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Medical research news
Medical research
Finances leading factor for some cancer patients not enrolling in potentially life-saving clinical trials, study shows
A study by Case Western Reserve University and University Hospitals researchers has overturned long-held assumptions about why more cancer patients don't enroll in clinical trials that could potentially save their lives.
Dec 18, 2025
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Medical research
Researchers identify 166 human pluripotent stem cell lines available for use in clinical applications
To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental ...
Dec 18, 2025
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How embryos and the uterus 'talk' during implantation
A new study shows that the embryo and the uterine lining conduct an active "conversation" from the very earliest stages of implantation. They engage in a back and forth of tiny packages called extracellular vesicles and lipid ...
Dec 17, 2025
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Some ventilator settings can double airway stress
Mechanical ventilation saves lives, but the airflow it produces inside an intubated airway can also shape conditions linked to complications during long-term support. In a recent study, SUNY Polytechnic Institute faculty ...
Dec 17, 2025
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Clinical trial suggests knowing HIV 'viral load' doesn't improve number of patients seeking needed care
According to the U.S. Centers for Disease Control and Prevention (CDC) and other sources, there are approximately 1.2 million people living with HIV in the United States, and another 1.2 to 2.2 million who are at highest ...
Dec 16, 2025
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Structure of dopamine-releasing neurons relates to the type of circuits they form for smell-processing, study finds
Closely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical structure.
Dec 16, 2025
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Gut bacteria from amphibians and reptiles achieve complete tumor elimination in preclinical model
A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes ...
Dec 15, 2025
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Neurons use physical signals, not electricity, to stabilize communication
Every movement you make and every memory you form depends on precise communication between neurons. When that communication is disrupted, the brain must rapidly rebalance its internal signaling to keep circuits functioning ...
Dec 15, 2025
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Accelerating drug combination discovery with machine learning
Discovering effective drug combinations may now be easier thanks to a screening platform made public today by St. Jude Children's Research Hospital scientists. Many diseases, including cancers, require combinations of drugs ...
Dec 15, 2025
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How the NIH became the backbone of American medical research and a major driver of innovation and economic growth
As a young medical student in 1975, I walked into a basement lab at the National Institutes of Health in Bethesda, Maryland, to interview for a summer job.
Dec 15, 2025
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Scientists develop mini human heart organoid that mimics atrial fibrillation
Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular and often fast heartbeat, it's been at least 30 years since any new treatments have been developed. This is because ...
Dec 14, 2025
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FDA drug trials exclude a widening slice of Americans, research reveals
A new study finds just 6% of clinical trials used to approve new drugs in the U.S. reflect the country's racial and ethnic makeup, with an increasing trend of trials underrepresenting Black and Hispanic individuals.
Dec 13, 2025
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Biomedical authors often call a reference 'recent'—even when it is decades old, analysis shows
Authors in biomedical journals frequently describe cited evidence as "recent," yet the actual age of the references behind these phrases has rarely been measured.
Dec 11, 2025
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Blocking collagen signaling boosts drug delivery in pancreatic cancer
Pancreatic cancer is one of the deadliest malignancies, with survival rates remaining dismally low despite major advances in oncology. One of the key reasons lies in the disease's unique fibrotic microenvironment—a dense, ...
Dec 11, 2025
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Rats may seek cannabis to cope with stress
It isn't just people—when given the chance, rats may also use cannabis to cope with stress, according to a study by researchers at Washington State University.
Dec 11, 2025
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Fake participants and bots threaten quality of online research data
Recruiting participants for injury and violence-related studies can be challenging. Online qualitative data collection can increase accessibility for some participants, expand a study's reach to potential participants, offer ...
Dec 11, 2025
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Diversity language in US medical research agency grants declined 25% since 2024, analysis finds
Words reflecting diversity language have appeared less frequently in grants awarded by the National Institutes of Health (NIH) since the 2024 US presidential election, with a 25% relative decrease between January 2024 and ...
Dec 11, 2025
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Helping ICU patients regain independence: How early rehabilitation can speed recovery
A multicenter study across Japan found that ICU patients receiving more intensive rehabilitation regained independence faster after critical illness. Among 121 patients on mechanical ventilation, higher rehabilitation dose ...
Dec 11, 2025
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Key protein behind necroptotic cell death could drive new treatment strategies
Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their findings, reported in Nature, ...
Dec 10, 2025
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Mini brains, big questions: Science is racing ahead of ethics
In a little over ten years, organoid models—miniature, lab-grown clusters of cells that imitate real organs—have transformed how we study human development and disease while accelerating drug discovery. As a bonus, they've ...
Dec 10, 2025
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Cancer signaling discovery reveals potential path to more effective cancer drugs
Interrupting one function of a protein that plays a key role in cell signaling could enable the development of new cancer treatments, according to a study led by Dr. Martin Taylor at the Warren Alpert Medical School of Brown ...
Dec 10, 2025
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Growth hormone directly regulates stem cells in bone growth plates, revealing a delicate balance
Researchers at the University of Gothenburg can now demonstrate previously unexplained processes behind growth therapy. It involves hormonal mechanisms at the cellular level, with focus on a sensitive balance between stem ...
Dec 9, 2025
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Genetic testing reveals often-overlooked fungal infections in California clinics
A new study reveals that a rarely-diagnosed and frequently drug-resistant species, Aspergillus tubingensis, may be one of the most common causes of fungal infections in Southern California.
Dec 5, 2025
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Key kidney sensor that helps control fluid balance identified
A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...
Dec 4, 2025
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From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer
Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...
Dec 4, 2025
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