A better COVID treatment for the immunocompromised? Researchers create a non-toxic potential alternative to Paxlovid
A combination of two antiviral compounds may be a promising alternative to Paxlovid when treating COVID-19 in immunocompromised patients, according to Karen S. Anderson, Ph.D., professor of pharmacology and of molecular biophysics ...
Apr 30, 2024
0
52
Withdrawal of stop-smoking pill could lead to thousands of avoidable deaths
The disruption to the supply of a prescription medicine that helps people stop smoking may have led to thousands fewer people quitting each year in England, which will lead to avoidable deaths in future, suggests a new study ...
Apr 30, 2024
0
1
Study assesses health care providers' knowledge, attitudes, perception regarding Halal pharmaceuticals
The way religious beliefs and medical treatments intersect can really affect how people use medications and stick to their treatment plans. Lately, there's been talk about "Halal pharmaceuticals," which are drugs made to ...
Apr 30, 2024
0
0
Oral fungal infection treatment shows promise in preclinical trials
A novel oral amphotericin B (MAT2203) developed by Matinas BioPharma for treatment of invasive mucormycosis (IM) and other deadly invasive fungal infections, has demonstrated encouraging results in a series of preclinical ...
Apr 30, 2024
0
0
Protective effects of cyclosporine and NIM-811 in murine hepatic ischemia-reperfusion injury
During hepatic surgery or liver transplantation, the liver is vulnerable to ischemia-reperfusion injury (IRI), especially when vessels are compressed to control bleeding or during periods of ischemia. The hallmark of IRI ...
Apr 30, 2024
0
0
California strikes deal for cheaper overdose-reversing medication
California struck up a new deal with Amneal Pharmaceuticals on April 29 to bolster the state's supply of the opioid overdose-reversing medication naloxone at a much lower price for schools, police departments and others trying ...
Apr 30, 2024
0
0
Experimental drug shields pancreas from type 1 diabetes attack
Scientists at Johns Hopkins Medicine say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' ...
Apr 29, 2024
0
11
Cabozantinib promising for advanced adrenocortical carcinoma
For patients with advanced adrenocortical carcinoma, cabozantinib shows promising efficacy, according to a study published online April 9 in The Lancet Oncology.
Apr 29, 2024
0
1
Curbing the price of novel diabetes and obesity medications
For years, Kasia Lipska, MD, MHS, associate professor of medicine (endocrinology) at Yale School of Medicine (YSM), has been advocating for affordable pricing of insulin, an essential —and sometimes lifesaving—drug for ...
Apr 29, 2024
0
0
The aspirin conundrum: Navigating negative results, age, aging dynamics and equity
A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers ...
Apr 29, 2024
0
1
Clinical trial evaluates azithromycin for preventing chronic lung disease in premature babies
The early use of azithromycin does not prevent the development of chronic lung disease in premature babies, finds new research by Cardiff University.
Apr 26, 2024
0
47
Patients prescribed gabapentinoids at increased risk of drug misuse or overdose, researchers find
Doctors and clinicians must exercise extreme caution when selecting patients to prescribe gabapentinoids to, Keele researchers have said, after finding a link between gabapentinoid prescriptions and a higher risk of worse ...
Apr 26, 2024
0
0
'Drug take back day' is Saturday: Check for leftover opioids in your home
Each year, thousands of Americans head home after a surgery clutching prescription opioids to help ease post-surgical pain.
Apr 26, 2024
0
0
Targeting specific protein regions offers a new treatment approach in medulloblastoma
Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group 3 medulloblastoma ...
Apr 25, 2024
0
11
Treatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research from the University of Houston ...
Apr 25, 2024
0
2
National trial safely scales back prescribing of a powerful antipsychotic for the elderly
Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health. Researchers used Medicare data to study the ...
Apr 25, 2024
0
0
Diabetes drug shows promise for the treatment of acute heart failure
A multicenter study led by Vanderbilt University Medical Center (VUMC) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure, a leading cause of hospitalization ...
Apr 25, 2024
0
35
Study: Antibiotic use in patients hospitalized with COVID-19 appears to have no beneficial effect on clinical outcomes
Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ...
Apr 25, 2024
0
16