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Gastroenterology news

New approach opens rare immune cells to genetic risk research

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA ...

A new target in the gut for reducing Alzheimer's risk

A compound produced by bacteria in many people's digestive tracts increases the risk of developing Alzheimer's disease and speeds cognitive decline in dementia patients, making it a potential target for a treatment that could ...

Patients with IBD face elevated risk of psychiatric disorders

Patients with inflammatory bowel disease (IBD) face a significantly higher risk of psychiatric disorders starting two to three years before diagnosis and lasting up to a decade afterward, according to a nationwide study published ...

Scientists target key protein duo driving colon, liver cancer

Cedars-Sinai Health Sciences University investigators have identified a drug-like compound that prevents two proteins from working together to promote the growth of colorectal and liver cancer. Findings from the preclinical ...

How pancreatic tumors thwart an iron-driven demise

Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...