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Allergy and immunology news
Scientists in France pinpoint why STING pathway hasn't been harnessed for cancer therapy yet
Deep within the cellular landscape, a quiet failure was taking place, impeding a potentially successful form of cancer treatment. For years, scientists hoped an essential part of the innate immune system that detects foreign ...
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Hidden immune cells in the lung could lead to better flu vaccines
Influenza continues to cause major illness each year in the United States, leading to more than 35,000 deaths annually. Children, older adults, pregnant individuals, people with weakened immune systems and those with chronic ...
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Clues to longevity may reside in the genomes of long-lived bats
The secret to a long life may lie in the genomes of the longest-lived mammals for their size: bats. That idea captivated Juan Manuel Vazquez when he was a graduate student at the University of Chicago, but at the time he ...
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Fractional exhaled nitric oxide elevated in pediatric chest tightness-variant asthma
Children with chest tightness variant asthma (CTVA) have higher fractional exhaled nitric oxide (FeNO) levels and lower measures of small airway function, according to a study published online Aug. 10 in Frontiers in Pediatrics.
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22 million human immune cells help decode context-dependent gene circuits
Scientists from Gladstone Institutes, UC San Francisco and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding ...
Aug 28, 2026
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New RNA vaccine strategy aims to build broader immunity against mutating viruses
New research by Malaghan's Connor Laboratory, published in PNAS, shows how directing the immune system toward conserved areas of the COVID virus and its many variants using RNA technology could be a significant step toward ...
Aug 28, 2026
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Three shifting immune states in sepsis could explain why treatments miss their window
Researchers have mapped how the immune response in people with sepsis changes over time. The work, led by King's College London, could help pave the way for treatments that target the specific parts of the immune system that ...
Aug 28, 2026
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Immune cells that drive harmful autoantibody responses after COVID-19 identified
When the immune system encounters a virus, it produces antibodies designed to recognize and eliminate the invader. But in some people infected with SARS-CoV-2, the virus that causes COVID-19, the immune response goes awry, ...
Aug 28, 2026
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Schizophrenia and mood disorders show different innate immune signatures, analysis finds
A team involving researchers from Wroclaw Medical University analyzed studies of people with schizophrenia spectrum disorders and mood disorders, including depression and bipolar disorder. They found that the two groups showed ...
Aug 27, 2026
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Researchers develop scalable method to generate key immune cells for cancer therapy
Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells ...
Aug 27, 2026
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Why do some people react so badly to mosquito bites? The answer lies in mosquito saliva
Two people spend an evening in the same garden and receive roughly the same number of mosquito bites. By morning, one barely notices them—while the other is covered in large, swollen, intensely itchy welts that linger for ...
Aug 27, 2026
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Male sex hormones may protect lungs from asthma by boosting nerve connections
The differences in male and female sex hormones are most evident during growth, puberty and reproduction, when they help shape how the body develops and functions. Beyond their more visible effects, these chemical messengers ...
Gut tissue may retain inflammatory 'memory' for more than a year
Every three to five days, the layer of cells lining our intestines is completely renewed—the fastest turnover rate in the human body. Such rapid regeneration is an absolute necessity for tissue that endures constant mechanical ...
Aug 26, 2026
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How much the immune system sees may shape how well we fight infections
Why does the same infection cause only mild symptoms in one person but more serious disease in another? A new study led by the HUN-REN BRC Szeged Momentum Systems Immunology Research Group, together with several international ...
Aug 26, 2026
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Experimental Zika vaccine reveals T cells can drive protection without antibodies
Zika virus has been spreading for decades, but it first grabbed worldwide headlines in 2016. That February, with an outbreak sweeping the Americas, the World Health Organization (WHO) declared the surge in Zika-linked birth ...
Aug 26, 2026
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Immune responses to urinary tract infection linked to birth outcomes
A study published in Science Translational Medicine shows that the increased risk of preterm birth associated with urinary tract infection (UTI) is linked to the body's immune response to the infection rather than to the ...
Aug 26, 2026
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AI and proteomics uncover seven blood proteins linked to vasculitis remission
Vasculitis is a disease in which the immune system mistakenly attacks blood vessel walls, causing them to become inflamed. If left untreated, the rare disease can severely damage organs, including the kidneys and lungs. Physicians ...
Aug 26, 2026
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How DNA folding controls immune gene activity in T cells
A new study by researchers at the Perelman School of Medicine at the University of Pennsylvania reveals that the three-dimensional folding of DNA at a key genetic locus helps determine when two related immune genes, Ets1 ...
Aug 26, 2026
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'Teacher cells' coated with tumor fragments train T cells to attack cancer in lab tests
The immune system possesses legions of T cells that, if primed, could hunt down and destroy tumors. Now, a UC San Francisco team has invented a way to do this by combining immune cells grown in the lab with samples from a ...
Aug 25, 2026
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Removing immune 'brake' improves CAR T-cell therapy for pediatric bone cancer
Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma. There is a great clinical ...
Aug 25, 2026
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Additional transfusion risk emerges for patients with tick-borne alpha-gal syndrome, beyond meat allergy
A new multi-institutional study led by researchers at Dartmouth Health and Geisel School of Medicine at Dartmouth suggests that alpha-gal syndrome, a tick-borne disease that can result in a chronic allergy to meat and animal ...
Aug 25, 2026
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New oral nanomedicine boosts effectiveness of cancer immunotherapies
Immune checkpoint blockade is a form of cancer treatment that works by releasing the natural brakes on the immune system, allowing T cells to find and destroy cancer cells. Although it has transformed cancer immunotherapy, ...
Aug 25, 2026
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Restoring aging T cell function to make them effective at fighting cancer
In a new study, Mass General Brigham researchers explore the causes of immune aging, a barrier to successful cancer immunotherapy, and identify a gene that may serve as an age-related prognostic marker and potential target ...
Aug 25, 2026
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Researchers map the development and behavior of B cells in melanoma
Researchers have created one of the most detailed maps to date of how white blood cells called B cells develop and behave inside melanoma tumors, a type of skin cancer. The study, led by King's College London and published ...
Aug 25, 2026
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Pollen season poses greater risk for people with COPD
Increased exposure to pollen negatively affects the lung function of people with chronic obstructive pulmonary disease (COPD), according to a new study in the July 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal ...
Aug 25, 2026
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