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Genetics news

Genetics

Key gene identified for improving multiple sclerosis treatment

The disease multiple sclerosis (MS) attacks the central nervous system and, with time, can give rise to muscle tremors and loss of balance. Researchers at Karolinska Institutet have now identified a gene, Gsta4, that protects ...

Genetics

Engineered capsids for efficient gene delivery to the eye

A rational design approach created novel variants of adeno-associated viral (AAV) capsids. These have improved transduction properties in the mouse retina and cornea. as reported in the peer-reviewed journal Human Gene Therapy.

Medical research

New type of taste cell discovered in taste buds

Our mouths may be home to a newly discovered set of multi-tasking taste cells that—unlike most known taste cells, which detect individual tastes—are capable of detecting sour, sweet, bitter and umami stimuli. A research ...

Genetics

Gene therapy targets inner retina to combat blindness

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease. Adeno-associated viral (AAV)-mediated expression of the human CLN3 gene led to significant survival ...

Oncology & Cancer

HPV strains may impact cervical cancer prognosis

An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumors caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics ...

Genetics

Novel approach reduces SCA1 symptoms in animal model

Research has shown that a mutation in the ATAXIN-1 gene leads to accumulation of Ataxin-1 (ATXN1) protein in brain cells and is the root cause of a rare genetic neurodegenerative disease known as spinocerebellar ataxia type ...

Medical research

Genetic cause of congenital malformation discovered

Spontaneous mutations of a single gene are likely to cause serious developmental disorders of the excretory organs and genitalia. This is shown in an international study led by the University of Bonn and published in the ...

Genetics

Autism: How a gene alteration modifies social behavior

A team of researchers at the Biozentrum, University of Basel, has discovered a new connection between a genetic alteration and social difficulties related to autism: A mutation in the neuroligin-3 gene reduces the effect ...

Genetics

Discovery shows promise for treating Huntington's disease

Huntington's disease is a progressive and aggressively debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition. It is caused by a mutation in the gene that encodes the ...