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Medical research news

Medical research

Little-known protein appears to play important role in obesity and metabolic disease

With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism. Their discovery, which appears ...

Medical research

Predicting treatment outcome for leishmaniasis

For patients with cutaneous leishmaniasis, a skin infection transmitted by a sand fly that can in some cases lead to painful and disfiguring ulcers, treatment can be grueling. The first-line therapy offered to many requires ...

Medical research

Researchers develop new database of druggable fusion targets

When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play ...

Medical research

Doctors find a cure for rare uncontrollable laughter condition

Laughter is the best medicine, except when it is actually the symptom of an illness. Medical residents at the University of Hawaiʻi (UH) helped to find relief for a man who suffered from nearly a lifelong affliction that ...

Medical research

New cancer treatment not as toxic as others

A QIMR Berghofer study has identified how a newly approved blood cancer drug works and found the treatment is better than other drugs at targeting cancer stem cells while causing minimal damage to healthy cells.

Medical research

In science, it's better to be curious than correct

I'm a geneticist. I study the connection between information and biology—essentially what makes a fly a fly and a human a human. Interestingly, we're not that different. I've been a professional geneticist since the early ...

Medical research

Cellular calpain proteases can cleave the enteroviral polyprotein

Enteroviruses are small, non-enveloped RNA viruses, which belong to the family of picornaviruses. Although most of the diseases that enteroviruses cause are symptomless or mild, enteroviruses are the most common viruses infecting ...

Medical research

Complex organ models grown in the lab

Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

Medical research

Cell death or cancer growth: A question of cohesion

Activation of CD95, a receptor found on all cancer cells, triggers programmed cell death—or does the opposite, namely stimulates cancer cell growth. Scientists from the German Cancer Research Center (DKFZ) have now shown ...

Medical research

How gene-edited white blood cells are helping fight cancer

For the first time in the United States, a gene editing tool has been used to treat advanced cancer in three patients and showed promising early results in a pilot phase 1 clinical trial. So far the treatment appears safe, ...

Medical research

Cryptosporidium: Hot on the trail of a new anti-infective

Developed countries and resource-poor nations alike report Cryptosporidium infections but doctors in nations rich and poor are stymied in efforts to effectively treat it in extremely vulnerable patients—particularly babies—for ...

Medical research

Respiratory syncytial virus transmission in the Middle East

Human respiratory syncytial virus (RSV) is a primary cause of lower respiratory tract infections among young children worldwide, and leads to 60,000 deaths globally each year. A vaccine does not yet exist, although several ...

Medical research

Possible new treatment strategy against progeria

Progeria is a very rare disease that affects about one in 18 million children and results in premature aging and death in adolescence from complications of cardiovascular disease. In a study on mice and human cells, researchers ...

Medical research

Many patients with iNPH develop Alzheimer's disease, too

Up to one in five patients treated for idiopathic normal pressure hydrocephalus, iNPH, also develop Alzheimer's disease, according to a new study from the University of Eastern Finland and Kuopio University Hospital. The ...