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Gastroenterology news

FDA-approved drug may reverse T-cell exclusion in fibrolamellar liver cancer

Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal liver cancer, but a new study finds an existing FDA-approved drug may allow the immunotherapy ...

Why are more under-50s getting colorectal cancer? 'We don't know'

The death of US actor James Van Der Beek was just the latest reminder that colorectal cancer has been surging among people under 50 in recent years—and no one knows why.

Studies show 11 genetic variants affect gut microbiome

In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do there. Only two genetic ...

NSMF protein identified as key regulator in colorectal cancer

A research team affiliated with UNIST has unveiled a novel approach to halt the progression of colorectal cancer by inducing irreversible cellular aging. Their findings demonstrate that suppressing a neural protein called ...

Cholesterol crystals may trigger some liver disease

Cholesterol crystals in the liver may stiffen the organ early in those with metabolic dysfunction-associated steatotic liver disease (MASLD)—well before scarring develops—according to new research from a team in the Perelman ...

Pancreatic cancer: Warning signs to heed

Your pancreas has important jobs to do. A large gland behind the lower part of the stomach, it produces hormones that regulate blood sugar and enzymes that help digest food. What if it develops cancer?

Scientists create 'smart underwear' to measure human flatulence

Scientists at the University of Maryland have created Smart Underwear, the first wearable device designed to measure human flatulence. By tracking hydrogen in flatus, the device helps scientists revisit long-standing assumptions ...

Researchers develop a new model to study colorectal cancer

Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients. ...

Fighting Crohn's with algae—can it heal the gut?

The first week of December marks Crohn's & Colitis Awareness Week. Since 1990, cases of inflammatory bowel disease (IBD) have nearly doubled. It has risen fastest among those aged 15–39. IBD is a chronic inflammation of ...

Alternative sweetener sorbitol linked to liver disease

Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), or sugar alcohols are often seen as healthier alternatives to food with refined sugar (glucose). But that assumption is being challenged with new ...

Gut microbes may have links with sleep deprivation

Sleep is one of the essential physiological needs for human survival, alongside food, water and air. But sleep is socially driven, influenced by environmental and personal factors, and a recent study suggests it may be affected ...

Pattern of chronic rejection for liver transplants decoded

Liver transplants often save the lives of seriously ill patients. However, there remains a risk that the body will reject the new organ. Doctors distinguish between acute and chronic rejection. While acute rejection is easy ...