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Preventing overhydration: Study uncovers a neural circuit that prompts mice to stop drinking

Identifying the neural mechanisms that support the regulation of vital physiological processes, such as drinking, eating and sleeping, is a long-standing goal within the neuroscience research community. As the disruption ...

Medical research

Gut microbiome affects alcohol preference by influencing brain's reward system

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have found a surprising connection between a fungus associated with alcohol use disorder and the brain's dopamine reward ...

Medical research

Cardamom seeds revealed as potential source of antiviral treatment

Plant-based materials have traditionally been used to treat a variety of viral infections. Now, researchers have found that cardamom seed extract, as well as its main bioactive ingredient, 1,8-cineole, can have potent antiviral ...

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mRNA therapy restores sperm production and fertility in mice

For many couples facing infertility, medicine offers a range of solutions. But for men with non-obstructive azoospermia (NOA)—a genetic condition where sperm production stalls—options remain limited.

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Ketogenic diet may protect against stress experienced in the womb

Researchers have shown that young rats fed a ketogenic diet—a diet with high fat and low carbohydrates—are protected from the lasting experience of pre‑natal stress. This work, which has not yet been confirmed in humans, ...

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A global standard to measure outcomes in dengue treatment trials

The first global standard that harmonizes what outcomes to measure in dengue treatment trials has been published Oct. 7 in The Lancet Infectious Diseases. Co-led by researchers at King's and the University of Oxford, this ...

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To get representative health data, researchers hand out fitbits

A study finds that a representative sample of people given wearable data collection devices provides more equitable and accurate health data than larger convenience samples of people who already own wearable devices. Leveraging ...

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How cell skeleton defects can teach immunology

For immune cells, the actin cytoskeleton is more than a structural scaffold. Immune cells can migrate to sites of infection or form precise, short-lived contacts with other cells, by constantly reshaping their actin cytoskeleton. ...

Medical research

Old data can transform the future of health care

Patient preference studies (research into what patients value in their treatment) are increasingly used to inform drug development and regulatory approval decisions. But these studies are expensive and time-consuming to conduct. ...

Medical research

Microbial allies: Bacteria help fight against cancer

An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Cologne have discovered that microbes associated with tumors produce a ...

Medical research

Missing Y gene linked to male infertility

University of Hawaiʻi at Mānoa scientists have uncovered a direct link between a missing Y chromosome gene and male infertility. Their new research reveals that deleting this single gene in mice not only caused infertility ...

Medical research

New tool helps identify unreliable research trials

An international group of researchers has developed a new tool that can help identify problematic randomized controlled trials (RCTs), including fraudulent studies, where there are serious concerns about trustworthiness.