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Immunology news

Genetics

Genes linked to death from sepsis identified in mice

Sepsis is a life-threatening condition that occurs when the body's immune response to infection spirals out of control. Bacteria in the bloodstream trigger immune cells to release powerful molecules called cytokines to quickly ...

Medical research

Toxin responsible for Legionella growth identified

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps ...

Medical research

Gut microbes may affect the course of ALS

Researchers at the Weizmann Institute of Science have shown in mice that intestinal microbes, collectively termed the gut microbiome, may affect the course of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's ...

Medical research

Encephalitis identified as rare toxicity of immunotherapy treatment

After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center (VICC) investigated why the complication occurred, performing a molecular ...

Diseases, Conditions, Syndromes

First impressions go a long way in the immune system

First impressions are important—they can set the stage for the entire course of a relationship. The same is true for the impressions the cells of our immune system form when they first meet a new bacterium. Using this insight, ...

Immunology

Home birth may start babies off with health-promoting microbes

For all of human history, babies have been born where their mothers lived—whether in a house, hut or cave. Only in the last century has birth moved out of the home and into the hospital. How has that changed the types of ...

Immunology

Cracks in the skin of eczema patients promote allergic diseases

Infants who develop eczema are more likely to develop food allergies, hay fever and asthma as they grow older, a progression known as the atopic march. Donald Leung, MD, Ph.D., head of Pediatric Allergy & Clinical Immunology ...

HIV & AIDS

HIV-infected cells persist in CSF in individuals on long-term ART

(HealthDay)—About half of HIV-positive individuals on long-term antiretroviral therapy (ART) have HIV-infected cells in their cerebrospinal fluid (CSF), according to a study published online July 15 in the Journal of Clinical ...

Diseases, Conditions, Syndromes

Scientists uncover mechanism behind development of viral infections

A team of researchers from the SingHealth Duke-NUS Academic Medicine Centre's Viral Research and Experimental Medicine Centre (ViREMiCS) found that immune cells undergoing stress and an altered metabolism are the reasons ...

Immunology

A genomic barcode tracker for immune cells

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient's own immune system.

Immunology

Holes in the immune system left unrepaired despite drug therapy

If they don't receive antiretroviral therapy (ART), most HIV patients see a progressive weakening of their immune system. But a very small percentage of patients—0.3%—spontaneously control the virus themselves, without ...