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Allergy and immunology news
Macrophages need constant reminders to retain memories of prior infections, researchers discover
Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling molecules left behind ...
14 hours ago
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Missing ANGPTL4 gene in mice reprograms immunity, shielding against gut inflammation
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. ...
8 hours ago
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Vascularized liver tissueoid-on-a-chip models regeneration and transplant rejection
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling ...
8 hours ago
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How age, sex and genetics shape our antibodies
Age, biological sex, and human genetic factors influence the production of antibodies during the immune response. A team of scientists from the Institut Pasteur, the CNRS and the Collège de France have shown that these factors ...
7 hours ago
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NIH institute told to drop 'biodefense' and 'pandemic preparedness' language from website
As new infectious threats emerge worldwide, a key U.S. health agency is quietly stepping away from language tied to pandemic planning, a change some experts warn could leave Americans less protected when the next crisis hits.
7 hours ago
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Mint, eucalyptus and chili compounds reveal powerful synergy against inflammation in immune cells
Many everyday foods and seasonings—such as herbs, spices, and aromatic plants—contain natural compounds called phytochemicals that can regulate inflammatory pathways. For centuries, these ingredients have been used together ...
Feb 17, 2026
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Allergic conjunctivitis linked to increased risk for keratoconus
For patients aged 5 to 25 years, allergic conjunctivitis is associated with an increased risk for keratoconus and increased corneal diagnostic procedures, according to a study published in the February issue of Contact Lens ...
Feb 17, 2026
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How vaccines give our immune systems a home advantage
We are now approaching six years since COVID-19 was declared a pandemic by the World Health Organization, yet talk of vaccines and our immune systems persists in our cultural conversations—from political arenas to the dinner ...
Feb 17, 2026
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Blocking both drug-resistant bacteria and influenza with a broad-spectrum infection prevention approach
Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine. In particular, mixed bacterial-viral infections in critically ill or immunocompromised ...
Feb 16, 2026
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Dual brakes on T-cells: New targets found to boost immunity in chronic infections
Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve treatments to control chronic ...
Feb 16, 2026
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Optimizing CAR T-cell therapy to tackle solid tumors
In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite prostaglandin E2 can block T cells—the killer cells of the immune system—in the vicinity of a tumor, ...
Feb 16, 2026
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Mouse study reveals local antibody 'brakes' shape B cell selection
A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized mechanism that shapes ...
Feb 16, 2026
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Machine learning model predicts serious transplant complications months before symptoms appear
A powerful artificial intelligence (AI) tool could give clinicians a head start in identifying life-threatening complications after stem cell and bone marrow transplants, according to new research from MUSC Hollings Cancer ...
Feb 16, 2026
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In Cordoba, the grass pollen season has grown longer over the last 23 years
A study analyzes the relationship between pollen and meteorological data spanning 23 years, verifying how the wind impacts each phase of the pollen season differently, thereby helping to manage and prevent allergy seasons. ...
Feb 13, 2026
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Why visceral fat triggers diabetes: Study points to loss of protective macrophages
Scientists at the University of Pittsburgh School of Medicine discovered a surprising new way the body can fight insulin resistance and diabetes—by boosting a special type of "good" immune cell in fat tissue.
Feb 12, 2026
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Unraveling the mystery of why some cancer treatments stop working
Cancer researchers working on immunotherapies have made a big discovery: SLAMF6, a molecule on the surface of immune cells that prevents T cells from effectively attacking tumors—and, in mice, they've found a way to neutralize ...
Feb 12, 2026
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Rallying more T-cells to immunotherapy's fight against cancer
Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...
Feb 12, 2026
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Gut microbiome may be the link to gluten sensitivity without celiac disease
The gut microbiome may play an important role in how the immune system responds to gluten, even in people who do not have celiac disease. The findings, which could help explain why some people feel sick after eating gluten, ...
Feb 12, 2026
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Major depressive disorder shares immune abnormalities and potential therapies with inflammatory skin diseases
A team of leading clinical research scientists from the Departments of Psychiatry and Dermatology at the Icahn School of Medicine at Mount Sinai has found that the serum of patients with major depressive disorder shares immune ...
Feb 11, 2026
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Shining new light on how cytokines manage immune response
Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses molecules called cytokines to ...
Feb 11, 2026
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Why asthma can hit women harder: Estrogen-linked IL-33 ramps up lung inflammation
Asthma affects millions of people worldwide, and adult women experience the condition more frequently—and often more severely—than men. Symptoms can also fluctuate during puberty, pregnancy and menopause, yet the biological ...
Feb 11, 2026
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Researchers solve mystery behind rare clotting after adenoviral vaccines or natural adenovirus infection
A global research collaboration of scientists from McMaster University (Canada), Flinders University (Australia) and Universitätsmedizin Greifswald (Germany) uncovered why a small number of people developed dangerous blood ...
Feb 11, 2026
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Harnessing antiviral memory to fight tumors: Redirected antibodies show promise
Because many different types of cancer cells overexpress programmed death-ligand 1 (PD-L1), this cell surface protein is a major target of cancer immunotherapy. Unfortunately, drugs that target it do not trigger especially ...
Feb 11, 2026
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Airborne toxins trigger a unique form of chronic sinus disease in veterans
Researchers at the University of California San Diego and the Veterans Affairs San Diego Healthcare System have identified a distinct biological pattern of chronic rhinosinusitis (CRS), a chronic respiratory illness frequently ...
Feb 11, 2026
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Study finds immune markers at two months tied to longer survival in glioblastoma trial
Researchers at The University of Texas MD Anderson Cancer Center have identified blood-based biomarkers that can help distinguish patients with glioblastoma who are most likely to live longer from novel treatment with an ...
Feb 11, 2026
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