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Allergy and immunology news
Engineered immune cells help reduce toxic proteins in the brain
Chimeric antigen receptor (CAR) T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option for certain cancers. The treatment relies on genetically modified ...
13 hours ago
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Researchers uncover lymph-to-vein shortcuts inside lymph nodes, challenging dogma
Our lymphatic system is like a big network of roots spread throughout the body. It serves as part of our immune system, transporting immune cells and filtering excess fluid (lymph) before returning it to the bloodstream. ...
11 hours ago
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Study explores link between hormonal contraceptives and chronic rhinosinusitis in women
A comprehensive study analyzing data from nearly 240,000 women has found that estrogen-containing hormonal contraceptives are associated with a significantly lower risk of chronic rhinosinusitis without nasal polyps (CRSsNP), ...
15 hours ago
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ABCA1 protein releases molecular brakes on solid tumor immunotherapy, study finds
In recent years, cancer researchers have made major breakthroughs by using the body's immune system to fight cancer. One of the most promising approaches, known as immune checkpoint blockade, works by releasing molecular ...
Feb 6, 2026
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Immune cells linked to Epstein-Barr virus may play a role in multiple sclerosis
Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million Americans. The work found ...
Feb 5, 2026
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How 'invisible' vaccine scaffolding boosts HIV immune response
One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics ...
Feb 5, 2026
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Fatty acids found to influence immune defense during chronic infections
Our immune system implements an array of strategies to combat threatening infections. White blood cells called cytotoxic T lymphocytes or "CD8 T cells" are soldiers of the immune system, serving as defensive agents that fight ...
Feb 5, 2026
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Immune 'hijacking' by tumors can predict cancer evolution
Predicting tumor progression is one of the major challenges in oncology. Scientists at the University of Geneva (UNIGE) and the Ludwig Institute for Cancer Research have discovered that neutrophils, a type of immune cell, ...
Feb 5, 2026
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Targeting HIV's hidden reservoirs: Lab-enhanced natural killer cells show promise
More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme on HIV/AIDS (UNAIDS). The drugs are effective ...
Feb 5, 2026
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Gut microbe-derived butyrate activates immune cells to enhance vaccine efficacy
A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing how butyrate—a short-chain fatty acid produced by gut commensal bacteria—enhances T follicular ...
Feb 5, 2026
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Five mutational 'fingerprints' could help predict how visible tumors are to the immune system
Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's not simply the number of tumor mutations that matters for immunotherapy, but the kind of mutation ...
Feb 5, 2026
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Why antibiotic allergy labels deserve a second look
In modern medicine, antibiotics are among the most powerful tools for preventing and treating life-threatening bacterial infections. Their effectiveness, however, often depends on using the right drug at the right time. Recognizing ...
Feb 5, 2026
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Overactive immune cells can worsen heart failure. Targeting them could offer new treatments
Around 64 million people worldwide suffer from heart failure, and nearly half die within the first five years of diagnosis due to a lack of effective treatments to stop the disease from getting worse.
Feb 5, 2026
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An off-the-shelf immunotherapy for targeting solid tumors: Ready-to-use CAR-NKT cells show promise
A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to treat multiple solid tumors. The study focused on engineered invariant natural killer T cells, or ...
Feb 4, 2026
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A genetic blueprint for avoiding killer T cell exhaustion
A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune ...
Feb 4, 2026
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B cells join T cells to drive sight-threatening arthritis in children
A team led by UCL researchers with Great Ormond Street Hospital (GOSH) and Moorfields Eye Hospital, found B cells—alongside T cells—play a key role in arthritis-related eye disease (JIA uveitis), a condition that can ...
Feb 4, 2026
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A single skin gene helps build the body's first line of immune defense
Researchers at Ben-Gurion University of the Negev (BGU) have discovered that a gene long known for shaping the skin's physical barrier also plays a crucial role in building and maintaining the skin's immune defense. The findings, ...
Feb 3, 2026
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Yeast cells can be used for rapid testing of cancer immunotherapy
An international research team with strong participation from DTU has developed a new biotechnological platform that makes it possible to test and understand advanced cancer treatments much faster and cheaper than before. ...
Feb 3, 2026
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A more reliable platform to test antibody medicines
An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how antibody medicines are tested and brought to patients. The work, published in Science Immunology, ...
Feb 2, 2026
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In developing immunity to allergens, a little 'dirty' goes a long way
Conventional wisdom has held for some time that children who grow up in environments rich with biodiversity—farms, homes with pets, rural settings in general—are less likely to have allergies. The thing nobody has ever ...
Jan 31, 2026
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Alternate path for inflammation could improve rheumatoid arthritis treatment
The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients.
Jan 30, 2026
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A benchmark for antibodies: Open dataset aims to standardize sequencing and measurement
Antibodies are the immune system's precision tools for recognizing and neutralizing viruses, bacteria and other foreign substances that can make us ill. These proteins circulate in the bloodstream and are built from chains ...
Jan 30, 2026
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How does long COVID develop? New piece of the puzzle found
How long COVID develops is still largely unknown. New molecular connections are revealed in a recent study led by the Center for Individualized Infection Medicine (CiiM), which is a joint institution of the Helmholtz Center ...
Jan 29, 2026
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