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Allergy and immunology news
Alternate path for inflammation could improve rheumatoid arthritis treatment
The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients.
18 hours ago
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A benchmark for antibodies: Open dataset aims to standardize sequencing and measurement
Antibodies are the immune system's precision tools for recognizing and neutralizing viruses, bacteria and other foreign substances that can make us ill. These proteins circulate in the bloodstream and are built from chains ...
16 hours ago
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Beyond the active site: A new way to regulate immune enzyme TREX1
The immune system must maintain a delicate balance to defend against harmful threats while avoiding excessive inflammation. When this balance is disrupted, immune responses can contribute to autoimmune diseases and cancer. ...
Jan 29, 2026
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How does long COVID develop? New piece of the puzzle found
How long COVID develops is still largely unknown. New molecular connections are revealed in a recent study led by the Center for Individualized Infection Medicine (CiiM), which is a joint institution of the Helmholtz Center ...
Jan 29, 2026
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Targeting the gut's immune system could tackle early stages of Parkinson's
New research reveals how Parkinson's spreads from the gut to the brain, with the help of immune cells—offering a new potential therapeutic strategy—in a study in mice led by scientists at the UK Dementia Research Institute ...
Jan 28, 2026
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DNA research uncovers 22 genes that could put people at risk of long-term health conditions
Baylor College of Medicine researchers are part of a collaborative research group with AstraZeneca and Memorial Sloan Kettering Cancer Center that have identified 22 genes which increase the risk of developing a range of ...
Jan 28, 2026
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CAR T-cell therapy improves symptoms of myasthenia gravis, clinical trial shows
A new study led by researchers at the UNC School of Medicine and Cartesian Therapeutics, found that immunotherapy can help people with generalized myasthenia gravis, a disease where the body accidentally attacks the cells ...
Jan 28, 2026
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Interferon signal reprograms macrophage mitochondria to promote inflammation resolution, finds study
When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return to homeostasis. Macrophages ...
Jan 28, 2026
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Innovations in asthma care can improve the health of Detroiters living with this chronic disease
Researchers and doctors are beginning to modernize asthma treatment using innovative therapies.
Jan 28, 2026
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Food-induced allergic reactions needing ED visit on the rise in infants
While early allergen introduction may reduce long-term allergy risk, it is tied to an increase in emergency department (ED) visits for food reactions in infancy, according to a study published in the March issue of the Journal ...
Jan 28, 2026
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Team unveils simpler, faster way to make vaccines
UVA Health scientists have developed a promising new way to create vaccines that could be faster, cheaper, and easier to distribute than current options. The University of Virginia School of Medicine's Dr. Steven L. Zeichner ...
Jan 28, 2026
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Leftover COVID spike fragments kill crucial immune cells but are less deadly in omicron
New research shows that after the body's defenses kill the virus behind COVID-19, leftover digested chunks of SARS-CoV-2 spike protein can target specific immune cells based on their shape. The revelations could explain why ...
Jan 27, 2026
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New study finds heart attacks involve brain and immune system, not just heart
Arteries become clogged. Blood flow is restricted and oxygen is cut off. The result is a heart attack, the world's leading cause of death.
Jan 27, 2026
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Antibody-producing immune cells can help shape cancer immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.
Jan 27, 2026
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How your life story leaves epigenetic fingerprints on your immune cells
The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen have such different responses? ...
Jan 27, 2026
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Inflammation and autoimmune-like dysfunction may play a role in heart failure
When the heart's muscle is weakened or injured due to a heart attack, it can make it hard for the heart to pump enough blood to meet the body's needs. Over time, it can lead to heart failure, where the heart's function drops ...
Jan 27, 2026
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Atopic dermatitis under the microscope: Scientists discover the mechanism of itching
Atopic dermatitis (AD) is a chronic disease that affects an increasing number of children and adults. The skin is dry and irritated, and the itching can be so severe that it interferes with sleep and daily life. Although ...
Jan 26, 2026
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Discrimination is linked to diminished immune system function
People who commonly experience everyday discrimination are more likely to have higher levels of "exhausted" white blood cells, suggesting that the chronic stress of discrimination may hamper the immune system, according to ...
Jan 26, 2026
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Fish allergy risk varies by fish size and which part is eaten, research reveals
A new study reveals allergy risks from fish depend not just on species but also on the size of the fish and which part you eat. James Cook University researcher Dr. Thimo Ruethers, who led the study now published in Food ...
Jan 26, 2026
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In rare cases, autoantibodies can cause severe reactions to a discontinued Chikungunya vaccine
A new study published in the Proceedings of the National Academy of Sciences suggests that rare cases of brain inflammation linked to live-attenuated yellow fever and Chikungunya vaccines were due to autoantibodies carried ...
Jan 26, 2026
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Rapamycin helps protect immune cells against DNA damage
As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines are less effective. New research carried out by Dr. Loren Kell at NDORMS shows that immune cells in ...
Jan 26, 2026
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Li-Fraumeni syndrome: How the immune system may shape inherited cancer risk
Li-Fraumeni syndrome is a rare hereditary disease that significantly increases the risk of developing cancer. Almost all affected individuals receive a cancer diagnosis at least once in their lifetime. A new study suggests ...
Jan 26, 2026
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Antibodies targeting IgE Cε2 domain show promise for rapid allergy relief
Allergic diseases represent a major global health burden, placing significant strain on health care systems worldwide. Severe conditions such as anaphylaxis, asthma, food allergy, and allergic rhinitis are driven by immunoglobulin ...
Jan 26, 2026
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Pollen exposure linked to worse quality of life for chronic sinus infection sufferers
The results of a pilot study suggest that long-term exposure to higher pollen levels leads to worse symptoms and quality of life for patients with chronic rhinosinusitis. For the 103 patients studied, levels of ragweed pollen ...
Jan 26, 2026
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Large genetic study uncovers 34 regions linked to allergic conjunctivitis risk
Itchy, red and watery eyes are familiar symptoms for many people, especially during the spring and summer pollen season. Allergic conjunctivitis is a very common condition, but its hereditary background has not previously ...
Jan 26, 2026
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