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Allergy and immunology news

Smart patch detects allergies before symptoms strike

A wearable device that alerts people with food allergies before a reaction begins has the potential to reduce life-threatening anaphylaxis and transform allergy management from reactive to preventive care. The AllergE patch ...

Immune cells retain a 'molecular memory' of their tissue location, study shows

A new AI-based method reconstructs spatial information about where immune cells were originally located in an organ, even after these cells have been removed from the tissue and analyzed individually. To accomplish this, ...

Painless skin patch offers new way to monitor immune health

Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly ...

How a tick could help prevent diseases like MS and cancer

A team from the Monash University Biomedicine Discovery Institute has identified a tick-derived evasin that can bind to two major classes of chemokines, a discovery that is important for the development of therapeutics targeting ...

Paradigm shift in immune checkpoint biology

A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, providing new mechanistic ...

FDA approves Dupixent for allergic fungal rhinosinusitis

The U.S. Food and Drug Administration has approved Dupixent (dupilumab) for the treatment of adult and pediatric patients aged 6 years and older with allergic fungal rhinosinusitis (AFRS) and a history of sino-nasal surgery.

Why our immune system remembers vaccinations for decades

Why can the human immune system often remember a vaccination for a whole lifetime? Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen have now investigated this question. ...

Lab-grown reservoir cells aim at HIV's last strongholds

A new study has overcome a long-standing challenge: how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure. Researchers ...

Engineered immune therapy could help fight brain aging

Researchers with the Knight Initiative for Brain Resilience have modified a well-known immune protein to spark the growth of new neurons, ease brain inflammation, and improve cognition in old mice. The findings, published ...

Optimizing CAR T-cell therapy to tackle solid tumors

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite prostaglandin E2 can block T cells—the killer cells of the immune system—in the vicinity of a tumor, ...

Rallying more T-cells to immunotherapy's fight against cancer

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...

Shining new light on how cytokines manage immune response

Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses molecules called cytokines to ...