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Allergy and immunology news
Reversing T cell exhaustion improves effectiveness of myeloma immunotherapies
Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma. In two ...
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Researchers discover new clues to delaying type 1 diabetes
Thomas Delong, Ph.D., moved to Colorado from Germany two decades ago intent on one thing: understanding the origin of type 1 diabetes (T1D) and finding ways to stop it. Diagnosed at age 12 with the disease that affects 9.5 ...
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How lungs balance defense and damage by tuning responses to deeper threats
Barrier organs that form boundaries between the body and the outside environment, such as the lungs, skin, and intestines, face a difficult balancing act. They must respond quickly to threats such as infection, but they also ...
May 16, 2026
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Neuronal hyperactivity triggers severe autoimmune brain disorder, researchers discover
In a condition known as "IgLON5 encephalitis," the immune system mistakenly attacks cells in the brain. This leads to brain inflammation and neuronal damage, which can manifest as sleep disturbances, cognitive impairment, ...
May 15, 2026
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Friendly skin bacteria shut down inflammatory driver of eczema
Friendly skin bacteria could hold the key to stopping eczema in its tracks, according to a breakthrough by a team of UK and Japanese scientists. Their new study reveals harmless microbes living on our skin release powerful ...
May 14, 2026
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The liver's immune cells might be the key to curing hepatitis B
Fifteen years ago, doctors in Europe noticed a remarkable thing happening in people with chronic hepatitis B infections. When patients went off their medications, the virus started to come back—and then some of the patients ...
May 14, 2026
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Lab-designed molecule offers hope for celiac disease sufferers
A research project led by the Institute for Research in Nutrition and Food Safety (INSA) and the Faculty of Pharmacy and Food Sciences at the University of Barcelona, together with the Molecular Biology Institute of Barcelona ...
May 14, 2026
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Immune system overreaction linked to deadly flu in pregnancy
In most people, influenza stays in the upper respiratory tract—mainly the nose—and clears without spreading further. But during pregnancy, the virus can extend beyond the lungs into the cardiovascular system, increasing the ...
May 14, 2026
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Hidden genetic defect linked to Kaposi sarcoma for the first time
A new study has uncovered a genetic cause that may explain why some people develop Kaposi sarcoma despite having no apparent immune deficiency. The rare cancer, which forms in the cells lining blood vessels, is caused by ...
May 14, 2026
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Researchers identify molecule linked to treatment-resistant inflammatory bowel disease
Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly ...
May 13, 2026
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Breast cancer cells with doubled genomes may dodge immunotherapy by turning off key immune signals
An epigenetic mechanism by which tumors manage to hide from the body's immune defenses has just been described by an international scientific team led by the University of Liège and the Dana-Farber Cancer Institute. These ...
May 13, 2026
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A new approach to cancer vaccination yields more powerful T cells
MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines—an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious diseases.
May 13, 2026
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Future cancer therapy could use immunity to clean up damaged DNA by modulating AUF1
Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the authors of a new paper demonstrated how the downregulation of AUF1 impairs DNA repair, followed ...
May 13, 2026
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New guideline aims to reduce severe allergic reactions to epilepsy drugs
Researchers from the Center of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx) have published a new prescribing guideline aimed at reducing the incidence of serious allergic reactions to common ...
May 13, 2026
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Genes linked to neuronal communication appear altered in immune cells of patients with depression
Neurons and white blood cells differ greatly in shape, function, and location within the body. However, researchers at the University of Sao Paulo (USP) in Brazil discovered that certain genes are equally dysregulated in ...
May 12, 2026
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Food allergy researchers predict oral food challenge tests as an obstacle to future food allergy trials
A new international perspective led by UNC School of Medicine researchers highlights that oral food challenges, historically considered essential to food allergy clinical trials, are now limiting who can participate and threatening ...
May 12, 2026
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Data hidden in tuberculosis screening tests shed light on patients' overall mortality
Scientists have long known that the immune system plays a key role in aging. As people age, they have weaker responses to vaccination, greater risks of infection and higher levels of inflammation. A new study led by UCLA ...
May 12, 2026
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A common mutation linked to autoimmune diseases may protect people from viral infections
New research from the University of Kansas shows a "risk gene" linked to higher odds of developing autoimmune diseases such as diabetes or lupus may also provide a survival advantage fighting viral infections like coronavirus. ...
May 11, 2026
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Scientists discover hidden switch in immune cells that helps the body kill deadly fungus
Scientists at the University of East Anglia (UK) have contributed to discovering a "control switch" inside our immune cells that helps the body destroy dangerous fungal infections. Researchers found that a protein called ...
May 11, 2026
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Allergy treatment shifts toward precision medicine with tailored immunotherapy, new guidance shows
Until recently, allergy treatment was largely based on average treatment schemes. A patient with pollen allergy would receive a similar therapy to others with the same diagnosis. Today, this model is beginning to change. ...
May 8, 2026
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Immunologist's lab demonstrates the power of B cells to gather and defend organs against cancer
Creativity and curiosity have always been central to the work of Joshua Moreau, Ph.D., an immunologist whose work at Oregon Health & Science University sits at the intersection of harnessing the immune system; delving into ...
May 8, 2026
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Hidden sex differences may explain why lupus strikes women far more often
Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and UNSW Sydney helps explain why women are significantly more likely to be diagnosed with an autoimmune disease—a condition where ...
May 7, 2026
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Study identifies new strategy to overcome immunotherapy resistance in colorectal cancer
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have identified a promising new strategy to overcome resistance to immunotherapy in colorectal cancer, one of the leading ...
May 7, 2026
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Scientists take crucial step in developing world's first measles treatment
Scientists at La Jolla Institute for Immunology (LJI) are the first in the world to characterize human antibodies capable of neutralizing measles virus. These antibodies bind to key sites on measles virus and prevent the ...
May 7, 2026
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Chronic bowel disease involves multiple types of inflammation happening at once, study reveals
Chronic immune diseases are shaped by multiple inflammatory processes happening at the same time, each in different parts of the tissue. This finding from Karolinska Institutet, published in the journal Immunity, is based ...
May 7, 2026
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