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Immunology news
Oncology & Cancer
Researchers discover how immune B cells hunt down cancer around the body
Scientists have discovered the key features of immune B cells that make them successful at targeting tumors—including when cancer has spread to a different part of the body.
16 hours ago
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Immunology
Controlled human infection study paves the way to improving vaccines and therapeutics development
A first-of-its-kind study led by the University of Oxford has successfully investigated human immunity against COVID-19 in people who already have antibodies against it. The results suggest that previous infection, together ...
20 hours ago
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Gene signatures from tissue-resident T cells as a predictive tool for melanoma patients
An extensive analytical study conducted at the Terasaki Institute for Biomedical Innovation (TIBI) has revealed an association between favorable survival outcomes for melanoma patients and the presence of higher populations ...
19 hours ago
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Activation of innate immunity: Important piece of the puzzle identified
LMU researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.
19 hours ago
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Turning a tumor's 'shield' into a weapon against itself
Tumor cells are "cunning," according to Peter Yingxiao Wang. They have a nefarious way of evading the human immune responses that fight back against these cancerous invaders. Tumor cells express programmed death-ligand 1 ...
21 hours ago
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Skin patch improves treatment for pediatric milk allergies
Daily immunotherapy delivered via a dermal patch reduced the risk of reactions, including anaphylaxis, in children with an immunoglobulin E (IgE)–mediated cow's milk allergy, according to a recent clinical trial published ...
21 hours ago
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Molecular testing: Pioneering precision medicine for colorectal cancer
A new perspective paper explores the current state and future directions of precision medicine in colorectal cancer (CRC). It outlines advancements in molecular testing and their implications for targeted and immunological ...
13 hours ago
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Study reveals hidden diversity of innate immune cells
Findings from a new study, led by researchers at Dartmouth's Geisel School of Medicine and published in Nature Immunology, have uncovered key functional differences in macrophages—a type of white blood cell that plays a ...
May 2, 2024
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New mRNA cancer vaccine triggers fierce immune response to fight malignant brain tumor
In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain ...
May 1, 2024
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New technique improves T cell-based immunotherapies for solid tumors
Scientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding solid tumors—such as in melanoma, breast, and prostate cancer—so T cells can more effectively kill tumor ...
May 1, 2024
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Experimental vaccine targets portions of the flu virus that don't change
Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.
May 1, 2024
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Scientists identify new brain circuit in mice that controls body's inflammatory reactions
The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.
May 1, 2024
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Researchers find difference in pancreatic cancer cells, offering new hope for immunotherapy effectiveness
A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors that could lead to better targeted treatments.
May 1, 2024
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Patients with rheumatoid arthritis have unique and complex autoantibody patterns, study reveals
Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease. Researchers at Utrecht University unveiled the complexity of these antibodies using ...
May 1, 2024
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For parents of kids with food allergies, social media can bring support—and stress
Having a child with food allergies isn't easy to manage, and now new research shows that most of these parents turn to social media for medical advice.
May 1, 2024
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Gene expression analyses identify potential drivers of chronic allergic inflammation
Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, ...
Apr 30, 2024
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Study finds some people have a uniquely human gene that enhances immune function
University at Buffalo researchers have found that the active form of a gene promotes a broad range of protective traits. The gene is found in 75% of the population and is known to protect against neurodegeneration. Now, UB ...
Apr 30, 2024
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Study highlights importance of early interventions to combat HIV
A study has compared the development of HIV reservoirs—locations in the body where the virus persists in a latent state—between patients who receive either early or late medical interventions. The findings highlight the ...
Apr 30, 2024
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Study finds Bcl6 protein is an important transcription factor for formation of certain dendritic cells
While previous studies have investigated the function of the protein Bcl6 in dendritic cells—in some cases with varying results—a new study published in Nature Communications has sought to harmonize the sometimes contradictory ...
Apr 30, 2024
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Targeting protein interactions may boost antitumor immunity in breast cancer
A multi-institutional team of investigators has discovered that targeting a specific protein interaction within immunosuppressive breast cancer cells may increase antitumor immune responses in otherwise difficult to treat ...
Apr 30, 2024
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