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Allergy and immunology news
'Off the shelf' immunotherapy could get a lift from gene-edited natural killer cells
Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they've been trying to engineer a cell that's effective against solid tumors, which account for the vast majority ...
12 hours ago
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Differing immune responses in infants may explain increased severity of RSV over SARS-CoV-2
Young infants hospitalized with respiratory syncytial virus (RSV) often become much sicker than those infected with SARS-CoV-2, the virus that causes COVID-19. In a study published in Science Translational Medicine, scientists ...
5 hours ago
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Why eczema often starts in childhood: New clues point to early immune 'overreaction'
A team of researchers at the Icahn School of Medicine at Mount Sinai, Weill Cornell Medicine, and other institutions have uncovered a key biological explanation for why eczema so often starts in childhood. The study, in young ...
13 hours ago
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Lab-grown reservoir cells aim at HIV's last strongholds
A new study has overcome a long-standing challenge: how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure. Researchers ...
Feb 24, 2026
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Two lipids that help switch on STING open doors in fight against autoimmune disorders and cancer
UT Southwestern Medical Center researchers have identified two lipids that work together with a quintessential protein known as stimulator of interferon genes (STING) to launch an immune response in the human body. Their ...
Feb 24, 2026
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Why our immune system remembers vaccinations for decades
Why can the human immune system often remember a vaccination for a whole lifetime? Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen have now investigated this question. ...
Feb 24, 2026
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Engineered immune therapy could help fight brain aging
Researchers with the Knight Initiative for Brain Resilience have modified a well-known immune protein to spark the growth of new neurons, ease brain inflammation, and improve cognition in old mice. The findings, published ...
Feb 24, 2026
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Universal vaccine to treat colds, flu and COVID developed, and a new study suggests it just might work
Vaccines have traditionally worked by teaching the immune system to recognize a specific virus or bacterium—in effect, showing it a wanted poster for a single suspect. But what if one vaccine could protect against dozens ...
Feb 24, 2026
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Not just drainage: Dural venous sinuses actively regulate brain immunity and fluid flow, study finds
National Institute of Neurological Disorders and Stroke investigators at the National Institutes of Health traced meningeal immune activity to dural venous sinuses that actively constrict and dilate, exchange fluid across ...
Study reveals why some immune disorders trigger severe food allergies, and others don't
A new study has shed light on why patients with certain rare immune disorders develop severe, food-triggered allergic reactions while others with similar diagnoses do not. The findings, published in the Journal of Experimental ...
Feb 23, 2026
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A silent signaling network deep in the gut protects against inflammatory intestinal disorders, scientists find
Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem cells lining the gut wall are not just rebuilding tissue—they are listening and signaling. When ...
Why chronic pain lasts longer in women: Immune cells offer clues
Chronic pain lasts longer for women than men, and new research suggests differences in hormone-regulated immune cells, called monocytes, may help explain why.
Feb 20, 2026
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Newly found immune cells link strep throat to psoriasis
A common strep throat infection can trigger guttate psoriasis by altering the behavior of key immune cells, according to a new study from Karolinska Institutet published in eBioMedicine. The findings suggest how an infection ...
Feb 20, 2026
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Engineered CAR-NK cells appear more 'attack-ready'
Researchers at the Ribeirao Preto Blood Center and the Center for Cell-Based Therapy (CTC) conducted a study using the NK-92 cell line to test new models of chimeric antigen receptors (CARs) with specific costimulatory domains, ...
Feb 20, 2026
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Gene variants help explain why food allergies run in families
People often remark that allergies run in their family, but the genetic causes have remained unclear. Previous food allergy genetic research has relied upon broad but surface-level methods called genome-wide association studies.
Feb 20, 2026
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Epstein-Barr: The virus nearly everyone carries and its possible role in MS
Over 95% of the world's adult population is infected with Epstein-Barr virus (EBV), but most people never realize it. The infection often causes few symptoms and then stays in the body for life.
Feb 20, 2026
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Study reveals a specific genetic mismatch linked to life-threatening transplant complications
Umbilical cord blood transplantation has transformed the treatment options for patients with blood cancers and other life-threatening hematologic disorders, particularly when matched donors are unavailable. While cord blood ...
Feb 20, 2026
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Discovery could improve immune checkpoint inhibitor safety
For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar brand names. However, ...
Feb 20, 2026
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Study finds immune signature linked to treatment-resistant myasthenia gravis
Myasthenia gravis (MG) is a rare autoimmune disease in which the immune system attacks the connection between nerves and muscles. This attack causes muscle weakness that can affect vision, movement, speech, swallowing, and ...
Feb 20, 2026
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Closing in on a universal vaccine: Nasal spray protects mice from respiratory viruses, bacteria and allergens
In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail—and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators ...
Feb 19, 2026
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Mechanism behind immunotherapy resistance in lung cancer identified
Mayo Clinic researchers and collaborators have identified a previously unrecognized way lung tumors weaken the immune system, helping explain why many patients do not respond to immunotherapy and pointing to a potential new ...
Feb 19, 2026
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Remote-controlled CAR-T cells use venetoclax to disengage from tumors
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers. Yet, despite their promise, CAR-T cells do ...
Feb 19, 2026
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Oral vaccine strategy used modified bacterium to combat colorectal cancer
A research team investigating the use of the bacterium Listeria monocytogenes against colorectal cancer has discovered a way to build a modified version of Listeria as an oral vaccine to prime the immune system directly within ...
Feb 19, 2026
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Macrophages need constant reminders to retain memories of prior infections, researchers discover
Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling molecules left behind ...
Feb 18, 2026
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Missing ANGPTL4 gene in mice reprograms immunity, shielding against gut inflammation
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. ...
Feb 18, 2026
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