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Allergy and immunology news

Brain tumors hijack sugar metabolism to evade immune attack, study shows

Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published in the Proceedings ...

Implantable 'charging station' boosts fight against cancer

Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease. But many engineered immune cells lose strength quickly after they enter the body, especially inside tumors that actively ...

Math can tell you how to manage your eczema

Anyone with a chronic illness understands the struggle of living with a disease that is deeply unpredictable. Many such illnesses are characterized by long periods of remission broken up by sudden, debilitating flare-ups. ...

Here's what you need to know about cancer vaccine development

Cancer is the second-leading cause of death in the United States, accounting for over 613,000 fatalities in 2023, per the Centers for Disease Control. But the field of cancer vaccines, which can be used as a form of treatment, ...

Anchoring a key immune molecule makes T cells hit harder

Researchers at the Kennedy Institute of Rheumatology have found that physically resisting the formation of an immunological synapse actually promotes a stronger immune response. The findings could help explain how immune ...

How one flu virus can hamper the immune response to another

Prior exposure to one strain of influenza virus may weaken children's ability to mount an effective antibody response against their subsequent exposure to a different flu strain, according to a study led by Weill Cornell ...

UV air filters cut airborne asthma triggers, study finds

Ultraviolet air filters might help rid a person's home of asthma triggers, a new study suggests. Installing one type of UV air filter in heating, ventilation and air conditioning systems led to a more than twofold decrease ...

How a tick could help prevent diseases like MS and cancer

A team from the Monash University Biomedicine Discovery Institute has identified a tick-derived evasin that can bind to two major classes of chemokines, a discovery that is important for the development of therapeutics targeting ...

Paradigm shift in immune checkpoint biology

A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, providing new mechanistic ...

FDA approves Dupixent for allergic fungal rhinosinusitis

The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adult and pediatric patients aged 6 years and older with allergic fungal rhinosinusitis (AFRS) and a history of sino-nasal surgery.

Why our immune system remembers vaccinations for decades

Why can the human immune system often remember a vaccination for a whole lifetime? Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen have now investigated this question. ...

Lab-grown reservoir cells aim at HIV's last strongholds

A new study has overcome a long-standing challenge: how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure. Researchers ...

Engineered immune therapy could help fight brain aging

Researchers with the Knight Initiative for Brain Resilience have modified a well-known immune protein to spark the growth of new neurons, ease brain inflammation, and improve cognition in old mice. The findings, published ...