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Immunology news
Immunology
Stem cell engineering progress paves way for next-generation living drugs
For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human immune cell—known as helper T cells—from stem cells in a controlled laboratory ...
2 hours ago
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High glutamine levels suppress immune response in head and neck cancer tumors
A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers from The University ...
20 hours ago
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Uncovering why cancer immunotherapy leads to heart inflammation
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by using the patient's own T-cells to target tumors. However, they can cause rare, but potentially fatal cardiac inflammation known as ICI-myocarditis. ...
23 hours ago
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Natural 'decoy receptor' protects against inflammatory bowel disease, research reveals
In a study published in Nature Immunology on January 6, a research team led by Prof. Qian Youcun from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences identified a new member of the ...
Jan 7, 2026
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Common brain parasite can infect your immune cells—here's why that's probably OK
The parasite that may already live in your brain can infect the very immune cells trying to destroy it, but new UVA Health research reveals how our bodies keep it under control.
Jan 7, 2026
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Pain-sensing neurons kick-start immune responses that drive allergies and asthma
Pain-sensing neurons in the gut kindle inflammatory immune responses that cause allergies and asthma, according to a new study by Weill Cornell Medicine. The findings, published in Nature, suggest that current drugs may not ...
Jan 7, 2026
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Immune system plays a major role in brain damage after repeated concussions, study suggests
From football fields to military training grounds, head injuries are leaving lasting marks on the brain in ways we're only beginning to understand. Repeated concussions can increase the risk of mood issues, memory loss and ...
Jan 7, 2026
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As we age, immune cells protect the spinal cord, study reveals
Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord from age-related damage. The results, which may contribute to new knowledge about how certain neurological ...
Jan 7, 2026
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Treatment developed for advanced prostate cancer that could eliminate severe side effects
Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.
Jan 7, 2026
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Immune sabotage: How a Vitamin A byproduct compromises the body's normal anti-cancer response
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic acid—compromises both the body's ...
Jan 6, 2026
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Proximity matters: Claudin-1 as an unexpected guardian of central tolerance
Scientists from the Institute of Molecular Genetics of the Czech Academy of Sciences, in collaboration with the Faculty of Science at Charles University, have uncovered a completely new role for the protein Claudin-1 in the ...
Jan 5, 2026
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Lifting cancer's invisibility cloak: Dying tumor cells alert the immune system
The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or cancerous cells. But tumor cells develop many features that help them hide from the immune system to ...
Jan 5, 2026
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High-dose risankizumab trial tests staying power against psoriasis
Oregon Medical Research Center in Portland, Oregon, has led a phase 2 trial in moderate-to-severe plaque psoriasis that paired higher-than-approved doses of risankizumab with extended follow-up and found high early skin clearance ...
Potential biomarker linked to multiple sclerosis progression and brain inflammation
A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.
Jan 2, 2026
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Tumor bacteria linked to immunotherapy resistance in head and neck cancer
Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.
Jan 2, 2026
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A mother's circadian rhythm may predict her child's vulnerability to bacterial infection
In laboratory models, researchers at The University of Texas MD Anderson Cancer Center discovered that a mother's circadian rhythms, or internal body clock, can influence the immune system states of her offspring, which can ...
Jan 2, 2026
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Combination therapy for Burkitt's lymphoma dramatically improves cure rates in mice
Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most often in children and young adults. In recent years, CAR-T cell therapy—often referred to as a "living ...
Jan 2, 2026
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Loss of vitamin C synthesis protects animals from deadly schistosome infection
Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a benefit of vitamin C deficiency: protection from a major parasitic disease. Their research suggests an explanation for ...
Dec 30, 2025
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Brain immune cells may drive more damage in females than males with Alzheimer's
More than 7 million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester ...
Dec 30, 2025
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How pregnancy and breastfeeding enhance local immunity that cancer-proof the breast
For centuries, physicians observed that nuns, who are celibate, had much higher rates of breast cancer, leading to the theory that pregnancy, childbirth, and breastfeeding might be associated with lower breast cancer risk. ...
New antivirals are being tested for herpesviruses, and scientists now know how they work
Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.
Dec 29, 2025
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Melanoma cancer cells secrete extracellular vesicles to paralyze immune cells
A new international study led by Prof. Carmit Levy of the Department of Human Genetics and Biochemistry at the Gray Faculty of Medical & Health Sciences at Tel Aviv University finds that melanoma cancer cells paralyze immune ...
Dec 29, 2025
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Blocking a key gene regulator may restore immune response in cancer therapy
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target tumors. Despite their initial clinical success, many patients eventually experience diminished therapeutic ...
Dec 29, 2025
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Low-dose peanut therapy shown to protect children with peanut allergies
Children with peanut allergies may not need large doses of peanut oral immunotherapy (OIT) to build protection against peanuts, finds a new study led by The Hospital for Sick Children (SickKids) and Montreal Children's Hospital.
Dec 29, 2025
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