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Allergy and immunology news
Therapeutic, nasally delivered DNA vaccine fuses two genes to help fight tuberculosis
In a paper published in the Journal of Clinical Investigation, a research team at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health reports developing a therapeutic intranasal (nose-delivered) ...
6 hours ago
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How T cells amplify signals: New study reveals key molecular switch
Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be precisely amplified to mount an effective defense against invasive threats. New research by immunologists ...
14 hours ago
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Small intestinal bacterial overgrowth linked to worsening symptoms in allergic diseases
Allergies are usually associated with the immune system, genetics, and environmental factors. Increasingly, however, another element is appearing in this puzzle: the gut microbiota. A review of studies published in the International ...
5 hours ago
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Outcomes superior for endoscopic sinus surgery + Vidian neurectomy in allergic rhinitis with chronic rhinosinusitis
For patients with allergic rhinitis and chronic rhinosinusitis, the addition of vidian neurectomy to endoscopic sinus surgery (ESS) is associated with superior improvements in symptoms and nasal function, according to a study ...
21 hours ago
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Cysteine pathways help T cells choose between multiplying and attacking tumors
A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health has discovered how the immune system's CD8+ T cells ...
Mar 31, 2026
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Scientists capture early stages of immune response inside cells
In new research, scientists at the Department of Energy's SLAC National Accelerator Laboratory, in collaboration with researchers at Harvard University and Brigham Young University, used the Stanford-SLAC Cryo-EM Center to ...
Mar 31, 2026
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Study maps hidden immune signals in type 1 diabetes
Type 1 diabetes researchers have made great progress in understanding the disease in the last two decades, even as a cure remains elusive. Now they have something that benefits any scientific effort. It's a map.
Mar 31, 2026
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Bacterial-like vaccine cues could help extend immunity against evolving viruses
Researchers at the University of Wisconsin School of Veterinary Medicine have identified a possible way to make longer-lasting vaccines for respiratory viruses like influenza and the coronavirus that causes COVID-19. The ...
Mar 31, 2026
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Spleen identified as new target in stroke recovery
Scientists have uncovered an important new link between the brain and immune system after stroke, which could lead to potential new treatments to improve recovery and reduce long-term disability. In new research published ...
Mar 31, 2026
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Reactivation of dormant regulatory T cells alleviates asthma symptoms in mice
A collaborative effort among researchers at the Henan Academy of Innovations in Medical Science, Zhengzhou University, and Shenzhen University School of Medicine has provided the first proof-of-principle study demonstrating ...
Mar 31, 2026
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Orthodontics researchers evaluate microplastics' effect on immune system
In a new study, orthodontics researchers at the University at Buffalo School of Dental Medicine recently discovered how synthetic polymers, including clear aligners, retainers and sleep devices, may affect the immune system. ...
Mar 31, 2026
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How bacteria outsmart the immune system: Two-pronged strategy revealed
Researchers have uncovered how a disease-causing bacterium uses a single protein to interfere with the body's defenses in more than one way, offering a clearer picture of how infections take hold at the cellular level. The ...
Mar 30, 2026
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No link found between childhood atopic dermatitis and markers of cardiovascular risk
Atopic dermatitis (AD) during childhood is not associated with increases in markers of cardiovascular risk, according to a study published online March 24 in JAMA Network Open.
Mar 29, 2026
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FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder
Dr. Donald Kohn has been developing gene therapies for rare pediatric immune disorders for over 30 years. This week, his role in a clinical trial has culminated in the first-ever U.S. Food and Drug Administration–approved ...
Mar 28, 2026
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Gut 'primes' pathogenic T cells responsible for neuroinflammation in multiple sclerosis, study finds
Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS). What makes the body turn against itself? ...
Mar 27, 2026
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Vitamin D supplements may shift immune responses to gut bacteria in IBD
Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a Mayo Clinic-led study published in Cell Reports Medicine.
Mar 26, 2026
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Designing global flu vaccines? Studies suggest common IGHD deletions may block key antibodies
Inherited variations in antibody genes can affect how we respond to infections and vaccines, show two new studies from Karolinska Institutet published in the journal Immunity. The researchers have mapped immune gene variation ...
Mar 26, 2026
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Single-cell study reveals how immune memory cells remember threats
Scientists at Cincinnati Children's have identified how certain immune cells are molecularly programmed to respond faster when the body encounters a familiar threat, shedding light on immune memory and its links to diseases ...
Mar 26, 2026
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A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment
In 2023, researchers at Baylor College of Medicine led by the late Dr. Bert O'Malley discovered that the steroid receptor coactivator 3 (SRC-3) in immune cells called regulatory T cells (Tregs) plays a decisive role in shaping ...
Mar 26, 2026
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How some autoantibodies contribute to clots: The C4BP link and a path to treatment
Northwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to blood clots, pregnancy complications and other inflammatory conditions, according to a new study published ...
Mar 26, 2026
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Why do some viruses linger for life? A 900,000-person study maps viral loads
Some viruses that make us sick are cleared by the immune system within days, while others lurk in our bodies for a lifetime and reemerge later to cause new problems. How and why viral levels in the body change over time—and ...
Mar 25, 2026
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Immune response to cancer may cause autoimmune disorders, including anti-NMDA receptor encephalitis
Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated. If cancer arises from cellular mutation, why don't we all have the disease ...
Mar 25, 2026
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Single-cell maps show chemokine signals collapse as aggressive lymphoma spreads
Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections and tumors. For these processes to function properly, immune cells (B cells and T cells) must be ...
Mar 25, 2026
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How STING gets moving: Study identifies transport protein key to immune response
UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of interferon genes (STING) migrates from one cellular organelle to another, a necessary step in its activation. ...
Mar 25, 2026
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Living with dogs: Examining asthma outcomes in children
Living with a dog does not seem to worsen long-term asthma severity in children with allergic asthma, but may increase the risk of asthma exacerbations slightly, according to a study from Karolinska Institutet in Sweden that ...
Mar 25, 2026
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