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Parkinson's & Movement disorders news

Medications

Weekly injection offers steady Parkinson's medication, reducing need for daily pills

A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Neuroscience

How Parkinson's disease affects emotion recognition of voices

A new study in Neurodegenerative Diseases looks closely at how Parkinson's disease can affect something as everyday and essential as recognizing emotion in someone's voice. The research suggests that both the side of the ...

Parkinson's & Movement disorders

Mouth and gut bacteria linked to brain changes in Parkinson's disease

Scientists have discovered a link between bacteria in the mouth and gut and the progression of cognitive decline in Parkinson's disease. Specific changes in these bacteria, known as the microbiome, have been associated with ...

Medications

Asthma drug could help to treat a rare neurological disorder

The asthma medication theophylline is a suitable drug for treating the rare neurological disorder ADCY5-related dyskinesia, according to a new study by Martin Luther University Halle-Wittenberg (MLU), which was published ...

Autism spectrum disorders

Autism linked to elevated risk of Parkinson's disease

People with an autism diagnosis are at a higher risk of developing Parkinson's disease early in life, a large-scale study from Karolinska Institutet published in JAMA Neurology reports. The researchers believe that the two ...

Parkinson's & Movement disorders

Digital therapeutics can improve Parkinson's control, study finds

The use of PD Neurotechnology's pioneering telemonitoring device to assess Parkinson's Disease (PD) symptoms and inform medication adjustments led to the majority of patients exhibiting improved or stable symptom manifestation, ...

Neuroscience

Parkinson's paradox: When more dopamine means more tremor

Researchers from the Champalimaud Foundation have shed light on the puzzling relationship between dopamine and rest tremor in Parkinson's disease, finding that preserved dopamine in certain brain regions may actually contribute ...

Parkinson's & Movement disorders

Gene therapy protects against motor neuron disease in rats

University of Wisconsin–Madison researchers targeting a group of hereditary neurodegenerative diseases have found success using a gene therapy treatment in an animal model. The approach, which uses CRISPR-Cas9 genome editing ...

Neuroscience

New Huntington's treatment prevents protein aggregation

Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the ...

Parkinson's & Movement disorders

Mouse model reveals liver involvement in muscular dystrophy

A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1—the most prevalent form of adult-onset muscular dystrophy—provides insight into why patients develop fatty liver disease and display hypersensitivity ...

Parkinson's & Movement disorders

Hearing loss linked to increased Parkinson's risk in veterans

Oregon Health & Science University-led researchers have found a correlative link between hearing loss and the development of Parkinson's disease (PD). They find the risk of PD rises somewhat with the severity of hearing loss, ...