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Immunology news
Oncology & Cancer
Scientists develop targeted therapy for T-cell lymphomas and leukemias
Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive ...
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Does being infected or vaccinated first influence COVID-19 immunity?
A new study analyzing the immune response to COVID-19 in a Catalan cohort of health workers sheds light on an important question: does it matter whether a person was first infected or first vaccinated?
Dec 23, 2025
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Study reveals low immunity against H3N2 strain in Hong Kong: Early vaccination urged
Flu activity has surged in many parts of the Northern Hemisphere, driven primarily by a newly emerged H3N2 strain known as subclade K.
Dec 23, 2025
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A new strategy for immune tolerance: Engineered extracellular vesicles show promise
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific ...
Dec 22, 2025
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Eczema injectable drug provides quick itch relief, clinical trial results show
A recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.
Dec 20, 2025
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RNA steps outside the cell to help guide immune responses, study suggests
RNA is usually portrayed as a molecule that works deep inside the cell, helping to turn genetic information into proteins. But new research led by Utrecht University scientist Jack Li shows that RNA also plays an active role ...
Dec 19, 2025
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What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism
When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent fates—one cell becomes ...
Dec 19, 2025
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Study examines oligodendrocyte dynamics throughout the progression of multiple sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by the disruption of nerve signals and various associated neurological symptoms, ranging from vision problems to numbness, weakness, fatigue and cognitive ...
Most parents are aware of early peanut introduction guidelines—but confused about the details
Feeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new study published in JAMA Network Open found that parents need more support to get it right. Interviews with parents revealed ...
Dec 18, 2025
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Key lung immune cells can intensify allergic reactions
Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...
Dec 18, 2025
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Scientists map structure of antibodies driving rare autoimmune brain disease
MOG antibody-associated disease (MOGAD) is a rare autoimmune disease of the central nervous system. The blood of patients contains antibodies against myelin oligodendrocyte glycoprotein (MOG), a protein in the myelin layer ...
Dec 18, 2025
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Promising target improves antitumor response in preclinical models of pancreatic cancer
Researchers at The University of Texas MD Anderson Cancer Center have found that a mitochondrial enzyme, GFER, creates an immunosuppressive environment within pancreatic tumors, leading to treatment resistance.
Dec 18, 2025
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Engineered dendritic cells boost cancer immunotherapy
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.
Dec 17, 2025
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Microbiome may aid in healthy pregnancies by training maternal immune system
Gut microbes may play a key role in training a mother's immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.
Dec 17, 2025
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Astrocytes found to aid spinal cord repair by signaling immune response
Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple sclerosis. Their study, ...
Dec 17, 2025
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Liver cell reprogramming boosts T cell function in aging immune systems
As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, making people more susceptible to a variety of infections.
Dec 17, 2025
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Individual genetic differences can render some antibody-based therapies ineffective
Antibody-based therapies are used to treat numerous diseases, from cancer to rheumatic disorders and multiple sclerosis. Antibodies recognize and bind to very specific structures. This allows them to direct active substances ...
Dec 17, 2025
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Chronic fatigue syndrome linked to widespread energy, immune and vascular changes
New Australian research has identified simultaneous abnormalities across multiple biological systems in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Dec 17, 2025
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COVID-19 virus manipulates host cell RNA to shut down the immune system, study reveals
Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered that SARS-CoV-2, the virus that causes COVID-19, uses a sophisticated tactic to evade the human body's defense system. In addition to ...
Dec 17, 2025
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses
mRNA vaccines, such as those used against COVID-19, are effective at generating antibody responses. These antibodies are produced through specialized immune structures called germinal centers, but until now it was not fully ...
Dec 17, 2025
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Ultrasensitive liquid biopsy affective in predicting and monitoring immunotherapy response, study shows
Published today in Clinical Cancer Research, findings from a study led by investigators at the Vall d'Hebron Institute of Oncology (VHIO), which forms part of the Vall d'Hebron Campus, underscore the efficacy of analyzing ...
Dec 17, 2025
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Black patients diagnosed with aggressive leukemia experience worse outcomes
Compared with white patients, Black patients with an aggressive form of leukemia—called acute myeloid leukemia (AML)—were on average more than five years younger at diagnosis and more than 30% more likely to die of their ...
Dec 17, 2025
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New understanding of T cell receptors may improve cancer immunotherapies
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full ...
Dec 16, 2025
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Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'
Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.
Dec 16, 2025
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