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Microbial allies: Bacteria help fight against cancer

An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Cologne have discovered that microbes associated with tumors produce a ...

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Identifying the interactions that drive cell migration in brain cancer

To move forward or migrate, the different cells in our body must exert forces or interact with their surrounding environment. Interestingly, however, a fault in these interactions can also be the reason for the spread of ...

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Missing Y gene linked to male infertility

University of Hawaiʻi at Mānoa scientists have uncovered a direct link between a missing Y chromosome gene and male infertility. Their new research reveals that deleting this single gene in mice not only caused infertility ...

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New tool helps identify unreliable research trials

An international group of researchers has developed a new tool that can help identify problematic randomized controlled trials (RCTs), including fraudulent studies, where there are serious concerns about trustworthiness.

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Weight-loss drug semaglutide shown to reduce cocaine use in rats

Scientists have found that the diabetes/weight loss drug semaglutide, sold commercially under brand names like Ozempic and Wegovy, significantly reduces cocaine-seeking behavior in rats. This work needs to be confirmed in ...

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Pioneering strategy may keep breast cancer from coming back

A first-of-its-kind clinical trial has shown it's possible to identify breast cancer survivors who are at higher risk of their cancer coming back due to the presence of dormant cancer cells and to effectively treat these ...

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Could octopuses hold the key to curing cancer?

Scientific breakthroughs often emerge from unexpected and unlikely places. The development of penicillin was an accident, Velcro was inspired by plant burrs and multiple cancer treatments have been developed from sea sponges.

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Adjusting drug timing can boost fertility, study suggests

Researchers at Osaka Metropolitan University have found that changing the timing of fertility drugs to match the follicle maturity period significantly increases the number of ovulated oocytes—the cells that develop into ...

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How a gift card could help speed up Alzheimer's clinical research

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer's disease clinical trials, a new USC study published in JAMA Health Forum finds.

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CaMKIIα redox mechanism revealed as key to learning and memory

A research team led by Prof. Chen Chang from the Institute of Biophysics of the Chinese Academy of Sciences, in collaboration with Prof. Huang Zhangjian of China Pharmaceutical University, has uncovered a previously unknown ...

Medical research

How the body's cells change shape to deal with wounds

The body's cells change their shape to close gaps such as wounds—with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals.

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Geroscience: Rethinking how medicine can approach aging

A review published in the journal JAMA highlights innovative strategies to slow the biological aging process, an emerging approach with significant potential to prevent or delay multiple chronic diseases at once, one of the ...