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Allergy and immunology news
How HIV hijacks a cellular 'gateway' to infect resting immune cells
Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells. The discovery challenges a decades-old assumption in HIV biology, and opens new ...
42 minutes ago
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Can AI forecast immune responses? New benchmark shows where predictions hold up and fail
Artificial intelligence is increasingly being used to help scientists accelerate drug discovery and search for new treatments. But for AI tools to work effectively, researchers need to know whether they can be validated and ...
2 hours ago
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FDA approves Dupixent for chronic spontaneous urticaria in young children
The U.S. Food and Drug Administration has approved Sanofi and Regeneron's Dupixent (dupilumab) for the treatment of children (aged 2 to 11 years) with chronic spontaneous urticaria (CSU).
16 hours ago
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Blocking stress signals could limit harmful inflammation after heart attack
After a heart attack, the body rapidly floods the injured heart with neutrophils—white blood cells that help repair damage but can also make it worse when too many arrive too quickly. New research from the University of Oklahoma ...
May 2, 2026
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Ticked off: How a bite can turn meat against you
Mammalian meat allergy (MMA) is one of the few known food allergies caused by an environmental trigger—a tick bite. In simple terms, MMA results in an allergic reaction to red meat, making it difficult or sometimes even impossible ...
May 1, 2026
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Why this CAR T advance matters: Complete remissions without chemotherapy at doses as low as 250,000 cells/kg
Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and mount potent anti-tumor responses. These properties make them an attractive candidate for next-generation ...
Apr 30, 2026
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For 30 years, doctors chased the wrong immune culprit behind this rare inflammatory disease
Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder. The study, published ...
Apr 30, 2026
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T cells secrete DNA to boost the immune system's cancer-fighting ability
Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell Medicine. The discovery ...
Apr 30, 2026
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Restoring protein recycling helps exhausted T cells fight tumors again
T cells are crucial components of our immune system, serving as critical protectors against infection and disease. But there are limits to their defensive capabilities. T cells are not inexhaustible protectors. Often, when ...
Apr 30, 2026
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Q&A: Why feeling sick may be important for surviving infection
Symptoms such as fatigue, loss of appetite, altered sleep, and social withdrawal are often treated as inconvenient side effects of infection. While some scientists have suggested that they may serve a protective function, ...
Apr 30, 2026
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Scientists recruit red blood cells to deliver genetic cargo with instructions to kill cancer
Scientists have developed a way to turn the body's own immune cells into cancer-fighting agents—without removing them from the body—by using red blood cells to deliver genetic instructions. Current CAR (chimeric antigen receptor) ...
How eating primes immune cells for future responses
Diets and healthy eating habits hold promise for preventing and treating diseases, but far less is known about acute effects on the immune system shortly after a meal.
Apr 29, 2026
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Your nose may be the gateway to a stronger immune system
At the moment, an influenza vaccine called FluMist is the only licensed intranasal vaccine approved for use in humans. The vaccine is administered through a spray of fluid in the nose, rather than with an injection.
Apr 29, 2026
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A natural molecule boosts CAR-T therapy and turns cold tumors hot
CAR-T cell therapy works well in blood cancers, but many patients still become resistant. A key reason is the presence of CAR-T regulatory T cells (CAR-Tregs), which weaken immune responses. Therefore, selectively targeting ...
Apr 29, 2026
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New dual-target drug may help overcome immunotherapy resistance in pancreatic cancer
Pancreatic ductal adenocarcinoma is one of the deadliest cancer types, with a five-year survival rate of 13%. There are only two treatment regimens available with limited efficacy. Pancreatic cancers do not respond to immunotherapy ...
Apr 29, 2026
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Why CAR T therapy works for some patients but fails for others may be getting clearer
Chimeric antigen receptor (CAR) T-cell therapy is one of oncology's most powerful ideas: Harvest a cancer patient's own immune cells, genetically engineer them to recognize tumor cells, multiply them in a laboratory and reinject ...
Apr 29, 2026
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Maternal antibodies in pregnancy may shape lifelong defenses against gum disease
A study from the Hebrew University of Jerusalem has identified a significant link between maternal care and lifelong oral health. Led by Prof. Avi-Hai Hovav and the DMD/Ph.D. student Reem Naamneh from the Faculty of Dental ...
Apr 29, 2026
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B-cell clusters inside kidneys mark faster diabetic disease progression, new maps reveal
A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells—specifically B cells—that are linked to faster disease progression. The findings ...
Apr 29, 2026
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How killer T cells attack tumors in 3D could sharpen future cancer immunotherapy
Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," where they release active ...
Apr 29, 2026
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Allergic rhinitis could lead to hearing impairment in children, teens
Allergic rhinitis (AR) could lead to hearing impairment in children/adolescents, according to a study published online April 9 in Frontiers in Pediatrics.
Apr 29, 2026
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Researchers deepen understanding of molecular pathways responsible for airway inflammation in asthma
Johns Hopkins Medicine researchers say they have identified molecular pathways controlled by the protein RhoA in club cells—a specialized population of epithelial cells that exclusively lines the inner and outer surfaces ...
Apr 29, 2026
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How the immune system battles lifelong viral infections acquired at birth
Millions of people worldwide carry viral infections they acquired at birth, often for life. For a long time it was assumed that the immune system hardly fights these pathogens. Researchers from the University of Basel show ...
Apr 28, 2026
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Why bone metastases resist treatment: New method identifies immune cells shielding tumors
Researchers at Baylor College of Medicine and collaborating institutions have developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary cause of death for most ...
Apr 28, 2026
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T cells, not B cells, are the culprit in kidney damage in lupus, study shows
Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells malfunction and produce antibodies that attack the body's own cells, tissues, and organs.
Apr 28, 2026
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Experimental drug offers new hope for celiac disease treatment
An experimental drug may in future provide a new form of protection for people with celiac disease. According to an international study led by the Universities of Oulu and Tampere, the drug dampens the harmful effects of ...
Apr 28, 2026
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