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Allergy and immunology news

Study identifies new strategy to overcome immunotherapy resistance in colorectal cancer

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have identified a promising new strategy to overcome resistance to immunotherapy in colorectal cancer, one of the leading ...

Hidden sex differences may explain why lupus strikes women far more often

Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and UNSW Sydney helps explain why women are significantly more likely to be diagnosed with an autoimmune disease—a condition where ...

Turning up the volume on macrophage-driven immune responses

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system. However, the ability of macrophages to interpret and respond to diverse danger signals remains ...

Controlled peanut intake may reduce allergies in toddlers

Researchers at Karolinska Institutet have successfully treated children aged 1–3 years with peanut allergies. The children slowly became accustomed to eating peanuts by consuming small amounts of them daily, which were gradually ...

Ticked off: How a bite can turn meat against you

Mammalian meat allergy (MMA) is one of the few known food allergies caused by an environmental trigger—a tick bite. In simple terms, MMA results in an allergic reaction to red meat, making it difficult or sometimes even impossible ...

Your nose may be the gateway to a stronger immune system

At the moment, an influenza vaccine called FluMist is the only licensed intranasal vaccine approved for use in humans. The vaccine is administered through a spray of fluid in the nose, rather than with an injection.

How immune cell networks drive liver disease

A type of rare T cell triggers a cascade of signals amplifying inflammation and ultimately leading to liver fibrosis, according to a new study from Julius Maximilian University of Würzburg published in Nature Communications. ...

Cutting calories to slow aging—without compromising health

Restricting calorie intake in species such as mice, rhesus monkeys, and fruit flies has been shown to extend their lifespans. In some cases, these animals not only live longer, but are also free of disease. But when pushed ...

Older mice may offer new insight into cancer and aging

Cancer risk increases with age and is often more aggressive and difficult to treat in older adults. However, fewer than 10% of mouse studies use aged animals, with most relying on mice roughly equivalent to humans in their ...