Differentiating cerebral cortical neurons to decipher molecular mechanisms of neurodegeneration
A research team led by Professor Haruhisa Inoue (Department of Cell Growth and Differentiation) derived iPS cells (iPSC) from α-synucleinopathy patients with early-onset familial Parkinson's disease (PD) carrying the α-synuclein ...
23 hours ago
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Genetic variations may predispose people to Parkinson's disease following long-term pesticide exposure, study finds
A new UCLA Health study has found that certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
Apr 25, 2024
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Longest study to date assesses cognitive impairment over time in adults with essential tremor
Essential tremor, a nervous system disorder that causes rhythmic shaking, is one of the most common movement disorders. A new study published in the Annals of Neurology reveals details on the increased risk of mild cognitive ...
Apr 24, 2024
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Improving prospects for people with Parkinson's
In an evolving journey toward understanding and supporting those living with Parkinson's disease, a new report offers fresh insights into the burden it places on those affected.
Apr 22, 2024
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Analyzing the progression in retinal thickness could predict cognitive progression in Parkinson's patients
Although there are still some aspects pending confirmation for its use in the clinical setting, and its resolution needs to be improved slightly, a study by the UPV/EHU and Biobizkaia has shown that a method routinely used ...
Apr 19, 2024
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Battle against fatal neurodegenerative disease advances on two fronts
European researchers are pioneering a vaccine and treatment for amyotrophic lateral sclerosis.
Apr 19, 2024
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AI speeds up drug design for Parkinson's by ten-fold
Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments.
Apr 17, 2024
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New drug may slow rapid progression of Parkinson's disease
Prasinezumab, a monoclonal antibody, is shown to reduce signs of motor deterioration in individuals with Parkinson's disease (PD) who have rapidly progressing disease, as reported in an exploratory analysis of data from a ...
Apr 16, 2024
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Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia
A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.
Apr 16, 2024
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Researchers identify brain region involved in control of attention
Researchers at the University of Iowa in a new study have linked a region in the brain to how humans redirect thoughts and attention when distracted. The connection is important because it offers insights into cognitive and ...
Apr 15, 2024
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Real-world data fill knowledge gap to assess treatment options for infants with spinal muscular atrophy
Findings from a recent study in the Journal of Neuromuscular Diseases demonstrate the effectiveness of disease-modifying treatments (DMTs) in infants with spinal muscular atrophy (SMA). The study's results add further support ...
Apr 15, 2024
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Stirring up emotions: Parkinson's disease alters emotion-related bodily sensations, finds study
Researchers at the University of Turku and Turku University Hospital in Finland have shown that bodily sensations related to emotions are altered by the neurological disorder Parkinson's disease.
Apr 15, 2024
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Subcutaneous infusion of levodopa-carbidopa beneficial for Parkinson's disease
Subcutaneous infusion of ND0612 (a levodopa-carbidopa solution) increases on time without troublesome dyskinesia among patients with Parkinson disease, according to a study published online March 15 in The Lancet Neurology.
Apr 13, 2024
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Wearable sensors for Parkinson's can improve with machine learning, data from healthy adults
Low-cost, wearable sensors could increase access to care for patients with Parkinson's disease. New machine-learning approaches and a baseline of data from healthy older adults improve the accuracy of the results from such ...
Apr 12, 2024
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New hypothesis emerges on Parkinson's disease's origins and spread
The nose or the gut? For the past two decades, the scientific community has debated the wellspring of the toxic proteins at the source of Parkinson's disease. In 2003, a German pathologist, Heiko Braak, MD, first proposed ...
Apr 11, 2024
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Chemicals stored in home garages linked to amyotrophic lateral sclerosis risk
Over the last decade, researchers at the University of Michigan have continued to find that exposure to environmental toxins—from pesticides used in agriculture to volatile organic compounds in the manufacturing industry—is ...
Apr 11, 2024
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Newly discovered genetic variant that causes Parkinson's disease clarifies why the condition develops and how to halt it
Parkinson's disease is a neurodegenerative movement disorder that progresses relentlessly. It gradually impairs a person's ability to function until they ultimately become immobile and often develop dementia. In the U.S. ...
Apr 11, 2024
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Team reports on multifractal detection of the early stages of multiple sclerosis
Multiple sclerosis is a disease mainly associated with the slowing down of information processing and a lack of motor coordination. It is an incurable disease that leads to degeneration of the central nervous system, manifesting ...
Apr 11, 2024
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