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Medical research
How statins harm muscles—and how to stop it
Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness ...
17 hours ago
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Medical research
Strategies to keep drug discovery research alive in the US despite funding cuts
In the face of US federal funding cuts, biomedical researchers propose strategies for continued progress in drug discovery. Publishing in Trends in Pharmacological Sciences, their recommendations include harnessing AI and ...
17 hours ago
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Advancing patient-reported outcomes in cancer clinical trials
The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...
Nov 25, 2025
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Pill form of semaglutide fails to slow Alzheimer's in large trial
A pill version of semaglutide, the ingredient in Ozempic and Wegovy, did not slow the progress of Alzheimer's disease, drugmaker Novo Nordisk announced on Nov. 24.
Nov 25, 2025
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Two parallel blood formation systems produce different immune and blood cells
It has only recently become known that two parallel systems of blood formation exist in the body, originating from different precursor cells. Researchers at the German Cancer Research Center (DKFZ) have developed a method ...
Nov 24, 2025
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Doctors still outperform AI in clinical reasoning, study shows
AI may ace multiple-choice medical exams, but it still stumbles when faced with changing clinical information, according to research in the New England Journal of Medicine.
Nov 24, 2025
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Microprotein adipogenin found to regulate fat storage in cells
A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows. ...
Nov 24, 2025
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Chemerin receptor structures disclose new mechanism of lipid metabolism
Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity and diabetes. In addition, it plays a critical role in inflammation as a ...
Nov 21, 2025
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Population-specific genetic risk scores advance precision medicine for Han Chinese populations
Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such ...
Nov 21, 2025
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New on-switch for pain signaling pathway could lead to safer treatment and relief
Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead to safer, more effective ...
Nov 20, 2025
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French scientists probe mRNA's potential to fight cancer
Inside a lab in the French city of Orleans, scientists are testing out the limits of molecules in our body called messenger RNA—best known for being used in COVID-19 vaccines—in the hopes of finding a breakthrough treatment ...
Nov 20, 2025
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Wearable health technology brings research closer to people
At the University of Oulu in Finland, researchers are exploring new ways to utilize microwave technology in monitoring and assessing health conditions. The results of experiments conducted with realistic models are promising.
Nov 20, 2025
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Research unveils new insights on face blindness
For most of us, it happens automatically: we recognize a face in a split second. But for people with developmental prosopagnosia—also known as face blindness—recognizing people is a daily challenge.
Nov 20, 2025
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Key protein for healing nerve damage reveals a dual role
Nerve damage can be an unfortunate side effect from an accident, illness or even certain treatments, like chemotherapy. Fortunately, the peripheral nervous system can heal itself to a certain extent, albeit very slowly. Researchers ...
Nov 19, 2025
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Phase II clinical trial results show potential to shorten TB treatment time
New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve ...
Nov 19, 2025
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Targeted protein degradation: A new way to combat harmful proteins in tumor cells
A new active substance attacks a key protein in tumor cells, leading to complete degradation. In cell experiments, this caused cancer cells to lose their protection and die. The active substance was developed by researchers ...
Nov 18, 2025
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Bone marrow model built entirely from human cells can reduce animal testing
Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this cellular complexity in the ...
Nov 18, 2025
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How cancer cells 'break through' tight tissue gaps
Aggressive cancer cells are masters of movement. When they spread through the body, they cause metastasis, which significantly reduces a person's chance of survival. For this spreading to take place, they can switch between ...
Nov 18, 2025
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NIH grant terminations leave thousands without access to care, study finds
Thousands of clinical trial participants lost access to important medical studies this year after the Trump administration terminated hundreds of National Institutes of Health (NIH) grants, according to new research published ...
Nov 18, 2025
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Disrupting bacterial 'chatter' could tip the balance for better oral health
Like all living things, bacteria adapt to survive. Over time, bacteria have been developing resistance to common antibiotics and disinfectants, which poses a growing problem for health care and sanitation. However, many species ...
Nov 17, 2025
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Scientists identify two key targets of common cold virus
Scientists were pleased when they learned more about how the common cold gains a foothold in the body, identifying key cellular checkpoints that are important targets of the virus.
Nov 17, 2025
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New study identifies part of brain animals use to make inferences
Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings—for instance, squirrels understand that certain ...
Nov 17, 2025
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Clinical trial countries often left without new medicines they helped test
A new study led by Yale's Jennifer Miller, Ph.D., found that medicines are not physically accessible in many of the countries where they are tested for FDA approval. The findings were published in JAMA Internal Medicine.
Nov 17, 2025
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Non-opioid pain relief: Brain's 'cleanup crew' reveals a new target
Chronic pain is a daily reality for millions of Americans, interfering with their everyday activities and quality of life. An estimated 24.3% of adults in the United States experienced chronic pain in 2023, and current treatment ...
Nov 17, 2025
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Blood tests and sputum analysis help predict COPD exacerbation risks
A research team from the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has highlighted recent advances in understanding and managing COPD, particularly in relation to its exacerbations. The key findings ...
Nov 17, 2025
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