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Population-specific genetic risk scores advance precision medicine for Han Chinese populations

Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such ...

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New on-switch for pain signaling pathway could lead to safer treatment and relief

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead to safer, more effective ...

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Research unveils new insights on face blindness

For most of us, it happens automatically: we recognize a face in a split second. But for people with developmental prosopagnosia—also known as face blindness—recognizing people is a daily challenge.

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Wearable health technology brings research closer to people

At the University of Oulu in Finland, researchers are exploring new ways to utilize microwave technology in monitoring and assessing health conditions. The results of experiments conducted with realistic models are promising.

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French scientists probe mRNA's potential to fight cancer

Inside a lab in the French city of Orleans, scientists are testing out the limits of molecules in our body called messenger RNA—best known for being used in COVID-19 vaccines—in the hopes of finding a breakthrough treatment ...

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Key protein for healing nerve damage reveals a dual role

Nerve damage can be an unfortunate side effect from an accident, illness or even certain treatments, like chemotherapy. Fortunately, the peripheral nervous system can heal itself to a certain extent, albeit very slowly. Researchers ...

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How cancer cells 'break through' tight tissue gaps

Aggressive cancer cells are masters of movement. When they spread through the body, they cause metastasis, which significantly reduces a person's chance of survival. For this spreading to take place, they can switch between ...

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New study identifies part of brain animals use to make inferences

Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings—for instance, squirrels understand that certain ...

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Non-opioid pain relief: Brain's 'cleanup crew' reveals a new target

Chronic pain is a daily reality for millions of Americans, interfering with their everyday activities and quality of life. An estimated 24.3% of adults in the United States experienced chronic pain in 2023, and current treatment ...

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Researcher out to solve mystery of migraine

Often dismissed as a minor ailment, migraine is a debilitating neurological disease affecting hundreds of thousands of New Zealanders. At the University of Otago's School of Biomedical Sciences, world-leading research by ...

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Opt-out organ donation policies may reduce organ supply

Every day, 17 Americans die while waiting for an organ transplant. Opt-out organ donation policies, which enroll everyone into post-mortem donation programs by default unless people choose to opt out, have been touted as ...

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A 'bird's eye view' of how human brains operate

A new study provides the best evidence to date that the connection patterns between various parts of the human brain can tell scientists the specialized functions of each region.

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AI helps scientists correct mistakes in medical studies

Randomized, controlled clinical trials are crucial for telling whether a new treatment is safe and effective. But often scientists don't fully report the details of their trials in a way that allows other researchers to gauge ...

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Scientists find cells that know when, where and how to grow teeth

Tooth development is a dynamic process that involves the stages of the bud, the cap, and the bell, followed by root development and subsequent tooth formation. Processes such as the bud-to-cap transition are mediated by epithelial-mesenchymal ...

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Blood analyses in dogs could provide insights into human aging

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.