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Weight management news
Oral small-molecule GLP-1 drugs penetrate deep into the brain to suppress cravings
A study has found that an emerging class of GLP-1 weight-loss drugs suppresses eating for pleasure, or hedonic feeding, in mice by modulating a reward circuit deep within the brain. This newly charted pathway—separate from ...
18 hours ago
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Abdominal obesity may lead to more severe menopause symptoms
Weight gain during menopause is common, with abdominal obesity being especially common and unhealthy. A new study based on data from the Study of Women's Health Across the Nation (SWAN) has found that in addition to its adverse ...
16 hours ago
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Bariatric surgery significantly more effective than GLP-1 drugs for weight loss and disease remission, review finds
Metabolic and bariatric surgery delivers significantly greater weight loss and higher rates of obesity-related disease remission than glucagon-like peptide-1 receptor agonists (GLP-1s), according to one of the largest and ...
23 hours ago
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Bariatric surgery more effective than GLP-1 drugs at preventing heart attacks, stroke and death in older adults
Metabolic and bariatric surgery offers significantly greater long-term protection against heart attack, stroke and death than widely used GLP-1 drugs in older adults with obesity and diabetes, according to a new real-world ...
23 hours ago
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Obesity and Alzheimer's linked by disease-driving metabolic pathways
By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the burden of age-related diseases, particularly Alzheimer's disease ...
May 5, 2026
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The critical role of exercise in the GLP-1 era
As GLP-1 receptor agonists reshape obesity treatment, a new medical perspective published in JAMA, underscores a persistent gap in care: integrating exercise into weight management in ways patients can sustain.
May 5, 2026
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Study finds bariatric surgery less costly than GLP-1 drugs over time
A new real-world analysis of more than 90,000 patients with obesity and type 2 diabetes finds metabolic and bariatric surgery costs significantly less than weekly injections of GLP-1 drugs over a two-year period, according ...
May 5, 2026
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Gut hormone FGF15 changes how mice respond to weight loss
Nearly 40% of the population in the United States develop obesity, which is linked to the development of several diseases, including type 2 diabetes and metabolic liver disease. The rise in obesity is, in part, caused by ...
May 5, 2026
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Hidden muscle fat poses danger to heart and metabolism, deep learning model reveals
Using a deep learning model to analyze the composition of large muscles on MRI, German researchers found that the proportions of intermuscular fat and lean muscle mass were associated with high blood pressure and unhealthy ...
May 5, 2026
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Most severe obesity still goes untreated as GLP-1 use climbs and surgery slips
Drawing on electronic health records from nearly 20 million patients with severe obesity, researchers from University of California San Diego find that GLP-1 prescriptions have grown exponentially—from less than 4,600 prescriptions ...
May 5, 2026
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Bariatric surgery slashes risk of kidney failure, heart attack and death, new data show
Metabolic and bariatric surgery, also known as weight-loss surgery, dramatically improves outcomes for patients with obesity and chronic kidney disease (CKD), significantly reducing the risk of kidney failure, major cardiovascular ...
May 5, 2026
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Metabolic and bariatric surgery after GLP-1 treatment significantly boosts weight loss, research finds
People who begin obesity treatment with glucagon-like peptide-1 receptor agonists (GLP-1s) and then undergo metabolic and bariatric surgery achieve substantially greater weight loss than with the medications alone, according ...
May 5, 2026
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Bariatric surgery procedures fall below 200,000, first time since 2020, new research finds
The number of metabolic and bariatric surgery procedures in the United States dropped below 200,000 in 2024 for the first time since 2020, a more than 20% decline from the prior year, according to new research presented at ...
May 5, 2026
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The GLP-1 paradox: Weight loss drugs may lead to stigma
Glucagonlike peptide-1 (GLP-1) medications have taken over the national conversation around weight loss. From celebrity headlines to everyday conversations, GLP-1 drugs like Ozempic and Wegovy are often framed as breakthroughs ...
May 4, 2026
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Managing weight may slow brain aging within two years, 24-year data suggest
Being overweight may lead to accelerated cognitive decline, according to new research from the University of Georgia. The paper is published in the Journal of Neurology.
May 4, 2026
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Stopping and restarting certain GLP-1s to lose weight may make the drug less effective
Inconsistent use of some GLP-1 weight-loss medications, like Ozempic and Wegovy, may significantly lessen their effectiveness, according to a new preclinical study from researchers at the Perelman School of Medicine at the ...
May 3, 2026
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Scientists cautiously suggest GLP-1s are safe to use around pregnancy
A new study from the University of St Andrews suggests weight-loss drugs like Ozempic taken around pregnancy do not raise the risk of major birth defects. Published in the American Journal of Obstetrics and Gynaecology, the ...
May 2, 2026
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How unhealthy ultra‑processed foods are designed and marketed to make us crave them
Consumption of ultra-processed foods—including soft drinks, snacks and ready meals—is growing worldwide, despite evidence they are unhealthy.
May 1, 2026
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Weight teasing from different family members linked to harmful health outcomes for adolescents
Weight-related teasing from family members is common among adolescents, and new research from UConn's Rudd Center for Food Policy & Health shows that who the teasing comes from may play an important role in youth health and ...
May 1, 2026
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Two people, same weight, vastly different futures: New tool exposes obesity danger before disease strikes
The study, published in Nature Medicine, shows that future risk of 18 obesity-related diseases can be predicted using 20 commonly collected health measures, such as blood test results and demographic information. The tool ...
Apr 30, 2026
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GLP-1 drugs have long-term benefit for heart health, review suggests
New research has shown that GLP‑1 weight-loss drugs deliver protection against heart attacks, strokes, and premature death over a sustained period of time. Researchers from Anglia Ruskin University (ARU) analyzed data from ...
Apr 30, 2026
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Vegan diet beats Mediterranean diet on emissions and metabolic health in randomized trial
A new randomized clinical trial provides some of the clearest evidence to date that what we eat can meaningfully reshape both human health and the health of the planet. Researchers have found that a low-fat vegan diet reduced ...
Apr 30, 2026
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One molecule, two effects: A new drug concept to treat obesity and type 2 diabetes
A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signaling pathway as a "door ...
Apr 29, 2026
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What to know about GLP-1 drugs for weight loss and health
As many of us know, keeping weight in check can be hard. National numbers certainly reflect this. Rates of overweight and obesity in the U.S. have steadily climbed since the early 1980s. The impact this has had on health ...
Apr 29, 2026
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Bariatric surgery is associated with greater long-term heart risk reduction than weight-loss medications
A Mayo Clinic study has found that both metabolic and bariatric surgery and GLP-1 medications improve cardiovascular health in people with obesity, but surgery was associated with significantly greater reductions in long-term ...
Apr 28, 2026
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