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T-bet protein found essential for maintaining flu-fighting memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen ...

Medical research

Olorofim Phase IIb trial shows efficacy in invasive fungal disease for patients with limited treatment options

Researchers from KU Leuven, the University of California Davis Medical Center, the University of Cologne, and over 20 collaborating institutions report that the antifungal olorofim demonstrated efficacy and tolerability in ...

Medical research

New AI model could help scientists pinpoint signs of cancer cells

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, ...

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A new drug could soon help treat cancer and viral infections

An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where ...

Medical research

When stem cells feel the squeeze, they start building bone

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

Medical research

Scientists create biological 'artificial intelligence' system

Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said ...

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Preclinical study unlocks a mystery of rapid mouth healing

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered ...

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Probiotics with protective armor could boost gut health

A research team has developed a new method for encapsulating probiotics. They used nanoparticles formed by antisolvent precipitation to protect the probiotics, and tested the probiotics in lab simulations and animal experiments ...

Medical research

Experts issue new ethical standards for body donation programs

A report in the journal Anatomical Sciences Education outlines best practices and standards for human body donation programs across the United States, which accept whole body donations after death for research and education.

Medical research

New research reveals how the body clock regulates inflammation

New research from RCSI University of Medicine and Health Sciences has explained how the body's internal clock influences the inflammatory process of the immune system. The findings describe how immune cells, called macrophages, ...

Medical research

Studies reveal evolution of paramagnetic rim lesions in MS

In recent years, researchers studying multiple sclerosis have concluded that white matter lesion volume in the brain, long considered the best way to monitor MS disease progression, may not be the most accurate predictor ...