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Allergy and immunology news
Previously unrecognized immune response could enhance defense against cancer
In a paradigm-breaking study, researchers have discovered a novel way the immune system, specifically T cells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications ...
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Local immune cell coordination in the lung reveals a new layer of defense
When a virus enters the lungs, the immune system has to react fast. The lung maintains its own community of immune cells capable of mounting a local defense on the spot. Researchers from the University of Basel now describe ...
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A protein may help revive exhausted T cells in cancer immunotherapy
Immunotherapy has been one of the most transformative treatments for cancer patients in recent decades, shifting the emphasis from the broad-spectrum approach of chemotherapy to prompting the immune system's boldest warriors—its ...
Immune cell 'bloodhounds' track cancer cells' unique metabolic signatures and eliminate tumors in mice
A technique that transforms immune cells into cancer-seeking bloodhounds may overcome a roadblock that has hampered immunotherapy for solid tumors, according to a new study by Stanford Medicine researchers. The approach equips ...
5 hours ago
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Autoantibodies implicated as drivers of long COVID in new study
A growing body of evidence suggests that long COVID (or post-COVID syndrome), a condition affecting more than 10% of people after a SARS-CoV-2 infection, may be driven by the immune system turning against the body. Now, new ...
5 hours ago
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Dual immune response may keep HIV in check without medication
Imagine a game of chess where your opponent's king is in check. It cannot move, but the game is not over—the piece remains on the board. This is how the body might control HIV on its own: The virus would be contained and ...
23 hours ago
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Existing medication can restore HIV-affected immune cells
HIV exhausts the body's immune system by overactivating it, despite effective antiviral treatment. Researchers from Linköping University in Sweden have conducted cell studies showing that an existing medication restores ...
Mar 23, 2026
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Scientists pinpoint a skin alarm system pathway that links local damage to systemic immune responses
Skin, our largest organ, acts as a protective barrier against pathogens that try to invade our bodies while constantly monitoring for potential threats. In the skin's outermost layer, the epidermis, reside keratinocytes, ...
Skin's immune response could be key to fighting dengue
Dengue, a mosquito-borne viral disease, infects an estimated 390 million people and causes around 20,000 deaths worldwide each year. New research suggests the skin is a major site of immune surveillance for dengue. The findings ...
Mar 23, 2026
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Welcome to allergy season. Here's how to protect yourself
Allergy season can be miserable for tens of millions of Americans when trees, grass, and other pollens cause runny noses, itchy eyes, coughing and sneezing.
Mar 23, 2026
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HPV-positive cancers hide from the immune system, but blocking a single protein could make the tumors treatable
A team of scientists at Henry Ford Health + Michigan State University Health Sciences have uncovered a mechanism that allows certain head and neck cancers to hide from the immune system, a discovery that could change how ...
Mar 22, 2026
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Why do 'sleep attacks' happen? Study points to an autoimmune trigger in narcolepsy
Researchers at the Netherlands Institute for Neuroscience have found evidence that type-1 narcolepsy, a condition known for its "sleep attacks," is caused by the body's own immune system. The work is published in the journal ...
Mar 21, 2026
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Why some people naturally control HIV even after stopping therapy—and how we can leverage that to treat others
For millions of people living with HIV, a daily regimen of medications is a lifelong necessity. If they stop taking the drugs—commonly referred to as antiretroviral therapy—the virus usually rushes back within weeks. ...
Mar 20, 2026
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An immune signaling pathway drives pain in arthritis, researchers discover
Rheumatoid arthritis is a chronic autoimmune disease that affects millions of people worldwide. This disease prompts the immune system to mistakenly attack body tissues, particularly joints, leading to inflammation, swelling, ...
Stress-activated pathway reveals how nervous system contributes to eczema flare-ups
The mystery of how stress exacerbates atopic dermatitis, more commonly known as eczema, may be closer to being understood. A new study published in the journal Science has identified a specific nerve pathway that helps explain ...
Why endometriosis should be classified as a whole‑body inflammatory disorder
Endometriosis is a painful, debilitating condition affecting 10% of women worldwide. It occurs when tissue similar to the lining of the uterus (known as lesions) grows elsewhere in the body—usually within the pelvis.
Mar 20, 2026
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Switching from milk to solid food in early life helps reprogram the gut's immune defenses, researchers find
According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning or switching from milk to solid food in early life doesn't just change what babies eat, it helps ...
Mar 19, 2026
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New 'fishhook' bonds help T cells stick longer to prostate cancer cells
UCLA and Stanford Medicine researchers, in collaboration with scientists from the University of Utah and Columbia University, have engineered a new class of supercharged T cells that are stronger, longer-lasting, and more ...
Mar 19, 2026
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AI helps to evaluate skin lesions in rare disease more accurately
There is a promising new drug for the rare disease mastocytosis, which is associated with skin lesions, among other things. Researchers at the University of Basel have now been able to use artificial intelligence to quantitatively ...
Mar 19, 2026
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Masked T‑cell engagers: Cancer immunotherapies for the future?
A new immunotherapy drug has demonstrated early promise in a recent prostate cancer clinical trial. The drug, called VIR-5500, is a "masked T-cell engager." This type of immunotherapy ignites our own immune arsenal to fight ...
Mar 19, 2026
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Scientists track real-time signaling in T cell activation to show how the immune system defends against threats
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the earliest moments of ...
Long dismissed in adult health, the thymus may be critical for longevity and cancer treatment
Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. ...
Mar 18, 2026
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Scientists create cancer-fighting immune cells right in the body
For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient's immune cells, ship them to a specialized facility where ...
Mar 18, 2026
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Cellular stress signal found to drive immune exhaustion and weaken cancer therapy
Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
Mar 18, 2026
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Cancer drug protein target may also help fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX). Published in Cell Reports, the study found that Programmed Death-Ligand ...
Mar 18, 2026
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