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Immunology news
Cardiology
Researchers identify immunosuppressive pathway that helps newborn hearts regenerate in mouse models
When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. ...
18 hours ago
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Oncology & Cancer
The importance of the rhythmicity of the immune system for tumor growth
By examining the immune modulations of tumors during the day, scientists from the University of Geneva and the LMU Munich are demonstrating their impact on the diagnosis and management of patients.
19 hours ago
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Review explores cell-based immunotherapies for sepsis
Imagine the human body mounting an excessively heightened reaction to an infection, causing multiple organ failures and posing a risk of death. This condition, recognized as sepsis, affects approximately 49 million individuals ...
13 hours ago
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Biomarker could improve prediction of response to immunotherapy in melanoma
If melanoma spreads, there are various therapies that can be used. However, there is still insufficient research into who responds to which therapy and whether resistance may develop over time.
14 hours ago
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Study reveals immunotherapy's potential in boosting immune systems of older individuals
Published in Nature Aging, University of Minnesota Medical School researchers have provided new insight into enhancing immune responses in older individuals and the potential for using immunotherapy to make older adults less ...
May 15, 2024
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Pre- and post-surgical immunotherapy improves outcomes for patients with operable lung cancer, Phase III study finds
Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy—given before and after surgery—significantly improved event-free survival (EFS) in patients with resectable early-stage non-small ...
May 15, 2024
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This time, it's personal: Enhancing patient response to cancer immunotherapy
Immunotherapy has revolutionized the way we treat cancer in recent years. Instead of targeting the tumor itself, immunotherapies work by directing patients' immune systems to attack their tumors more effectively. This has ...
May 15, 2024
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New study identifies mechanism of immune evasion of SARS-CoV-2 and variants
A new study has revealed important insights into how SARS-CoV-2 and its variants escape the immune system. The findings pave the way for new therapeutic approaches against COVID-19.
May 15, 2024
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Breaking bad blood: How rogue neutrophils help lung cancer spread
Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide. Central to its development is the tumor microenvironment, which involves a complex interplay with ...
May 15, 2024
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Researchers explore the role of of transposable elements in myocarditis
Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation.
May 15, 2024
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Iron fuels immune cells—and it could make asthma worse
You've likely heard that you can get iron from eating spinach and steak. You might also know that it's an essential trace element that is a major component of hemoglobin, a protein in red blood cells that carries oxygen from ...
May 15, 2024
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Research finds exercise has a significant impact on immune cells that support brain function
New research published in Aging Cell provides insights into how exercise may help to prevent or slow cognitive decline during aging.
May 15, 2024
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Newly identified PET biomarker predicts success of immune checkpoint blockade therapy
The protein galectin-1 (Gal-1) has been identified as a new PET imaging biomarker for immune checkpoint blockade (ICB) therapy, allowing physicians to predict the tumor responses before beginning treatment.
May 14, 2024
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New study shows certain combinations of antiviral proteins are responsible for lupus symptoms
In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which affects up to 1.5 million ...
May 13, 2024
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Variations in 'ancient' immune cells linked to patients' survival in cancer
Researchers from the Cancer Science Institute of Singapore (CSI) at the National University of Singapore (NUS), have achieved breakthroughs in understanding relapse after chemotherapy for a type of cancer known as diffuse ...
May 13, 2024
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Study highlights need for cell-type-specific therapies in treatment of HIV
Researchers from the University of Illinois have demonstrated the importance of cell-type-specific targeting in the treatment of HIV. Their study, published in the Proceedings of the National Academy of Sciences, is one of ...
May 13, 2024
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Researchers use dual drug strategy to advance melanoma treatment against resistance
Research conducted by the Centenary Institute has revealed a promising new approach to tackling melanoma, an aggressive form of skin cancer notorious for its resistance to conventional treatments.
May 13, 2024
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Breakthrough therapies are saving lives, but can we afford them?
Harnessing the body's own cells to fight disease, long a medical dream, is finally a reality.
May 13, 2024
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Is 'herd immunity' in intensive care doing more harm than good?
Infections acquired by patients in intensive care units (ICUs) are bad news. These patients, many on life support, are already vulnerable. An infection will increase their chance of dying.
May 13, 2024
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Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy
In an editorial, in Oncoscience titled "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy," researcher Ioannis A. Voutsadakis from Sault Area Hospital and Northern Ontario School of Medicine ...
May 13, 2024
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