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Allergy and immunology news
Study identifies new strategy to overcome immunotherapy resistance in colorectal cancer
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have identified a promising new strategy to overcome resistance to immunotherapy in colorectal cancer, one of the leading ...
12 hours ago
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Hidden sex differences may explain why lupus strikes women far more often
Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and UNSW Sydney helps explain why women are significantly more likely to be diagnosed with an autoimmune disease—a condition where ...
16 hours ago
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Scientists take crucial step in developing world's first measles treatment
Scientists at La Jolla Institute for Immunology (LJI) are the first in the world to characterize human antibodies capable of neutralizing measles virus. These antibodies bind to key sites on measles virus and prevent the ...
16 hours ago
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Turning up the volume on macrophage-driven immune responses
As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system. However, the ability of macrophages to interpret and respond to diverse danger signals remains ...
17 hours ago
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Chronic bowel disease involves multiple types of inflammation happening at once, study reveals
Chronic immune diseases are shaped by multiple inflammatory processes happening at the same time, each in different parts of the tissue. This finding from Karolinska Institutet, published in the journal Immunity, is based ...
18 hours ago
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Combination therapy with stem cell-derived immune cells boosts anti-cancer response
Cancer immunotherapy is built on a simple but powerful idea: the immune system can recognize and destroy cancer cells if it is properly activated. In many patients, however, this response is too weak or too slow to be effective. ...
11 hours ago
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Why zebrafish hearts heal so well: Early immune signals can improve repair even further
When the human heart is damaged by a heart attack, stiff scar tissue eventually forms around the affected areas. This weakens the heart's pumping ability and increases the risk of heart failure and arrhythmias. Zebrafish, ...
May 6, 2026
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Controlled peanut intake may reduce allergies in toddlers
Researchers at Karolinska Institutet have successfully treated children aged 1–3 years with peanut allergies. The children slowly became accustomed to eating peanuts by consuming small amounts of them daily, which were gradually ...
May 6, 2026
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How HIV hijacks a cellular 'gateway' to infect resting immune cells
Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells. The discovery challenges a decades-old assumption in HIV biology, and opens new ...
May 6, 2026
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Can AI forecast immune responses? New benchmark shows where predictions hold up and fail
Artificial intelligence is increasingly being used to help scientists accelerate drug discovery and search for new treatments. But for AI tools to work effectively, researchers need to know whether they can be validated and ...
May 6, 2026
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FDA approves Dupixent for chronic spontaneous urticaria in young children
The U.S. Food and Drug Administration has approved Sanofi and Regeneron's Dupixent (dupilumab) for the treatment of children (aged 2 to 11 years) with chronic spontaneous urticaria (CSU).
May 5, 2026
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Blocking stress signals could limit harmful inflammation after heart attack
After a heart attack, the body rapidly floods the injured heart with neutrophils—white blood cells that help repair damage but can also make it worse when too many arrive too quickly. New research from the University of Oklahoma ...
May 2, 2026
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Ticked off: How a bite can turn meat against you
Mammalian meat allergy (MMA) is one of the few known food allergies caused by an environmental trigger—a tick bite. In simple terms, MMA results in an allergic reaction to red meat, making it difficult or sometimes even impossible ...
May 1, 2026
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Why this CAR T advance matters: Complete remissions without chemotherapy at doses as low as 250,000 cells/kg
Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and mount potent anti-tumor responses. These properties make them an attractive candidate for next-generation ...
Apr 30, 2026
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For 30 years, doctors chased the wrong immune culprit behind this rare inflammatory disease
Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder. The study, published ...
Apr 30, 2026
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T cells secrete DNA to boost the immune system's cancer-fighting ability
Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell Medicine. The discovery ...
Apr 30, 2026
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Restoring protein recycling helps exhausted T cells fight tumors again
T cells are crucial components of our immune system, serving as critical protectors against infection and disease. But there are limits to their defensive capabilities. T cells are not inexhaustible protectors. Often, when ...
Apr 30, 2026
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Q&A: Why feeling sick may be important for surviving infection
Symptoms such as fatigue, loss of appetite, altered sleep, and social withdrawal are often treated as inconvenient side effects of infection. While some scientists have suggested that they may serve a protective function, ...
Apr 30, 2026
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Scientists recruit red blood cells to deliver genetic cargo with instructions to kill cancer
Scientists have developed a way to turn the body's own immune cells into cancer-fighting agents—without removing them from the body—by using red blood cells to deliver genetic instructions. Current CAR (chimeric antigen receptor) ...
How eating primes immune cells for future responses
Diets and healthy eating habits hold promise for preventing and treating diseases, but far less is known about acute effects on the immune system shortly after a meal.
Apr 29, 2026
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Your nose may be the gateway to a stronger immune system
At the moment, an influenza vaccine called FluMist is the only licensed intranasal vaccine approved for use in humans. The vaccine is administered through a spray of fluid in the nose, rather than with an injection.
Apr 29, 2026
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A natural molecule boosts CAR-T therapy and turns cold tumors hot
CAR-T cell therapy works well in blood cancers, but many patients still become resistant. A key reason is the presence of CAR-T regulatory T cells (CAR-Tregs), which weaken immune responses. Therefore, selectively targeting ...
Apr 29, 2026
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New dual-target drug may help overcome immunotherapy resistance in pancreatic cancer
Pancreatic ductal adenocarcinoma is one of the deadliest cancer types, with a five-year survival rate of 13%. There are only two treatment regimens available with limited efficacy. Pancreatic cancers do not respond to immunotherapy ...
Apr 29, 2026
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Why CAR T therapy works for some patients but fails for others may be getting clearer
Chimeric antigen receptor (CAR) T-cell therapy is one of oncology's most powerful ideas: Harvest a cancer patient's own immune cells, genetically engineer them to recognize tumor cells, multiply them in a laboratory and reinject ...
Apr 29, 2026
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Maternal antibodies in pregnancy may shape lifelong defenses against gum disease
A study from the Hebrew University of Jerusalem has identified a significant link between maternal care and lifelong oral health. Led by Prof. Avi-Hai Hovav and the DMD/Ph.D. student Reem Naamneh from the Faculty of Dental ...
Apr 29, 2026
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