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Immunology news

Immunology

High-dose risankizumab trial tests staying power against psoriasis

Oregon Medical Research Center in Portland, Oregon, has led a phase 2 trial in moderate-to-severe plaque psoriasis that paired higher-than-approved doses of risankizumab with extended follow-up and found high early skin clearance ...

Oncology & Cancer

Combination therapy for Burkitt's lymphoma dramatically improves cure rates in mice

Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most often in children and young adults. In recent years, CAR-T cell therapy—often referred to as a "living ...

Diseases, Conditions, Syndromes

New lab-made antibody matches IVIG effectiveness at lower doses in mice

Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions. With origins dating back to the 1950s, IVIG is currently FDA-approved for four diseases ...

Immunology

AI can speed antibody design to thwart novel viruses

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional ...

Immunology

Q&A: How to spark immune hotspots that attack tumors

Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary lymphoid-like structures (TLSs). These immune cell clusters are increasingly linked to improved outcomes ...

Immunology

Thunderstorms linked to surge in asthma ER visits

A new study finds that thunderstorms can trigger sharp increases in asthma-related emergency department (ED) visits, underscoring the importance of storm preparedness for people with asthma. The research is being presented ...

Oncology & Cancer

Why cancer immunotherapy isn't effective for everyone

A study led by André Veillette, a researcher at the Montreal Clinical Research Institute (IRCM) and a professor in the Faculty of Medicine at University of Montreal, sheds new light on the complexity of the immune system ...