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Allergy and immunology news

Key gut protein balances immune protection and tolerance

A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators. The discovery illuminates ...

How immune cells in our gut mesentery fight salmonella

Widely recognized as the face of food poisoning, salmonella bacteria lurk in raw meat and poultry, on pets, and in unpasteurized dairy products. If untreated, extreme cases can lead to full-body infections, like typhoid fever. ...

Study reveals a distinct subtype of eosinophilic esophagitis

Researchers from Ann & Robert H. Lurie Children's Hospital of Chicago identified a distinct subtype of eosinophilic esophagitis (EoE)—a chronic allergic inflammatory disorder in which the esophagus narrows, interfering with ...

Resetting psoriasis memory may help body stop repeat flare-ups

Stress, bad weather, strep throat, alcohol or cuts—there are a number of triggers that can set off psoriasis. At the same time, a great deal is happening in research on this skin disease, and new ways of controlling the immune ...

Rare stem T cells may hold the key to fighting chronic diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition—like a viral infection or cancer—the body needs a steady supply ...

Gut fungi may hold the key to treating asthma worldwide

Two new studies jointly published in Nature Communications reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases—and may be promising ...

Why pollution affects some asthma patients more than others

For many people with asthma, air-quality advisories are harbingers of worsening symptoms. But for reasons science has struggled to explain, the extent to which pollution exacerbates asthma varies widely from person to person.

How RSV manipulates the immune response in respiratory cells

Respiratory syncytial virus (RSV) can cause severe lower respiratory tract infections, particularly in newborns and older adults. How the virus manages to evade the immune system and what changes it triggers in infected cells ...

Can we cure asthma? Yes, and we have a plan

Asthma is conventionally viewed as "treatable but incurable." In other words, we can manage its symptoms but not reverse the underlying condition. But advances in science are challenging this view, and we think a cure may ...

Neuroimmune abnormalities may play a key role in fibromyalgia

Fibromyalgia is a complex disorder characterized primarily by chronic widespread pain, fatigue and other physical and cognitive symptoms. Although it affects millions of people worldwide, the underlying biological mechanisms ...

New tool maps how T cells move within tumors

Researchers at UT Southwestern Medical Center led a study to develop a computational method that reveals how immune cells navigate the complex environment inside tumors, offering insights that could inform future cancer therapies. ...