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Allergy and immunology news

T cell protein could unlock new treatment for the most-feared joint replacement complication

Bone and joint infections cause significant health problems for patients and lead to millions of dollars in added health costs per year, but clinicians lack reliable tools to predict which patients will develop severe or ...

Key path to Alzheimer's-like brain damage starts outside the brain

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains. ...

An immune defect that may set Crohn's disease in motion

Crohn's disease, a condition characterized by widespread inflammation in the gut, may arise from a weakened immune response, according to new research from the University of Toronto's Temerty Faculty of Medicine.

New approach opens rare immune cells to genetic risk research

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA ...

Finding a tumor's soft spot to power-up immunotherapy

Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of ...