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Parkinson's & Movement disorders news
Genetics
New genetic test targets elusive cause of rare movement disorder
Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects ...
Nov 15, 2025
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Removing toxic proteins before they can damage motor neurons
University of Wollongong (UOW) scientists have developed a breakthrough therapy that clears toxic proteins from nerve cells—a discovery that advances the work of the late Professor Justin Yerbury and could transform the ...
Nov 10, 2025
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Q&A: New tech helps Parkinson's patients who have trouble walking
Researchers at UC San Francisco have developed a new way to improve walking for patients with Parkinson's disease using deep brain stimulation and artificial intelligence.
Nov 9, 2025
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Shared synaptic mechanism for Alzheimer's and Parkinson's disease unlocks new treatment possibilities
Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the Okinawa Institute of Science ...
Nov 5, 2025
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How brain lipids help neurons communicate and protect themselves
A University of Alberta research team has discovered a new function for brain molecules known as gangliosides, offering potential new targets for the treatment of Huntington's and other genetic neurological diseases.
Nov 5, 2025
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Slowed by sound: Mouse model of Parkinson's disease shows noise affects movement
In the development of Parkinson's disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson's disease, and established a link between ...
Nov 4, 2025
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The right dose for the brain: Selenomethionine's role in protecting dopaminergic neurons
Dopamine is often called the brain's "motivation molecule," but for me, it represents something deeper, a window into how fragile our neurons can be. The cells that produce dopamine, known as dopaminergic neurons, are among ...
Detailed map of the developing human brain opens new pathways for Parkinson's treatment
Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, ...
Nov 3, 2025
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Personalized care can ease Parkinson's pain
Every 27 minutes, someone in Australia is diagnosed with Parkinson's disease. Best known for its tremors, movement and balance issues, it also brings another, often overlooked burden—persistent pain.
Nov 3, 2025
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New electrical signature of Parkinson's disease identified
What happens in the brain when a person experiences the characteristic movement symptoms of Parkinson's disease? Researchers around the world are seeking answers through various approaches. One of these builds on a treatment ...
Oct 30, 2025
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A newly-discovered mechanism could contribute to the therapeutic effects of deep brain stimulation
Deep brain stimulation (DBS) is a surgical procedure that entails the delivery of high-frequency electrical impulses to specific regions of the brain, via surgically implanted electrodes. While it requires an invasive surgical ...
Common genetic causes across motor neuron diseases identified
Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct. However, an analysis led by investigators ...
Oct 29, 2025
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FDA-approved focused ultrasound treatment for essential tremor now in use as primary treatment for Parkinson's
Barely an hour after being wheeled into a clinical space at Oregon Health & Science University on Aug. 27, an Arkansas woman emerged with vastly improved symptoms of the Parkinson's disease that had plagued her for the past ...
Oct 29, 2025
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Q&A: New drug being reviewed by the FDA to treat Parkinson's disease
The U.S. Food and Drug Administration is reviewing a new Parkinson's disease drug called tavapadon that could give people with the disease more control over their movements.
Oct 29, 2025
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Why does ALS take away body movement? The hidden burden that seals the fate of motor neurons
ALS, also known as Lou Gehrig's disease, is among the most challenging neurological disorders: relentlessly progressive, universally fatal, and without a cure even after more than a century and a half of research. Despite ...
Oct 27, 2025
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New rare genetic disease affecting motor neuron and muscle control identified
An international research team, led by Shinghua Ding at the University of Missouri, has identified a previously unknown genetic disease that affects movement and muscle control.
Oct 27, 2025
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Blood immune cell analysis tested in patients shows promise for early Parkinson's detection
The genetic analysis of a blood sample could become a tool for the early diagnosis of Parkinson's disease, according to an exploratory study led by researchers from the Miguel Hernández University of Elche (UMH). Although ...
Oct 27, 2025
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Advancement for people with Parkinson's in light therapy trial
Australian-founded medical technology company SYMBYX today announced compelling results from a 72-week randomized controlled trial (RCT) demonstrating improvements in a range of Parkinson's disease symptoms. These results, ...
Oct 23, 2025
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Study unveils mechanisms driving axonal accumulation of TDP-43 and associated nerve damage in ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscle wasting and limb paralysis. This neurodegenerative condition results from the gradual destruction of motor neurons, the ...
Women better protected against early neurodegeneration in Parkinson's disease, study reveals
A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson's disease show significantly less brain atrophy—decreased cortical thickness in the brain—than men, ...
Oct 21, 2025
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Study reveals Parkinson's protein clumps rob brain cells of vital energy
A new study led by Rice University's Pernilla Wittung-Stafshede has revealed that protein clumps, or plaques that clog the brain, associated with Parkinson's disease are not merely waste; they can actively drain energy from ...
Oct 21, 2025
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Burden of pain significantly higher in Parkinson's patients
A major QIMR Berghofer-led study has found that Australians living with Parkinson's disease are nearly three times more likely to suffer from chronic pain compared to the general community, with two-thirds of patients experiencing ...
Oct 20, 2025
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Simple blood test shows promise in detecting amyotrophic lateral sclerosis early
New research by UCLA Health has found a simple blood test could provide faster and more accurate diagnosis of ALS by measuring cell-free DNA. The noninvasive test could not only allow neurologists to rule out other neurological ...
Oct 16, 2025
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How fruit flies can help us understand diseases such as ALS
If we can understand exactly how neurodegenerative diseases such as ALS progress in fruit flies, we may also gain valuable insights into how these diseases develop in humans. Research by neurobiologist Marije Been of Radboud ...
Oct 15, 2025
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