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Allergy and immunology news
CAR T cells with boosted BACH2 protein can fight cancer more effectively
UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving their therapeutic effectiveness. ...
Jan 23, 2026
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A balancing act: Dual mRNA markers in T cells act as a kill switch to prevent an overactive immune system
How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill switch holds potential for controlling infections or preventing ...
Jan 22, 2026
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Discovery illuminates how inflammatory bowel disease promotes colorectal cancer
A chain of immune reactions in the gut—driven by a key signaling protein and a surge of white blood cells from the bone marrow—may help explain why people with inflammatory bowel disease (IBD) have a higher risk of colorectal ...
Jan 22, 2026
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Experimental CAR T therapy targets tumor's immune shield, not cancer cells directly
Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the ...
Jan 22, 2026
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Redefining the role of neutrophils to open new avenues for cancer and inflammation therapies
Researchers from Universidad Carlos III de Madrid (UC3M), the National Center for Cardiovascular Research (CNIC), and Yale University (U.S.) have published a comprehensive review article in the journal Cell that proposes ...
Jan 22, 2026
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Cancer vaccines promise personalized, combination treatment approaches, says research
A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, ...
Jan 22, 2026
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Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment involves CD8⁺ T cells, also known as killer T cells, which play a crucial role in attacking tumors. ...
Jan 21, 2026
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Is it cedar fever or the flu? How Texans can tell the difference
Texas winters herald the bane of many allergy sufferers: cedar fever.
Jan 21, 2026
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Body's internal clock shapes stroke severity and treatment response, finds study
A study led by scientists at the Centro Nacional de Investigaciones Carlos III (CNIC) demonstrates that stroke severity depends on the time of day the event occurs. The research shows that neutrophils—the most abundant ...
Jan 21, 2026
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Specialty care remains out of reach for many children with uncontrolled asthma
Historically, marginalized children would benefit from better connection to specialists
Jan 21, 2026
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B cells play a more sinister role than believed in progression of type 1 diabetes
A recent study by Vanderbilt Health researchers has revealed a greater, detrimental role for B lymphocytes (B cells) in the progression of type 1 diabetes (T1D).
Jan 20, 2026
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Dual gene deletion reveals potential biomarkers for predicting immunotherapy success
The deletion of two cancer genes, CHD1 and MAP3K7, improves how well tumors respond to cancer immunotherapy and could be used as biomarkers to help predict which patients are most likely to benefit from treatment, new research ...
Jan 20, 2026
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Certain antibiotics may may boost immune system
Research led by Lancaster University has discovered that a class of antibiotics—fluoroquinolones—can directly alter the potential bacterial killing ability of one of our immune cells called the macrophage.
Jan 20, 2026
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Study links stroke-induced stress response to weakened immune system and higher infection risk
A new University of Manchester and Edinburgh study published in the journal Brain, Behavior and Immunity has found that people who have had a stroke have fewer of a specific type of immune cell called B cells, which normally ...
Jan 20, 2026
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Pan-fungal vaccine proves effective against Candida auris in mice
A vaccine created by University of Georgia researchers to battle multiple life-threatening fungal infections is also effective against Candida auris in mice, according to a new study published in Vaccines by researchers in ...
Jan 20, 2026
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Can training your brain boost immune response? Vaccination study highlights power of positive thinking
Training people to activate a part of the brain linked to reward and positive expectations may be associated with an increase in the body's immune response to a vaccine. The findings from a study involving 85 participants, ...
Jan 19, 2026
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Small molecules could treat Crohn's disease by mimicking a protective gene variant
An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis. But a lucky few individuals are far less likely to develop IBD because they have a rare variant of a ...
Jan 19, 2026
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New method predicts asthma attacks up to five years in advance
Researchers at Mass General Brigham and Karolinska Institutet have identified a new method to predict asthma exacerbations with a high degree of accuracy. The study is published in Nature Communications.
Jan 19, 2026
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Federal officials scale back childhood vaccination schedule in historic move
A decision by federal officials to scale back the number of vaccines recommended for children surprised some Northeastern University public health experts, who warn the move could confuse parents and increase the risk of ...
Jan 19, 2026
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A 'recipe book' for reprogramming cells into disease-fighting immune cells
In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created a library of the 400 ...
Jan 18, 2026
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Tumor cells steal immune mitochondria to aid lymph node spread
Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune function and activating cGAS-STING and type I interferon signaling that promotes lymph node metastasis.
Scientists discover natural 'brake' that could stop harmful inflammation
Researchers at University College London (UCL) have uncovered a key mechanism that helps the body switch off inflammation—a breakthrough that could lead to new treatments for chronic diseases affecting millions worldwide.
Jan 16, 2026
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Molecular 'switch' that turns on inflammation in obesity points to new therapeutic targets
A team led by UT Southwestern Medical Center researchers has uncovered a molecular pathway that links obesity to widespread inflammation, providing long-sought insight into why obesity increases the risk of type 2 diabetes, ...
Jan 16, 2026
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Reversing immune suppression in pancreatic cancer could lead to novel therapies
In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells ...
Jan 16, 2026
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Asthma-related depression may be biologically distinct from primary depression
Researchers from Hiroshima University in Japan and collaborating institutions have found that adults with asthma who experience symptoms of depression have elevated blood levels of a protein called brain-derived neurotrophic ...
Jan 16, 2026
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