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Inflammatory disorders news

Immunology

Steroid inhalers / pills for asthma linked to heightened risk of brittle bones and fractures

Taking steroid inhalers or tablets to treat asthma or control flare-ups is linked to a heightened risk of brittle bones (osteoporosis) and increased vulnerability to broken bones (fragility fractures), finds research published ...

Neuroscience

The choroid plexus: A conduit for prenatal inflammation?

Floating in fluid deep in the brain are small, little understood fronds of tissue. Two new studies reveal that these miniature organs are a hotbed of immune system activity. This activity may protect the developing brain ...

Diseases, Conditions, Syndromes

Computer model shows how COVID-19 could lead to runaway inflammation

A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular structure ...

Medical research

Cell therapy designed to treat inflammatory bowel disease

The UPV/EHU's NanoBioCel research group is developing systems that enable cells to be used as drugs. Cell therapy raises hopes for treating those diseases for which there are as yet no effective pharmacological solutions. ...

Cardiology

Impact of psoriasis explored for hospital outcomes of acute MI

(HealthDay)—Myocardial infarction (MI) events may occur earlier in life in patients with psoriasis, which in turn may affect hospital outcomes, according to a study published online Sept. 11 in the Journal of the American ...

Inflammatory disorders

Antibiotic pre-treatment reduces joint inflammation

Tearing an anterior cruciate ligament (ACL) can be an excruciatingly painful injury. Nearly 50 percent of these patients will develop a secondary form of osteoarthritis, deemed post-traumatic osteoarthritis (PTOA).

Medications

Adding belimumab improves renal outcome in lupus nephritis

(HealthDay)—The addition of belimumab versus placebo to standard therapy increases the likelihood of a primary efficacy renal response in patients with active lupus nephritis, according to a study published in the Sept. ...

Inflammatory disorders

New imaging agent spotlights inflammation

Many of the most common diseases—cancer, diabetes, cardiovascular and lung disease, and even COVID-19—have been linked to chronic or excessive inflammation. Blood tests can indicate that some part of a person's body is ...

Medications

Common diabetes drug reverses inflammation in the liver

The diabetes drug metformin—derived from a lilac plant that's been used medicinally for more than a thousand years—has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 ...

Inflammatory disorders

Shift seen to newer agents to treat psoriasis

(HealthDay)—Phototherapy use for psoriasis decreased from 2005 to 2018, while use of biologics increased, according to a research letter published online Sept. 4 in Dermatologic Therapy.

Alzheimer's disease & dementia

Study links inflammation to Alzheimer's disease development

Alzheimer's disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease ...