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Immunology news
Psychology & Psychiatry
Short-term stress primes immune cells for action in animal models
Stress affects many systems in our body and biologists Marcel Schaaf and Erin Faught at Radboud University are figuring out how that works. Their recent study showed how stress changes behavior by using two different receptors. ...
19 minutes ago
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Farm-living families develop earlier immune maturation against food allergies, study finds
Children who grow up in farming communities have long been known to develop far fewer allergies than their urban peers. A new study from the University of Rochester Medical Center (URMC), offers one possible reason why: their ...
1 hour ago
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Preoperative radiation may improve antitumor immune response in most common form of breast cancer
Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led ...
3 hours ago
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AI identifies key mpox protein for new vaccine and antibody therapies
With the help of artificial intelligence, an international team of researchers has made the first major inroad to date toward a new and more effective way to fight the monkeypox virus (MPXV), which causes a painful and sometimes ...
21 hours ago
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Next-generation CAR T cells show stronger, safer response in animal models
Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively killing cancer cells, ...
21 hours ago
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Cell-free DNA could detect adverse events from immunotherapy
A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to treatment with immune checkpoint inhibitor drugs, investigators at the Johns Hopkins Kimmel Cancer ...
18 hours ago
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Off-the-shelf immunotherapy offers new hope for toughest myeloma
A new Mayo Clinic study published in the New England Journal of Medicine has uncovered that an off-the-shelf, dual-antibody therapy can generate deep and durable responses in extramedullary multiple myeloma—one of the most ...
18 hours ago
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Study unveils improved mRNA cancer vaccine targeting
No matter where cancer cells grow in the human body, they are a threat to our health and our lives. But instead of treating them with chemotherapy or radiation—which have undesirable side effects—what if we could train ...
19 hours ago
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How can we better protect a transplanted kidney? AI-based antibody analytics point the way
When we think of kidney transplantation, we usually focus on surgery, immunosuppressive drugs, and early post-operative tests. Much less attention is paid to what happens months or years later, when a silent damaging process ...
20 hours ago
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Specialized gut cells linked to celiac disease reveal new immune role
The human small intestine absorbs nutrients while protecting us from potentially harmful microbes. One of the cell types that plays a key role in this protection is the microfold cell (M cell). These cells detect bacteria ...
21 hours ago
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New cancer therapy brings remission for patients with deadly T-cell leukemia
A small group of patients with an otherwise incurable form of T‑cell leukemia have seen their cancer driven into remission by an innovative form of immune therapy.
18 hours ago
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Immune 'switch' identified as a potential target to curb chronic inflammation in cirrhosis
Chronic liver inflammation is one of the most serious complications associated with liver cirrhosis. Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified a molecular mechanism that acts as ...
19 hours ago
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Immune system's 'on-off' switch may hold answers for cancer and autoimmunity
A single signaling pathway controls whether immune cells attack or befriend cells they encounter while patrolling our bodies, researchers at Stanford Medicine have found. Manipulating this pathway could allow researchers ...
Dec 10, 2025
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How the immune system stalls weight loss
Researchers at the University of California San Diego School of Medicine have uncovered a surprising new function for immune cells: preventing excess weight loss.
Dec 10, 2025
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In pneumonia's tug-of-war, lung microbiome could tip the balance
Northwestern University scientists have potentially uncovered a previously unknown, hidden player in pneumonia. In a new study, scientists found the lungs' own microbial community, or microbiome, appears to influence how ...
Dec 10, 2025
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Pulmonary fibrosis traced to key signaling pathway
Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which healthy lung tissue is gradually replaced by scar tissue. While the early events that initiate this change are poorly understood, recent research suggests ...
Dec 10, 2025
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Real-time imaging captures what happens to cancer cells arriving in the brain
Metastasis occurs when cancer cells break away from the original tumor and travel through the bloodstream to form new tumors in other parts of the body. It is the leading cause of cancer-related death. Brain metastasis is ...
Dec 10, 2025
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Anxiety and insomnia may lower natural killer cell count, potentially repressing immune function
Natural killer (NK) cells are the bodyguards of our immune system. As a first line of defense, they destroy invading pathogens, foreign bodies, and infected cells in early stages, thereby preventing them from spreading. NK ...
Dec 10, 2025
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Adding tucatinib to first-line maintenance therapy delays disease progression in HER2-positive metastatic breast cancer
Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab (Herceptin) and pertuzumab (Perjeta) delayed disease progression in patients with HER2-positive metastatic breast cancer, potentially extending ...
Dec 10, 2025
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FDA approves expanded indication for Jaypirca
The U.S. Food and Drug Administration has approved an expanded indication for Eli Lilly's Jaypirca (pirtobrutinib), the first and only noncovalent Bruton tyrosine kinase (BTK) inhibitor for adults with relapsed or refractory ...
Dec 10, 2025
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Sacituzumab govitecan-hziy led to similar progression-free survival as standard of care for some breast cancers: Trial
Patients with hormone receptor (HR)-positive, HER2-negative advanced breast cancers had similar progression-free survival (PFS) whether they were treated with sacituzumab govitecan-hziy (Trodelvy) or standard-of-care chemotherapy ...
Dec 10, 2025
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Dietary restriction fuels T cells with ketones, boosting their cancer-fighting stamina
Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators. The findings lay the groundwork for developing dietary strategies ...
Dec 9, 2025
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Disarming cancer stem cells' shield makes immunotherapy more effective
Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, it works very well in shrinking tumors and sending cancer into remission, an undetectable state of ...
Dec 9, 2025
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Experimental antibody enables lasting platelet stability in autoimmune bleeding condition
More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune disorder that can cause life-threatening ...
Dec 9, 2025
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