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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

Newly discovered cellular trigger could lead to possible therapies for Parkinson's disease

Autophagy is essentially the "rubbish collection" of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists ...

Neuroscience

Exposure to the pesticide rotenone disrupts genes in Parkinson's-linked brain regions

Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new research reveals.

Parkinson's & Movement disorders

Can Amazon Alexa or Google Home help detect Parkinson's?

Computer scientists at the University of Rochester have developed an AI-powered, speech-based screening tool that can help people assess whether they are showing signs of Parkinson's disease, the fastest growing neurological ...

Alzheimer's disease & dementia

Blood plasma reveals shared pathways in neurodegenerative diseases

Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Medical research

Parkinson's disease: Blood changes may occur years before diagnosis

Although Parkinson's disease affects around 1%-2% of people over the age of 65, there is currently no cure. And by the time it is diagnosed—typically by identifying problems with movement, such as slower movements and tremors—the ...

Parkinson's & Movement disorders

Telehealth use up markedly among Parkinson patients

Parkinson disease (PD) symptoms and management practices were markedly affected by COVID-19, according to a study published online Jan. 21 in npj Parkinson's Disease.

Medical research

Geospatial data helps to better understand Parkinson's disease

In a new paper, a team of EPFL spatial-analysis experts and neurologists from Geneva University Hospital (HUG) show that the probability of developing Parkinson's disease is higher in the canton of Geneva's urban centers ...

Neuroscience

Prostate drug associated with lower risk of Parkinson's disease

Taking a particular type of medication to treat enlarged prostate is associated with a reduced risk of developing Parkinson's disease, according to a large observational study led by researchers at the University of Iowa, ...

Medications

New Parkinson's disease therapeutics discovered

Ben-Gurion University of the Negev researchers have discovered that the protein BMP5/7 offers promising therapeutics that could slow down or halt the progression of Parkinson's disease. The findings were published in the ...

Medications

Investigational ALS drug pridopidine enters trial

In 2020, the Sean M. Healey & AMG Center at Massachusetts General Hospital launched the first platform trial for amyotrophic lateral sclerosis (ALS), in which multiple treatments are tested and evaluated simultaneously to ...