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Immunology news
Genetics
Gene therapy delivers lasting immune protection in children with rare disorder
An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare ...
12 hours ago
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Diseases, Conditions, Syndromes
Checkpoint inhibitor promotes tissue repair, offering hope for chronic wound treatment
Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing. This finding could help advance ...
15 hours ago
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Immunotherapy approach offers hope for long-term HIV control without daily medication
HIV remains a major global health issue, affecting nearly 40 million people worldwide. Current treatments, known as antiretroviral therapy (ART), are highly effective at suppressing the virus and preventing illness, but they ...
20 hours ago
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Immune cell subtype in multiple sclerosis patients may enable targeted treatment
Multiple sclerosis, which affects around one in 500 people in Switzerland, is an autoimmune disease in which immune cells attack the central nervous system, causing irreversible damage. Current treatments involve blocking ...
16 hours ago
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Conversion of IgG antibodies to IgM broadens antibacterial activity
Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can significantly broaden their ability to recognize and bind multiple human-relevant bacterial pathogens. The ...
17 hours ago
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SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...
11 hours ago
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Novel combination therapy shows promise for aggressive lymphoma resistant to immunotherapy
A study published in Cancer Discovery finds that combining an epigenetic therapy with an anti-PD-1 antibody, which uses the body's natural response to viral infections, shows promising results in patients with relapsed or ...
Oct 15, 2025
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Human liver organoid platform can predict immune-mediated drug toxicity
Researchers at Cincinnati Children's Hospital Medical Center in collaboration with Roche, have developed a next-generation human liver organoid microarray platform that could help predict which drugs may cause harmful immune ...
Oct 14, 2025
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mRNA directs body to produce nanobodies that unlock immune attack on colorectal cancer tumors
A tiny molecule called a nanobody may succeed where today's cancer drugs often fail, according to University of Hawaiʻi at Mānoa researcher Stefan Moisyadi, who has been refining the concept for nearly a decade.
Oct 14, 2025
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Bioengineering breathes new life into failed cancer treatment
Many advanced cancers develop resistance to treatment and become highly aggressive, often leaving patients with limited treatment options. In some cancers, including lung, pancreatic and prostate tumors, a key driver of treatment ...
Oct 13, 2025
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Preclinical study identifies genetic misfire in lupus
Cedars-Sinai investigators have identified a "molecular switch" on a gene strongly associated with the autoimmune disease lupus, which appears to propel immune cells into overdrive, attacking and damaging healthy tissues ...
Oct 13, 2025
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How pollution and the microbiome interact with Tregs, the immune system regulators whose discovery won the Nobel Prize
A special group of immune cells known as regulatory T cells, or Tregs for short, became an overnight sensation when a trio of U.S. and Japanese scientists won the Nobel Prize in physiology or medicine on Oct. 6, 2025, for ...
Oct 13, 2025
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Blood cancer: Scientists reprogram cancer cell death to trigger immune system
The aim of immunotherapy strategies is to leverage cells in the patient's own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm successfully stimulated an effective ...
Oct 10, 2025
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Engineered stem cells yield millions of tumor-fighting natural killer cells at reduced cost
Chinese researchers have developed a novel method to efficiently engineer natural killer (NK) cells for cancer immunotherapy. NK cells are central to early antiviral and anticancer defense—among other immune system roles—making ...
Oct 10, 2025
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Targeted steroid use may offer a universal complementary treatment to fight TB
Tuberculosis (TB) remains a major global health challenge, affecting more than 10 million people annually worldwide, with 1.25 million people dying of TB every year. While steroids like dexamethasone are used in certain TB ...
Oct 10, 2025
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Liquid biopsy offers early detection of ICI-related myocarditis with 40% mortality rate
Treatments for cancer are continuously improving, but they can still cause debilitating, even fatal, side effects. Immune checkpoint inhibitors, or ICIs, have revolutionized cancer therapy, yet their use can trigger a rare ...
Oct 10, 2025
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Certain dietary fatty acids can supercharge cancer-fighting immune cells
A research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has discovered that certain dietary fatty acids can supercharge the human immune system's ability to fight cancer. The team found that ...
Oct 9, 2025
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Hormone replacement therapy may help restore immunity in menopausal women
A study led by researchers at Queen Mary University of London has found that hormone replacement therapy (HRT) may help reverse changes in the immune system caused by menopause, potentially boosting immune health. The research ...
Oct 9, 2025
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AI tool offers deep insight into the immune system
Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved. But there is a broad range of these, and observations necessarily produce vast amounts of data.
Oct 9, 2025
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Physical exercise can 'train' the immune system
In addition to strengthening the muscles, lungs, and heart, regular physical exercise also strengthens the immune system. This finding comes from a study of older adults with a history of endurance training, which involves ...
Oct 8, 2025
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Novel immunotherapy combination destroys colorectal liver metastases
Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver. Despite progress ...
Oct 8, 2025
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Repurposing an arthritis drug could significantly improve recovery from heart attack
Australian researchers have discovered that an anti-inflammatory drug already being used to treat rheumatoid arthritis could dramatically improve recovery from heart attacks. The work is published in the journal Cardiovascular ...
Oct 8, 2025
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Repeated brain tumor sampling uncovers treatment response in patients with glioblastoma
A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect ...
Oct 8, 2025
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Breastfeeding for at least six months strengthens immunity in babies, study suggests
Breastfeeding until at least six months helps babies to fight off infections and reduces chronic inflammation, according to a new study. And better understanding the way specific nutrients in breast milk impact the immune ...
Oct 8, 2025
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Research team including Nobel Prize laureate reveals regulatory immune cell precursors disrupted in severe COVID-19
A research team at The University of Osaka, joined by Professor Shimon Sakaguchi—the latest Nobel Laureate in Physiology or Medicine—has identified a previously uncharacterized subset of immune cells called precursor ...
Oct 8, 2025
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