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Allergy and immunology news
Checkpoint immunotherapy reshapes immune environment in lymph nodes after melanoma reaches them
A new study from Mayo Clinic suggests checkpoint immunotherapy may reshape the immune environment within lymph nodes after melanoma has spread to them. Researchers found that treatment reorganized several types of immune ...
23 hours ago
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How one of the body's own proteins drives the vicious cycle of inflammation in vaginal yeast infections
Up to three-quarters of all women will experience a genital yeast infection at least once in their lives. Recurrent infections, in particular, can significantly impair quality of life. The typical symptoms—such as itching, ...
21 hours ago
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Not all antihistamines are the same—and some may affect your brain more than you think
Millions of people take antihistamines for allergies, but some of these medicines can make you sleepy, slow your reactions and affect your concentration. Others are much less likely to have these effects. Knowing the difference ...
22 hours ago
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Could a few bad dietary choices worsen your next immune response?
Scientists have long known that diet shapes the immune system. Now, a UC San Francisco team has found that even a brief dietary change can substantially change how the body responds to skin irritation, at least in mice.
Oct 29, 2026
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How common dietary fats can aggravate chronic itch
A team of researchers has found that a breakdown product from a commonly consumed fat can bind to a receptor associated with psoriatic itch and inflammation. By blocking the receptor, the researchers saw a reduction in psoriatic ...
Oct 29, 2026
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Immune system protein is a cancer killer on its own, new study shows
For decades, scientists have known that a protein made by T cells and natural killer (NK) cells in the immune system, called perforin, can kill tumor cells by punching a hole in the cell wall and injecting proteases called ...
Oct 29, 2026
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Specialized immune cells may help skin nimbly respond to changing environmental conditions
As the steadfast protector of the body's interior, the skin must be able to swiftly respond to stressors from the outside world and then return to a steady state to maintain everyday operations. Coordinating that agile response ...
Oct 29, 2026
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COMPASS pathway enables regulatory T cells to prevent devastating autoimmune responses to gut bacteria
Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance. ...
Oct 29, 2026
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Known for preventing cancer, p53 could also help immune cells fight it
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a new strategy to make cancer-fighting immune cells stronger and potentially longer-lasting, a discovery that could help improve the effectiveness ...
Oct 29, 2026
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Immune changes linked to diabetes could guide development of new cancer treatments
New research in The Journal of Immunology uncovers how high blood sugar (hyperglycemia) and type 1 diabetes (T1D) may protect against certain cancers like melanoma, breast and colon cancer. T1D has been associated with a ...
Oct 29, 2026
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Researchers identify critical window for boosting immunotherapy response in prostate cancer
Researchers at Roswell Park Comprehensive Cancer Center have shown that hormone-blocking therapies commonly used to treat prostate cancers temporarily activate the body's immune response before those immune effects begin ...
Oct 29, 2026
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Restoring an amino acid can diminish age-related inflammation
Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system—the body's first line of defense—leading to what is known as inflammaging, functional ...
Oct 28, 2026
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Mutated immune cells raise red flags in lupus
Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds.
Oct 28, 2026
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Preclinical research shows macrophages can be programmed to fight solid cancer tumors
One person dies every 50 seconds in the U.S. from cancer, and an estimated 39% of people in the country will develop cancer during their lifetime. Survival rates have improved in recent decades from innovations and combinations ...
Oct 28, 2026
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Common nutritional supplement may boost psoriasis treatment, small patient trial suggests
Researchers in China have discovered that the vitamin B5 derivative pantethine limits the activity of immune cells that are key contributors to autoimmune diseases such as psoriasis. The study, published in the Journal of ...
Oct 27, 2026
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Needle-free Strep A vaccine triggers local and bodywide immune responses in mice
New research by the Medicines and Healthcare products Regulatory Agency (MHRA) in partnership with the GSK Vaccines Institute for Global Health has moved a vaccine against the highly contagious group A streptococcus bacterium ...
Oct 27, 2026
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Previously unrecognized immune cells may drive harmful blood vessel growth in blinding eye diseases
A Northwestern Medicine study has identified a previously unrecognized population of immune cells that appears to fuel harmful blood vessel growth in multiple blinding eye diseases, according to the study published in the ...
Oct 26, 2026
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Personalized cancer vaccine plus immunotherapy reduces melanoma recurrence after surgery
Adding a personalized mRNA-based cancer vaccine to immunotherapy after surgery for high-risk melanoma reduced the risk of recurrence or death by 42%, according to results from the phase 3 INTerpath-001 trial presented at ...
Oct 26, 2026
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Exploring the potential of immunotherapy in early-stage triple-negative breast cancer
Triple-negative breast cancers, which are more frequently diagnosed in younger women, are a subtype of breast tumor characterized by the absence of hormone receptors and HER2 overexpression. As a result, they do not respond ...
Oct 26, 2026
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Can psychedelics soothe an overactive immune system? New meta-analysis investigates
The same substances that can alter perception and shift moods are now drawing scientific interest for their potential therapeutic abilities. Researchers across the globe are investigating whether psychedelics, such as psilocybin ...
Investigational vaccine generates immune response to KRAS mutations in pancreatic cancer study
An investigational vaccine helped the immune system recognize and respond to mutations that drive most pancreatic cancers, according to results from a randomized phase 2 clinical trial led by Mayo Clinic researchers. The ...
Oct 24, 2026
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Study identifies key drivers of microbiome-linked cancer immunotherapy side effect
Scientists at the University of Pittsburgh uncovered the unstable immune cells that can cause up to 40% of immunotherapy patients to experience serious side effects and showed that diet and microbiome composition influence ...
Oct 22, 2026
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Research finds bariatric surgery can restore immune cell function affected by obesity
New Maynooth University (MU) research led by the Department of Biology's Dr. Ciara Flynn, working within the research group of Professor Andrew Hogan at the Kathleen Lonsdale Institute for Human Health Research, has found ...
Oct 22, 2026
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HIV genetic remnants can alter immune cells in ways that may promote viral persistence
HIV may be suppressed by antiretroviral therapy, but its genetic material remains in the body. New research by scientists at the Leibniz Institute of Virology (LIV) in Hamburg suggests that some of these viral remnants may ...
Oct 21, 2026
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T cell survival protein controls gene activity, offering clues to HIV persistence
A prominent protein on most human cells may be key to unlocking the code that makes humans susceptible to pathogenic bacteria and viruses, including human immunodeficiency virus (HIV), according to a new study published in ...
Oct 21, 2026
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