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Allergy and immunology news
Lab-grown tumors reveal immune cells capable of killing small cell lung cancer
Researchers have uncovered a previously overlooked immune cell that can recognize and kill small cell lung cancer, the most aggressive form of the disease globally. Published in Cancer Cell, the WEHI study found patients ...
14 hours ago
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How heart failure reshapes bone marrow to create inflammation-related immune memory
Heart failure (HF) is a condition in which the heart is not able to pump blood effectively. However, its effects go beyond pumping and circulation. HF is also known to cause a lasting form of innate immune memory in stem ...
15 hours ago
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Early nicotine exposure alters immune development and worsens later flu infections in mice
Exposure to nicotine during pregnancy and shortly after birth can have a lasting impact on a child's immune system and cause more severe respiratory infections later in life, a new study from researchers at the University ...
22 hours ago
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Antibody screening approach could speed development of immune-based cancer treatments
A team led by Harvard Medical School researchers at Beth Israel Deaconess Medical Center and Dana-Farber Cancer Institute has developed a faster way to identify and engineer cancer-fighting therapies.
17 hours ago
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Researchers identify key pathway that drives T-cell exhaustion in cancer immunotherapy
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, limiting their ability to keep tumors under ...
19 hours ago
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Cancer-promoting protein also helps engineered immune cells fight tumors in lab tests
Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.
Oct 14, 2026
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Reversible genetic switches could give cancer immunotherapy more precise control
A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute ...
Oct 14, 2026
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Abnormal antibodies that disrupt DNA repair could explain childhood cancer
A team of scientists in Norway has found evidence for a new mechanism for the development of cancer in children: They seem to produce an unusual amount of aberrant antibodies against the building blocks that make up the DNA ...
Oct 14, 2026
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Why autoantibodies may be linked to preterm birth risk in some women
A typical pregnancy lasts 40 weeks, but for about 1 in 10 pregnant women labor begins too soon. Premature or preterm birth is the leading cause of newborn deaths worldwide. Yet doctors have struggled to understand why preterm ...
Oct 14, 2026
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How food allergy risk changes as children grow
Food allergy is an important health concern in childhood, and knowing whether an allergy is likely to persist or disappear can affect medical decisions. Sensitization, however, is not the same as an allergy: specific IgE ...
Oct 14, 2026
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Immune system discoveries reveal how body balances defense, protection and repair
In the past, immune cells were all simply known as white blood cells. Nowadays, we know that there are T cells, B lymphocytes, macrophages, autoreactive T helper cells, microglia, Tregs and others. Together, they form a team ...
Oct 14, 2026
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Alcohol and the brain interact through immune cells, new research shows
A Cleveland Clinic research team studying alcohol and the brain discovered a new way that alcohol abuse can cause brain dysfunction and damage: through immune cells called microglia. The research also identified a potential ...
Oct 13, 2026
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Protein reins in intestinal inflammation by curbing an overactive immune signal
A preclinical study by researchers at UT Southwestern Medical Center has discovered how a protein called ZBTB44 helps prevent excessive immune activity that can cause inflammation in the colon, the main section of the large ...
Oct 13, 2026
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Scientists identify clues to making immunotherapy more effective against glioblastoma
Two new studies led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center provide new insight into how the immune system can successfully be activated against glioblastoma while revealing why these therapies ...
Oct 13, 2026
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Prime editing repairs immune disorder defect in patient's own blood stem cells
Some people are born with a defect in their genetic material that prevents their immune system from functioning properly. In people with a condition known as GATA2 deficiency, the body does not produce enough immune cells, ...
Oct 13, 2026
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Kidney biopsy maps reveal immune clusters that may keep inflammation going
Acute interstitial nephritis (AIN) is a condition characterized by inflammation that damages the kidney's tubules and surrounding tissue. Often resulting from an immune reaction to common medications—including antibiotics, ...
Oct 13, 2026
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AI tool reveals what attracts immune cells to tumors and what keeps them away
Researchers at The University of Texas MD Anderson Cancer Center and collaborating institutions in Texas developed an artificial intelligence (AI) model that helps explain how immune cells find their way to specific locations ...
Oct 13, 2026
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Enhanced CAR T-cell therapy shows early promise for B-cell cancers in first-in-human trial
Results from a Phase I clinical trial led by The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) show a possible way to improve therapy ...
Oct 13, 2026
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Human stem-cell model reveals a shared origin for tissue-resident macrophages
VIB researchers have developed a new human stem-cell-based model that recreates an early stage of immune-cell development and shows how a single progenitor population can give rise to specialized macrophages across different ...
Oct 13, 2026
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Tumor suppressor gene mutations trigger immune activation in early oral cancer
Head and neck squamous cell carcinoma (HNSCC) frequently develops in the oral and upper aerodigestive regions following chronic exposure to mutagenic factors such as tobacco, alcohol and betel nut. Alterations in the tumor ...
Oct 13, 2026
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Early gut microbes help the newborn immune system fight deadly infections, mouse experiments suggest
Babies are born with some immunity, but they do not have as many tools as adults to fight diseases. Exposure to pathogens helps build their immune repertoire, but it also leaves them vulnerable to infection because many immune ...
Everyday salon tools may expose hairdressers to allergy-triggering metals
When you think of people being exposed to occupational hazards, hairdressers don't come to mind. That may be why regulators often overlook the risks faced by people in this profession. Scientists have uncovered one such risk, ...
Females with autoimmune diseases 'less likely to be believed' than males and face longer diagnostic delays
Females with autoimmune diseases are significantly more likely than males to have their autoimmune disease misdiagnosed as a psychiatric or psychosomatic condition, according to a study of more than 6,600 patients.
Oct 12, 2026
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Rewilding urban home yards may benefit human microbiome and inflammatory response in just three months
Urbanization and biodiversity loss have reduced human contact with the diverse microbiomes found in natural environments. Exposure to environmental microbes supports the normal development and regulation of the immune system. ...
Oct 12, 2026
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Gut microbes help set the body's inflammatory response to vaccination
Vaccination is one of the most important tools for preventing infectious diseases and protecting public health. However, immune responses after vaccination vary dramatically from person to person: If you give many people ...
Oct 9, 2026
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