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Genetics news
Genetics
Inhibiting enzyme could halt cell death in Parkinson's disease, study finds
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.
8 hours ago
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Genetics
Virtual reality software uncovers new details in pediatric heart tumors
New cutting-edge software developed in Melbourne can help uncover how the most common heart tumor in children forms and changes. And the technology has the potential to further our understanding of other childhood diseases, ...
4 hours ago
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New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects
For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.
17 hours ago
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New potential drug targets for multiple sclerosis identified
A new study by researchers in the Department of Clinical Neuroscience, Karolinska Institutet, has identified 18 potential drug targets for the treatment of multiple sclerosis. The study may pave the way for new treatment ...
9 hours ago
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Understanding the role of pigmentation in hereditary hearing loss
Melanin can either protect or worsen hereditary hearing loss depending on genetic context, as reported by researchers from Japan. Using genetically engineered mice lacking the SLC26A4 gene, the researchers found that problems ...
6 hours ago
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Gene signature of hepatic ferroptosis reveals its pathogenic features
By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an integrated gene signature for ferroptosis. They evaluated the associated genes in both mice and human ...
6 hours ago
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Trauma is carried in your DNA. But science reveals a more complicated story
As war continues to rage in Gaza and Ukraine, there is concern about how the related trauma might be transmitted to future generations of people in those regions.
11 hours ago
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Dysregulated epigenetic memory in early embryos offers new clues to the inheritance of polycystic ovary syndrome
Novel research presented at the 41st annual meeting of the European Society of Human Reproduction and Embryology (ESHRE) has found that embryos from women with PCOS carry a distinctive "epigenetic memory" that could explain ...
12 hours ago
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Genetic ancestry linked to risk of severe dengue
For the first time, the extreme variability in dengue fever has been linked to a biological mechanism, potentially opening doors to new treatments and vaccines for the most common mosquito-borne disease worldwide.
Jun 30, 2025
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A new model enables drug discovery for a disorder affecting 40 people worldwide
Researchers at the Gray Faculty of Medical and Health Sciences at Tel Aviv University have developed a model that accurately replicates an extremely rare and sometimes fatal genetic disorder caused by a mutation in the GRIN2D ...
Jun 30, 2025
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Genes can reveal if anxiety medicine will help or not
Depression and anxiety are the most common psychiatric disorders in the world. Around 300 million people suffer from depression, whereas 301 million have anxiety disorder. That's nearly 8% of the global population. Unfortunately, ...
Jun 30, 2025
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IncRNA's role in triple-negative breast cancer provides potential inroads to much-needed therapies
Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable. The exception is a particularly aggressive variant known as triple-negative ...
Jun 30, 2025
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Scientists uncover mutation tied to poor outcomes in transplant patients
Organ transplantation has significantly revolutionized the treatment of patients with organ failure. However, the recipient's immune system recognizes transplanted organs as foreign and elicits a defensive response that can ...
Jun 30, 2025
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The UK's plan to genetically test all newborns sounds smart—until it creates patients who aren't sick
By 2030, every baby born in the UK could have their entire genome sequenced under a new NHS initiative to "predict and prevent illness." This would dramatically expand the current heel-prick test, which checks for nine rare ...
Jun 30, 2025
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Precursors to bone marrow cancer can stop themselves by entering dormant state
Why do some patients with precursors to bone marrow cancer never develop the disease? Researchers from the Department of Forensic Medicine at Aarhus University have discovered that some cells enter a dormant state and create ...
Jun 27, 2025
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Touch-sensing PIEZO2 ion channel found to also play essential role in coronary vessel development
The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in Nature Cardiovascular Research. ...
Jun 27, 2025
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Two classes of FOXA1 mutations found to drive prostate cancer and therapy resistance
A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene—commonly altered in prostate cancer—drive tumor initiation ...
Jun 27, 2025
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Genomics software processes datasets 100 times faster than current tools to advance cancer research
A new tool—seen as the Google Earth for genomics—will transform how scientists visualize and analyze genomic data, advancing cancer research techniques.
Jun 27, 2025
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Genetics study leads to large-scale diabetes clinical trial launch in Chinese hospitals
Scientists have refined a new way of using genetics to identify whether someone has type 1 or type 2 diabetes in Chinese populations—and it is now being used in a large clinical trial to improve treatment in the region.
Jun 27, 2025
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Exploring major findings from the past half-decade in psychiatric genomics
A new update, led by researchers at the UNC School of Medicine and the Gillings School of Global Public Health, describes major findings from the past half decade in the realm of psychiatric genomics and next steps for researchers.
Jun 27, 2025
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Saliva analysis could reveal risk of developing cancer, heart disease or Parkinson's using molecular markers
A research team led by the University of the Basque Country has identified hundreds of molecular markers in saliva that could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, ...
Jun 26, 2025
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New study reveals genetic link between brain criticality and human cognition
A new study has revealed compelling evidence that brain criticality—a dynamic balance between neural excitation and inhibition—has a strong genetic foundation and is associated with cognitive performance. The research ...
Jun 25, 2025
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Spatial mapping reveals network of cells and genes involved in Crohn's disease complication
Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the gut becomes scarred and obstructed, causing pain and bloating. Currently, the only treatment option ...
Jun 25, 2025
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Gene therapy may slow loss of motor function in ALS
Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.
Jun 25, 2025
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Aggressive blood cancer: A key protein could pave the way for targeted therapies
Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential. While chemotherapy and targeted drugs have improved outcomes for some ...
Jun 25, 2025
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