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Allergy and immunology news
New research reveals underlying mechanisms of eye inflammation
A new study published in The American Journal of Pathology provides new evidence that immune cells enter the retina via the body's standard pathway, identifying PECAM as the gatekeeper and neutrophils as proresolving mediators. ...
12 hours ago
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Mechanism behind dangerous blood-clotting disorder uncovered
A cross-campus team of McMaster University researchers has identified why some patients develop dangerous blood clots after exposure to a common blood thinner—and a potential way to prevent them.
Sep 11, 2026
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Antiviral defense gained at the cost of autoimmunity risk, study shows
Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?
Sep 11, 2026
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Mitochondrial RNA escape may explain how chronic immune signaling helps tumors grow
Cancer biology—and, in turn, cancer treatment—have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy, a treatment strategy first deployed in 2011 that leverages ...
Sep 10, 2026
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Beyond B cells: Rituximab response may reveal which kidney disease patients can stop steroids
Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine. It is usually treated with steroids, but in some cases, steroids alone are insufficient, ...
Sep 10, 2026
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Can a tick bite create a meat allergy and increase heart disease risk?
Many people associate a bite from a tiny tick with a bacterial infection known as Lyme disease. But that bite can also trigger a potentially life-threatening meat allergy and may increase the risk of heart disease. Researchers ...
Sep 10, 2026
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Immunity for the long haul: Why some antibodies are built to last
When an infection strikes, the immune system produces antibodies to help fight it off. Some antibody responses can protect us for years, while others fade much sooner. Using a mouse model, a team of researchers led by The ...
Sep 9, 2026
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Bacterial trial fails to demonstrate early asthma prevention
A national clinical trial led by researchers at the University of Arizona College of Medicine—Tucson found that treating young children with an oral bacterial extract did not reduce the risk of severe wheezing and respiratory ...
Sep 9, 2026
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Preclinical antibody approach aims to treat type 1 diabetes at its immune source
Seven years ago, Johns Hopkins researchers and their collaborators announced they had found the X cell, a novel immune cell that plays a key role in the development of type 1 diabetes.
Sep 9, 2026
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Triple-negative breast cancer: Tumor metabolite aids cancer's escape from immune system
Cancer cell metabolism may play a key role in tumors' ability to evade the immune system. In a study published in the Journal for ImmunoTherapy of Cancer, researchers from GIGA demonstrate that methylglyoxal, a byproduct ...
Sep 9, 2026
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Early signs of eczema, food allergies may appear on infants' skin
The first clues that a baby may develop eczema or food allergies could be hiding in the microscopic organisms living on their skin, according to a study led by researchers in Washington State University's College of Veterinary ...
Sep 9, 2026
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Scientists engineer ready-to-use cancer-fighting T cells for solid tumors
T-cell receptor, or TCR, therapy is a cancer treatment that genetically reprograms immune cells, called T cells, to hunt down cancer with precision. It's similar to another treatment, CAR T-cell therapy, but with one key ...
Sep 8, 2026
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Specific CAR T-cell subgroup could make lower-dose cancer therapy more effective
Immunotherapies strengthen the body's own anticancer defenses in a highly targeted manner. In therapies using so-called CAR T cells (chimeric antigen receptor T cells), a patient's immune cells are genetically engineered ...
Sep 8, 2026
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Hidden immune cells may hold key to tackling female infertility
University of Manchester scientists have uncovered a hidden role for immune cells in the womb, opening the door to new treatments for infertility, miscarriage and other reproductive conditions that affect millions of women ...
Sep 8, 2026
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Vitamin A metabolite keeps immune cells active against recurrent brain tumors
Immune cells can become exhausted after prolonged exposure to cancer, gradually losing their ability to attack tumor cells. This phenomenon is particularly pronounced in aggressive brain tumors and can severely limit the ...
Sep 8, 2026
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Do I have asthma? All you need to know about symptoms, diagnosis and treatments
Asthma is a long-term condition, but there are ways to keep it under good control so that you feel your best.
Sep 8, 2026
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Australian pollen season may be arriving early in eastern states
The 2026 Australian pollen season has started, with some people in the eastern states reporting that their hay fever symptoms have begun earlier than normal. Compared with last year, satellite imaging suggests the eastern ...
Sep 8, 2026
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A single IV treatment retrains immune cells to fight autoimmune diseases in early trial
CAR T-cell therapy is an immune-reprogramming procedure that turns a patient's own immune cells into cancer-fighting specialists. The entire process is complex, but researchers have now found a faster way to achieve similar ...
MLC1 antibody identified as possible trigger of rare neurological autoimmune disorder
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system in which the immune system attacks structures in the brain, spinal cord and optic nerve. It mostly affects astrocytes, ...
Sep 7, 2026
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Atherosclerosis may meet key criteria for autoimmune disease, evidence suggests
In autoimmune diseases, the immune system turns against the body through pathogenic high-affinity B cells or T cells, leading to severe organ damage. Multiple sclerosis (nervous system paralysis), type 1 diabetes (a strong ...
Sep 7, 2026
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Study identifies key driver of inflammation, opening door to potential new treatments
Researchers at Johns Hopkins Medicine have uncovered a critical biological mechanism that helps explain how inflammation is triggered and sustained in a wide range of diseases—highlighting a promising avenue for future therapeutic ...
Sep 5, 2026
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Cerebroid study hints at how maternal inflammation may influence fetal brain development
Past studies suggest that a mother-to-be's heightened immune responses during pregnancy are linked to a higher risk of conditions affecting their offspring's brain development. While this association is well documented, the ...
Rethinking radiotherapy may boost immunotherapy for pancreatic cancer
Pancreatic cancer remains one of the most aggressive malignancies, with a particularly poor prognosis even when diagnosed at a localized stage. In a paper published in Nature Reviews Gastroenterology & Hepatology, researchers ...
Sep 4, 2026
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Sibling data reveal genetic clusters across 22 autoimmune diseases
Autoimmune diseases arise when the immune system mistakenly attacks the body's own tissues. Researchers have long known that these diseases tend to run in families, but the genetic relationships between different autoimmune ...
Sep 4, 2026
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