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Medications
Sluggish uptake of new antibiotics threatens future development and supply for highly resistant infections
A large retrospective cohort pharmacoepidemiologic study found that despite approval by the U.S. Food and Drug Administration (FDA) for seven new gram-negative antibiotics between 2014 and 2019, clinicians in U.S. hospitals ...
22 hours ago
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UK, EU face significant medicine shortages: Study
Patients in the UK and European Union are facing shortages of vital medicines such as antibiotics and epilepsy medication, research published Thursday found.
Apr 18, 2024
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Which treatments for malnutrition's long-term effects could help reduce mortality and health outcomes for children
A comparison of treatments for malnutrition enteropathy, caused by severe acute malnutrition (SAM), has found evidence supporting the use of treatments to enhance the healing of mucosal membranes and reduce inflammation in ...
Apr 17, 2024
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Ketamine produces wide variety of responses in the brain, researchers find
Since Yale researchers first observed the ability of the anesthetic ketamine to dramatically improve symptoms in many patients with treatment-resistant depression more than two decades ago, the drug has provided a powerful ...
Apr 17, 2024
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Antipsychotics for dementia linked to more harms than previously acknowledged
Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, ...
Apr 17, 2024
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Erenumab effective, safe for rosacea-linked erythema, flushing
The anticalcitonin gene-related peptide-receptor monoclonal antibody erenumab is effective and safe for treatment of rosacea-associated erythema and flushing, according to a study published in JAMA Dermatology.
Apr 17, 2024
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Are probiotics all they're cracked up to be?
Probiotics have been touted as a treatment for everything from diarrhea to mental health disorders, with sales of probiotic supplements expected to exceed $65 billion globally in 2024.
Apr 17, 2024
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New drug may slow rapid progression of Parkinson's disease
Prasinezumab, a monoclonal antibody, is shown to reduce signs of motor deterioration in individuals with Parkinson's disease (PD) who have rapidly progressing disease, as reported in an exploratory analysis of data from a ...
Apr 16, 2024
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Common HIV treatments may aid Alzheimer's disease patients
Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need. Scientists ...
Apr 16, 2024
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Combination therapy can delay resistance of lung cancer cells
A specific genetic alteration, known as an ALK fusion, drives non-small cell lung cancer in some patients. This abnormality leads to excessive activity of the ALK protein, a key cancer promoter. These tumors can be treated ...
Apr 16, 2024
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Scientists identify targets to protect against anthracycline-induced cardiotoxicity
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified the mechanisms through which anthracyclines, a widely used class of anticancer drugs, damage the hearts of patients receiving this ...
Apr 16, 2024
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Melatonin gummies to get safety labeling, child-safe bottles after poisonings
In the wake of a sharp rise in the number of young children accidentally eating melatonin supplements, an industry group has called for tougher safety guidelines for packaging and labeling the sleep-aid supplements.
Apr 16, 2024
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Large study finds antibiotics aren't effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment in U.S. primary or urgent care ...
Apr 15, 2024
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Epilepsy drug prevents brain tumors in mice with neurofibromatosis type 1
A drug used to treat children with epilepsy prevents brain tumor formation and growth in two mouse models of neurofibromatosis type 1 (NF1), according to a study by researchers at Washington University School of Medicine ...
Apr 15, 2024
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Researchers say common dementia medication doesn't increase risk of death, life-threatening heart abnormalities
Researchers with McMaster University have found that a commonly prescribed dementia medication doesn't increase the risk of death or certain heart rhythm problems, contrary to past warnings.
Apr 15, 2024
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Study finds inverse association between weight loss drugs and multiple sclerosis
Initially, diabetes drugs like Ozempic and Wegovy showed promise in weight loss and have subsequently been marketed and widely used for weight loss. Now these medications are showing promise as a possible treatment for multiple ...
Apr 15, 2024
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Psychedelics could make mental health worse in people with a personality disorder
The interest in psychedelics is growing both in scientific circles and among the public. These are powerful substances capable of altering perception, mood and various mental processes. They also show promise for treating ...
Apr 15, 2024
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Penicillin allergy can be delabeled by nonallergy providers
Direct oral penicillin challenges (DPCs) can be delivered to patients with penicillin allergy labels (PALs) by nonallergy health care professionals (HCPs), according to a study published in the March issue of the Journal ...
Apr 14, 2024
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ACC: Ticagrelor monotherapy cuts bleeding risk in acute coronary syndrome
Treatment with ticagrelor alone results in a lower rate of clinically relevant bleeding compared with ticagrelor and aspirin among patients with an acute coronary syndrome who had percutaneous coronary intervention and remained ...
Apr 13, 2024
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