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Allergy and immunology news
Your nose may be the gateway to a stronger immune system
At the moment, an influenza vaccine called FluMist is the only licensed intranasal vaccine approved for use in humans. The vaccine is administered through a spray of fluid in the nose, rather than with an injection.
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B-cell clusters inside kidneys mark faster diabetic disease progression, new maps reveal
A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells—specifically B cells—that are linked to faster disease progression. The findings ...
1 hour ago
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How eating primes immune cells for future responses
Diets and healthy eating habits hold promise for preventing and treating diseases, but far less is known about acute effects on the immune system shortly after a meal.
3 hours ago
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Researchers deepen understanding of molecular pathways responsible for airway inflammation in asthma
Johns Hopkins Medicine researchers say they have identified molecular pathways controlled by the protein RhoA in club cells—a specialized population of epithelial cells that exclusively lines the inner and outer surfaces ...
2 hours ago
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How killer T cells attack tumors in 3D could sharpen future cancer immunotherapy
Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," where they release active ...
6 hours ago
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How the immune system battles lifelong viral infections acquired at birth
Millions of people worldwide carry viral infections they acquired at birth, often for life. For a long time it was assumed that the immune system hardly fights these pathogens. Researchers from the University of Basel show ...
18 hours ago
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Key molecular dynamic could boost cancer treatments while limiting stem cell transplant rejection
A key molecular dynamic could be the key to fighting tumors while allowing patients to still receive life-saving cell transplantation, according to the latest finding published by a team of scientists from the Hackensack ...
19 hours ago
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Why bone metastases resist treatment: New method identifies immune cells shielding tumors
Researchers at Baylor College of Medicine and collaborating institutions have developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary cause of death for most ...
Apr 28, 2026
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T cells, not B cells, are the culprit in kidney damage in lupus, study shows
Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells malfunction and produce antibodies that attack the body's own cells, tissues, and organs.
Apr 28, 2026
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Experimental drug offers new hope for celiac disease treatment
An experimental drug may in future provide a new form of protection for people with celiac disease. According to an international study led by the Universities of Oulu and Tampere, the drug dampens the harmful effects of ...
Apr 28, 2026
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Research uncovers fatal delays in EpiPen treatment for food anaphylaxis in children
Fatal delays in administering life-saving adrenaline autoinjector (EpiPen) for food anaphylaxis, a severe and rapid allergic reaction, are highlighted in research presented at the Royal College of Emergency Medicine Conference. ...
Apr 28, 2026
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Turning immune cells into tumor allies: A cancer cell protein can reprogram frontline defenders
Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, discovered by scientists ...
An unexpected limit to SARS-CoV-2's immune defenses reveal a hidden virus trade-off
A new study has revealed that while SARS-CoV-2 can weaken part of the body's early immune response, it may also unintentionally trigger another defense that helps cells fight back. A new collaborative study has revealed a ...
Apr 27, 2026
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Obesity leaves a lasting memory in immune cells, 10-year study shows
People who live with obesity are "tagging" a memory of being overweight on a key part of the immune system—leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10-year-long ...
Apr 27, 2026
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Key protein in the inflammatory response to infections identified
Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages—cells of the innate immune system—play a key role: first, they help eliminate pathogens ...
Apr 27, 2026
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Inside lungs, tumor position reveals immune shifts missed by other models
Researchers at VIB and VUB have developed a powerful new way to study how the immune system behaves inside lung tumors. By combining a patient-relevant mouse model with single-cell technologies, the team provides one of the ...
Apr 27, 2026
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Unleashing natural killer cells against cancer
Scientists have developed a strategy to boost the cancer-fighting power of natural killer (NK) cells, part of the immune system's first line of defense. NK cells can detect and destroy cancer cells, but tumors often create ...
Apr 27, 2026
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Blocking immune 'signal two' expands gut tolerance cells, may open new IBD treatments
Weill Cornell Medicine investigators made an unexpected finding about how the immune system normally suppresses inappropriate chronic inflammation in the intestine, potentially opening new avenues for therapies against inflammatory ...
Apr 26, 2026
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Antibodies can selectively shut down harmful T cells without weakening whole immune system
The immune system is the frontline protection against infection, continually searching for and destroying unknown pathogens. While typical operation of the immune system scans for threats, some systems attack the body's own ...
Apr 26, 2026
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How a chemical reaction triggers brain inflammation in Alzheimer's disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that ...
Apr 25, 2026
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Hidden in hair follicles, immune 'sentinel' cells may help skin detect microbes
Researchers at the School of Medicine at the University of California, Riverside have discovered previously unrecognized immune surveillance structures in the skin. Found within hair follicles, the cells resemble M (microfold) ...
Apr 25, 2026
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Machine learning predicts asthma risk in children with early-life atopic dermatitis
Machine learning models can predict the risk for developing moderate-to-severe persistent asthma and allergic rhinitis in children diagnosed with early-life atopic dermatitis, according to a study published online April 17 ...
Apr 25, 2026
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Protein's second role in inflammation could reshape treatment for Crohn's, arthritis and heart disease
A protein long understood to drive inflammation by producing nitric oxide has a second, previously unknown role—it physically binds to another key protein inside cells to directly modulate the immune response. The discovery, ...
Apr 24, 2026
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Inside lymph nodes, an overlooked cell type quietly directs immune battles in ways that could reshape medicine
The research group of prof. Sanjiv Luther at the department of immunobiology of the University of Lausanne has discovered that a fibroblast subtype is essential for coordinating certain immune cells within lymph nodes. This ...
Apr 23, 2026
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Autoantibody map uncovers body-wide immune attacks across Alzheimer's, Parkinson's and MS
Researchers at the University of São Paulo (USP) in Brazil discovered that neurodegenerative diseases, such as Alzheimer's, Parkinson's, and multiple sclerosis, are more complex than previously thought. Their analysis of ...
Apr 22, 2026
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