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Gastroenterology news

New approach opens rare immune cells to genetic risk research

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA ...

A new target in the gut for reducing Alzheimer's risk

A compound produced by bacteria in many people's digestive tracts increases the risk of developing Alzheimer's disease and speeds cognitive decline in dementia patients, making it a potential target for a treatment that could ...

Patients with IBD face elevated risk of psychiatric disorders

Patients with inflammatory bowel disease (IBD) face a significantly higher risk of psychiatric disorders starting two to three years before diagnosis and lasting up to a decade afterward, according to a nationwide study published ...

New approach to gene correction for iron storage disease

Hereditary primary hemochromatosis is caused by a single faulty building block in a gene. This leads to iron overload, which can have serious consequences for organs and joints. In preclinical studies, researchers have already ...

Key gut protein balances immune protection and tolerance

A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators. The discovery illuminates ...

How immune cells in our gut mesentery fight salmonella

Widely recognized as the face of food poisoning, salmonella bacteria lurk in raw meat and poultry, on pets, and in unpasteurized dairy products. If untreated, extreme cases can lead to full-body infections, like typhoid fever. ...

Study reveals a distinct subtype of eosinophilic esophagitis

Researchers from Ann & Robert H. Lurie Children's Hospital of Chicago identified a distinct subtype of eosinophilic esophagitis (EoE)—a chronic allergic inflammatory disorder in which the esophagus narrows, interfering with ...

New biological clues behind coffee's benefit to liver health

In one of the most comprehensive studies of coffee and liver health to date, Cedars-Sinai Health Sciences University investigators linked higher coffee consumption with a lower risk of cirrhosis, liver cancer and liver-related ...