where liver fibrosis ...

Why important genes 'go quiet' as we get older

The human gut renews itself faster than any other tissue: every few days, new cells are created from specialized stem cells. However, as we get older, epigenetic changes build up in these stem cells. These are chemical markers ...