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Allergy and immunology news
Researchers trace antibodies behind severe viral infections
Some people carry antibodies that block the body's early defenses against viruses, increasing their risk of developing severe illnesses such as severe COVID-19. Researchers at Karolinska Institutet have now identified the ...
Nov 3, 2026
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Gut immune cells sustain pain even without inflammation through newly identified signaling pathway
People with inflammatory bowel conditions such as ulcerative colitis often suffer from severe, long-lasting gut pain that lingers even after signs of inflammation are gone. Such abdominal pain can significantly affect one's ...
Human dengue trial reveals how immune memory can help—or backfire
Spread through the bite of Aedes mosquitoes, dengue is a viral infection that can cause anything from mild fever, flu-like symptoms and joint pain to a severe form known as dengue hemorrhagic fever. What makes dengue particularly ...
How the immune system gets better at detecting pathogens
B cells, a type of white blood cell, protect our bodies by producing antibodies that recognize and bind to invaders like bacteria and viruses. After an infection, B cells undergo rapid mutations in the genes that encode antibodies. ...
Nov 2, 2026
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How an innate immune protein can control cholesterol, tumor growth and response to cancer therapy
Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and ...
Nov 2, 2026
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Reversing radiation-activated immune suppression in cancer
Researchers at the University of Chicago have identified a mechanism to make immune cells reprogrammed by radiation therapy attack tumors rather than protect them. The study, published in Cancer Cell, shows that radiation ...
Oct 31, 2026
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Checkpoint immunotherapy reshapes immune environment in lymph nodes after melanoma reaches them
A new study from Mayo Clinic suggests checkpoint immunotherapy may reshape the immune environment within lymph nodes after melanoma has spread to them. Researchers found that treatment reorganized several types of immune ...
Oct 30, 2026
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How one of the body's own proteins drives the vicious cycle of inflammation in vaginal yeast infections
Up to three-quarters of all women will experience a genital yeast infection at least once in their lives. Recurrent infections, in particular, can significantly impair quality of life. The typical symptoms—such as itching, ...
Oct 30, 2026
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Not all antihistamines are the same—and some may affect your brain more than you think
Millions of people take antihistamines for allergies, but some of these medicines can make you sleepy, slow your reactions and affect your concentration. Others are much less likely to have these effects. Knowing the difference ...
Oct 30, 2026
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Specialized immune cells may help skin nimbly respond to changing environmental conditions
As the steadfast protector of the body's interior, the skin must be able to swiftly respond to stressors from the outside world and then return to a steady state to maintain everyday operations. Coordinating that agile response ...
Oct 29, 2026
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Immune changes linked to diabetes could guide development of new cancer treatments
New research in The Journal of Immunology uncovers how high blood sugar (hyperglycemia) and type 1 diabetes (T1D) may protect against certain cancers like melanoma, breast and colon cancer. T1D has been associated with a ...
Oct 29, 2026
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Could a few bad dietary choices worsen your next immune response?
Scientists have long known that diet shapes the immune system. Now, a UC San Francisco team has found that even a brief dietary change can substantially change how the body responds to skin irritation, at least in mice.
Oct 29, 2026
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Immune system protein is a cancer killer on its own, new study shows
For decades, scientists have known that a protein made by T cells and natural killer (NK) cells in the immune system, called perforin, can kill tumor cells by punching a hole in the cell wall and injecting proteases called ...
Oct 29, 2026
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COMPASS pathway enables regulatory T cells to prevent devastating autoimmune responses to gut bacteria
Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance. ...
Oct 29, 2026
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How common dietary fats can aggravate chronic itch
A team of researchers has found that a breakdown product from a commonly consumed fat can bind to a receptor associated with psoriatic itch and inflammation. By blocking the receptor, the researchers saw a reduction in psoriatic ...
Oct 29, 2026
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Known for preventing cancer, p53 could also help immune cells fight it
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a new strategy to make cancer-fighting immune cells stronger and potentially longer-lasting, a discovery that could help improve the effectiveness ...
Oct 29, 2026
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Researchers identify critical window for boosting immunotherapy response in prostate cancer
Researchers at Roswell Park Comprehensive Cancer Center have shown that hormone-blocking therapies commonly used to treat prostate cancers temporarily activate the body's immune response before those immune effects begin ...
Oct 29, 2026
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Restoring an amino acid can diminish age-related inflammation
Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system—the body's first line of defense—leading to what is known as inflammaging, functional ...
Oct 28, 2026
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Mutated immune cells raise red flags in lupus
Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds.
Oct 28, 2026
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Preclinical research shows macrophages can be programmed to fight solid cancer tumors
One person dies every 50 seconds in the U.S. from cancer, and an estimated 39% of people in the country will develop cancer during their lifetime. Survival rates have improved in recent decades from innovations and combinations ...
Oct 28, 2026
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Common nutritional supplement may boost psoriasis treatment, small patient trial suggests
Researchers in China have discovered that the vitamin B5 derivative pantethine limits the activity of immune cells that are key contributors to autoimmune diseases such as psoriasis. The study, published in the Journal of ...
Oct 27, 2026
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Needle-free Strep A vaccine triggers local and bodywide immune responses in mice
New research by the Medicines and Healthcare products Regulatory Agency (MHRA) in partnership with the GSK Vaccines Institute for Global Health has moved a vaccine against the highly contagious group A streptococcus bacterium ...
Oct 27, 2026
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Previously unrecognized immune cells may drive harmful blood vessel growth in blinding eye diseases
A Northwestern Medicine study has identified a previously unrecognized population of immune cells that appears to fuel harmful blood vessel growth in multiple blinding eye diseases, according to the study published in the ...
Oct 26, 2026
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