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Genetics
A new paper in the Journal of Neuropathology & Experimental Neurology finds a gene that may help explain a large part of the genetic risk for developing Alzheimer disease.
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An international, multidisciplinary research team from more than 50 institutions, led by geneticist and psychiatrist Gholson Lyon, MD, Ph.D., of the New York State Office for People With Developmental Disabilities' (OPWDD) ...
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Researchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darrin Bann, an otolaryngology resident at the College of Medicine and lead author of the ...
18 hours ago
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When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play ...
18 hours ago
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Officials from Vertex Pharmaceuticals and CRISPR Therapeutics have announced that preliminary results from testing CRISPR gene-editing treatment in human patients with blood disorders show promise thus far. The joint project ...
A new study from Uppsala University shows that whole-genome sequencing increases the precision of genetic studies, which in turn can improve our understanding of how to use biomarkers to discover disease. The results are ...
21 hours ago
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Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.
Nov 19, 2019
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It is generally known that viruses, with their cell-invading capabilities, can be responsible for a number of different cancers. What is less broadly discussed are the cancer-causing capabilities of bacteria, or the processes ...
Nov 18, 2019
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Living implies change. This is what happens to the cells of our bodies as we grow older: They accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain ...
Nov 18, 2019
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Scientists at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed new delivery vehicles for future gene therapies. A team of researchers led by Dr. Christian Wölk are using artificial ...
Nov 18, 2019
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Genetic studies spanning three generations of a Persian Jewish family by researchers at Ben-Gurion University of the Negev (BGU) have identified a gene that causes nighttime atrial fibrillation (AFib).
Nov 18, 2019
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Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of ...
Nov 15, 2019
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Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.
Nov 15, 2019
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Researchers from the Universities of Cardiff and Bristol have devised a test that could in future help to identify children at risk of developing a very common eye condition.
Nov 15, 2019
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Following a nearly 25-year search across three continents, parents of a pair of sisters—who as children slowly became paralyzed from the waist down—finally have a diagnosis, according to researchers at University of Southern ...
Nov 15, 2019
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One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA—alterations in coding regions of the genome that can lead directly to changes in the expression of particular ...
Nov 15, 2019
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AstraZeneca and MSD (Merck) announced today that the U.S. Food and Drug Administration (FDA) has granted acceptance to file status of its application for the MEK inhibitor selumetinib, for use in patients with plexiform neurofibromas, ...
Nov 14, 2019
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From organisms as simple as worms to those as complex as humans, sleep is a fundamental necessity. But although an estimated 50 to 70 million people in the United States suffer from a chronic sleep disorder, the genetic mechanisms ...
Nov 14, 2019
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In the last decade, genome sequencing has provided many people with a wealth of information about risks for certain diseases.
Nov 13, 2019
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In the past week, news has spread of a Florida judge's decision to grant a warrant allowing police to search one of the world's largest online DNA databases, for leads in a criminal case.
Nov 13, 2019
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