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Allergy and immunology news
New approach opens rare immune cells to genetic risk research
Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA ...
16 hours ago
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Placental transport mechanism could guide safer biologic medicines during pregnancy
Biologic medicines have transformed the treatment of cancer, autoimmune diseases, migraine, inflammatory disorders and many other conditions. Yet their growing use among women of reproductive age constitutes a major clinical ...
Aug 14, 2026
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New mechanism may help predict and improve macrophage-targeted cancer immunotherapy
Immunotherapy that targets tumor-associated macrophages, a type of immune cell in the tumor microenvironment, works only if the cells have a functional system of molecules that enables them to respond to the treatment. This ...
Aug 14, 2026
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Winter is coming: How vaccines help protect against respiratory illness
August is National Immunization Awareness Month—the perfect time to prepare for the viruses and bacteria that spread each fall and winter.
Aug 14, 2026
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Scientists uncover 'hidden switch' that helps cancer cells hide from the immune system
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body's ...
Aug 13, 2026
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New spike map shows how SARS-CoV-2 variants dodge key antibodies
Antibodies are an important defense against SARS-CoV-2, but the virus continues to evolve ways to evade them. Now, researchers have mapped how antibodies target a key region of the virus's spike protein, how they neutralize ...
Aug 13, 2026
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In vivo CRISPR screen identifies gene edits that strengthen CAR-T therapy against solid tumors
For patients with blood cancers like leukemia and lymphoma, the immunotherapy known as CAR-T cell therapy can be lifesaving. Doctors remove a patient's immune cells, called T cells, engineer them in the lab to better recognize ...
Aug 12, 2026
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Finding a tumor's soft spot to power-up immunotherapy
Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of ...
Aug 12, 2026
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Dysregulated immune cells may cause silent inflammation after heart attack
Coronary artery disease, which is caused by plaque buildup in the arteries that supply blood to the heart, can appear stable for long periods without causing any symptoms. But the disease can become unstable at any time and ...
Aug 12, 2026
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Scientists uncover drivers of recurrent arthritis after immunotherapy, suggesting potential biomarkers
A new study led by researchers at The University of Texas MD Anderson Cancer Center has shown that inflammatory arthritis occurring as a side effect of immune checkpoint inhibitors behaves like an immune-memory disease, suggesting ...
Aug 12, 2026
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Humanized mouse model could significantly improve preclinical research on drugs for celiac disease
Celiac disease is an autoimmune disorder in which the immune system reacts to gluten. More than 1% of the population in Germany is affected. In these individuals, gluten proteins found in wheat, rye and barley trigger inflammation ...
Aug 12, 2026
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Computational framework identifies novel pathway for asthma inflammation
Researchers at Columbia University Mailman School of Public Health, in collaboration with investigators at the University of Chicago, have developed a new computational framework that helps scientists identify genes that ...
Aug 11, 2026
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Cells' own abnormal RNA may trigger inflammation during viral infection, challenging 20 years of assumptions
New research led by the Hudson Institute of Medical Research has shown how a cell recognizes that it is infected with a virus to protect itself and surrounding cells or induce inflammation. The discovery, published in Nature ...
Aug 11, 2026
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Brain immune cell map explains how defenses shift during Alzheimer's progression
The brain's immune cells are increasingly recognized as key players in Alzheimer's disease, but exactly how they change as the disease develops has remained unclear. A new study published in Nature Genetics provides the most ...
Aug 11, 2026
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Immune cells rely on a cholesterol sensor to maintain balance, researchers discover
Every day, billions of cells in our body die and are removed as part of normal tissue maintenance. This continuous cleanup process is essential for keeping the immune system in balance and preventing harmful immune reactions ...
Aug 11, 2026
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Genetic variants shed light on kidney transplant rejection
Immunosuppressive medications help prevent organ rejection following transplantation, yet some patients still experience rejection despite receiving adequate treatment. New research from Yale, published in the Journal of ...
Aug 11, 2026
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Differences in immune cells predict skin cancer treatment outcomes
In a first-of-its-kind study by King's College London, researchers have linked changes in two major types of immune cells in blood to different survival outcomes for patients with melanoma. Melanoma, the fifth most common ...
Aug 11, 2026
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Sarcoidosis shifts lung immune-cell communication, single-cell data suggest
Researchers at National Jewish Health and partner institutions have discovered specific changes in immune cells in the lungs of people with sarcoidosis. Their findings help explain how this inflammatory disease develops and ...
Aug 11, 2026
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Solving a mysterious inflammatory fever opens the book on a much bigger story
Three research teams working independently around the world have landed on the same discovery: A single molecular "handshake" inside our cells controls a family of inflammatory diseases, including one of the most common inherited ...
Aug 10, 2026
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Molecular mapping reveals hidden cellular programs in heart transplant rejection
A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.
Aug 10, 2026
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HIV-1 proviruses may drive chronic systemic inflammation
HIV (human immunodeficiency virus) is a virus that attacks the body's immune system and remains a major global health challenge because of persistent viral reservoirs, despite effective treatments. Key factors include around ...
Aug 10, 2026
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New analysis explains why bone marrow cancer T cells may need therapeutic activation
A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow of patients ...
Aug 10, 2026
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How heatstroke kills—it can still be deadly after your body cools down
Europe is in the grip of yet another deadly heat wave. Over 10,000 excess deaths were recorded during late June 2026 alone—and the toll keeps climbing.
Aug 10, 2026
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Why the body's inflammatory alarm misfires in familial Mediterranean fever
Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation. ...
Aug 7, 2026
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