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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

Newly discovered cellular trigger could lead to possible therapies for Parkinson's disease

Autophagy is essentially the "rubbish collection" of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists ...

Neuroscience

Exposure to the pesticide rotenone disrupts genes in Parkinson's-linked brain regions

Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new research reveals.

Parkinson's & Movement disorders

Can Amazon Alexa or Google Home help detect Parkinson's?

Computer scientists at the University of Rochester have developed an AI-powered, speech-based screening tool that can help people assess whether they are showing signs of Parkinson's disease, the fastest growing neurological ...

Alzheimer's disease & dementia

Blood plasma reveals shared pathways in neurodegenerative diseases

Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Parkinson's & Movement disorders

Transforming treatments for Parkinson's disease

A revolutionary approach to targeting and treating walking problems in people with Parkinson's disease is being developed at Northumbria University, Newcastle.

Medical research

A novel approach to Parkinson's disease

When scientists study the neuronal mechanisms responsible for neurodegenerative diseases like Parkinson's, they can open the door to promising new approaches to treating those diseases with drugs.

Medical research

Diabetic drug could slow the progression of Parkinson's disease

A hallmark of Parkinson's disease is the degeneration of a group of dopaminergic neurons in the brain, which play key roles in movement initiation and co-ordination. When these neurons degenerate it leads to akinesia (lack ...

Parkinson's & Movement disorders

Eye exam could lead to early Parkinson's disease diagnosis

A simple eye exam combined with powerful artificial intelligence (AI) machine learning technology could provide early detection of Parkinson's disease, according to research being presented at the annual meeting of the Radiological ...

Parkinson's & Movement disorders

Emotion detection in Parkinson's disease

Parkinson's disease is a neurodegenerative disorder that leads to significant disturbances to motor control resulting in involuntary tremor, shuffling gait, muscular rigidity, and other problems. The disease also leads to ...

Parkinson's & Movement disorders

Mimicking brain cells to understand Parkinson's

A device that mimics the brain cells affected by Parkinson's disease could help find new treatments for the condition. The device is described in the Elsevier journal Organs-on-a-Chip. "We have created human neurons that ...

Neuroscience

Leap forward for brain research

Pre-clinical research into deadly brain cancer, Parkinson's, dementia, epilepsy and other major psychiatric and neurological conditions can speed up with the global commercialisation of an advanced neuromedium, called BrainPhys.

Parkinson's & Movement disorders

Common diabetes drugs may prevent Parkinson's

Elevated risk of Parkinson's disease among people with type 2 diabetes appears to be reduced by some medications used to treat their diabetes, finds a new study led by UCL researchers.