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Allergy and immunology news

Bacteria found in mouth and gut may help protect against severe peanut allergic reactions

One of the big mysteries in food allergy is why two people with similar levels of peanut-specific antibodies can react so differently. It turns out the answer may be in the mouth and gut's bacteria. A new study, led by researchers ...

Intranasal vaccine booster shows stronger immune response and protection against sarbecoviruses

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and Monash University in Australia have demonstrated that an intranasal vaccine booster may confer significantly stronger ...

Painless skin patch offers new way to monitor immune health

Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly ...

Smart patch detects allergies before symptoms strike

A wearable device that alerts people with food allergies before a reaction begins has the potential to reduce life-threatening anaphylaxis and transform allergy management from reactive to preventive care. The AllergE patch ...

How a tick could help prevent diseases like MS and cancer

A team from the Monash University Biomedicine Discovery Institute has identified a tick-derived evasin that can bind to two major classes of chemokines, a discovery that is important for the development of therapeutics targeting ...

Paradigm shift in immune checkpoint biology

A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, providing new mechanistic ...

FDA approves Dupixent for allergic fungal rhinosinusitis

The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adult and pediatric patients aged 6 years and older with allergic fungal rhinosinusitis (AFRS) and a history of sino-nasal surgery.

How vaccines give our immune systems a home advantage

We are now approaching six years since COVID-19 was declared a pandemic by the World Health Organization, yet talk of vaccines and our immune systems persists in our cultural conversations—from political arenas to the dinner ...

Optimizing CAR T-cell therapy to tackle solid tumors

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite prostaglandin E2 can block T cells—the killer cells of the immune system—in the vicinity of a tumor, ...

Rallying more T-cells to immunotherapy's fight against cancer

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...

Shining new light on how cytokines manage immune response

Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses molecules called cytokines to ...