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Immunology news

Oncology & Cancer

Tumor bacteria linked to immunotherapy resistance in head and neck cancer

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

Immunology

Loss of vitamin C synthesis protects animals from deadly schistosome infection

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a benefit of vitamin C deficiency: protection from a major parasitic disease. Their research suggests an explanation for ...

Immunology

Key lung immune cells can intensify allergic reactions

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...

Oncology & Cancer

Engineered dendritic cells boost cancer immunotherapy

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.

Oncology & Cancer

First patient in Arizona treated with new immune cell therapy

A patient with synovial sarcoma, a soft-tissue cancer that usually occurs in the large joints of the arms and legs, is the first in Arizona treated with a new immune cell therapy known as TECELRA at the HonorHealth Research ...

Immunology

CAR T-cell therapy accelerates intestinal healing in aging mice

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ's lining. The intestine plays a crucial ...

Immunology

New vulnerability of asthma immune cells discovered

Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered ...

Psychology & Psychiatry

Short-term stress primes immune cells for action in animal models

Stress affects many systems in our body and biologists Marcel Schaaf and Erin Faught at Radboud University are figuring out how that works. Their recent study showed how stress changes behavior by using two different receptors. ...

Oncology & Cancer

How CAR T-cell therapies target myeloma at the molecular level

In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR T-cell therapy may be considered. ...

Oncology & Cancer

CAR-T therapy yields long-term survival for patients with lymphoma

A study published in the Journal of Clinical Oncology confirms that one of the first Food and Drug Administration-approved CAR-T cell therapies offers long-term survival and potential cures for adult patients with relapsed ...

Immunology

Gut cells aid intestinal healing, hope for IBD patients

A team led by scientists at King's College London, in collaboration with national and international partners, has discovered how a specific group of immune cells in the gut—Group 3 Innate Lymphoid Cells (ILC3s)—promote ...

Immunology

How the immune system stalls weight loss

Researchers at the University of California San Diego School of Medicine have uncovered a surprising new function for immune cells: preventing excess weight loss.

Diseases, Conditions, Syndromes

AI identifies key mpox protein for new vaccine and antibody therapies

With the help of artificial intelligence, an international team of researchers has made the first major inroad to date toward a new and more effective way to fight the monkeypox virus (MPXV), which causes a painful and sometimes ...

Diseases, Conditions, Syndromes

In pneumonia's tug-of-war, lung microbiome could tip the balance

Northwestern University scientists have potentially uncovered a previously unknown, hidden player in pneumonia. In a new study, scientists found the lungs' own microbial community, or microbiome, appears to influence how ...