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Why older mice have smaller offspring—and how sex may play a role

A study by University of Manchester scientists has revealed some of the mechanisms which may explain why older mice are more likely to give birth to offspring that have not grown to their full potential in the womb.

Medical research

Research gap discovered: 1 in 21 adults affected by mental disorders omitted from global health study

Mental disorders that cause physical symptoms are not included in a major health trends study, despite them impacting as many as 1 in 21 adults, researchers have found.

Medical research

Opt-out organ donation policies may reduce organ supply

Every day, 17 Americans die while waiting for an organ transplant. Opt-out organ donation policies, which enroll everyone into post-mortem donation programs by default unless people choose to opt out, have been touted as ...

Medical research

A 'bird's eye view' of how human brains operate

A new study provides the best evidence to date that the connection patterns between various parts of the human brain can tell scientists the specialized functions of each region.

Medical research

AI helps scientists correct mistakes in medical studies

Randomized, controlled clinical trials are crucial for telling whether a new treatment is safe and effective. But often scientists don't fully report the details of their trials in a way that allows other researchers to gauge ...

Medical research

Scientists find cells that know when, where and how to grow teeth

Tooth development is a dynamic process that involves the stages of the bud, the cap, and the bell, followed by root development and subsequent tooth formation. Processes such as the bud-to-cap transition are mediated by epithelial-mesenchymal ...

Medical research

Blood analyses in dogs could provide insights into human aging

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

Medical research

Pulse oximeter index offers non-invasive guides for fluid therapy

A prospective study conducted at Avicenna University Hospital (Cadi Ayyad University) suggests that the plethysmographic perfusion index (PPI), a noninvasive parameter derived from pulse oximetry, can help identify fluid ...