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Immunology news

Immunology

High-dose risankizumab trial tests staying power against psoriasis

Oregon Medical Research Center in Portland, Oregon, has led a phase 2 trial in moderate-to-severe plaque psoriasis that paired higher-than-approved doses of risankizumab with extended follow-up and found high early skin clearance ...

Neuroscience

Potential biomarker linked to multiple sclerosis progression and brain inflammation

A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.

Immunology

Key lung immune cells can intensify allergic reactions

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...

Immunology

RSV vaccines could offer protection against asthma

Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases ...

Arthritis & Rheumatism

Why certain arthritis drugs don't work in rheumatoid arthritis

Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...

Immunology

How a mitochondrial mutation rewires immune function

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single ...

Immunology

Certain immune cell subtypes drive lupus, study finds

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine ...