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T-bet protein found essential for maintaining flu-fighting memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen ...

Medical research

Olorofim Phase IIb trial shows efficacy in invasive fungal disease for patients with limited treatment options

Researchers from KU Leuven, the University of California Davis Medical Center, the University of Cologne, and over 20 collaborating institutions report that the antifungal olorofim demonstrated efficacy and tolerability in ...

Medical research

New AI model could help scientists pinpoint signs of cancer cells

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, ...

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A new drug could soon help treat cancer and viral infections

An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where ...

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When stem cells feel the squeeze, they start building bone

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

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Scientists create biological 'artificial intelligence' system

Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said ...

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Preclinical study unlocks a mystery of rapid mouth healing

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered ...

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Hypovolemic phlebotomy beneficial before liver resection

For patients undergoing liver resection, hypovolemic phlebotomy reduces perioperative red blood cell transfusions compared with usual care, according to a study published online Dec. 9 in The Lancet Gastroenterology and Hepatology.

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Psychedelic therapy research calls for better reporting

Psychedelic-assisted psychotherapy is gaining attention as a promising approach to treat patients with mental disorders for whom conventional treatments have been insufficient. A new collaborative study by researchers at ...

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Scientists reveal how COVID-19 variants hijack human cells

Scientists at the University of Helsinki, University of Eastern Finland and University of Turku are investigating the intricate ways in which various SARS-CoV-2 variants, like delta and omicron, interact with human cells ...

Medical research

Unexpected discovery revives abandoned breast cancer treatment

A recent study led by Lund University in Sweden has found that some patients with aggressive breast cancer can be helped by a targeted cancer treatment that had been under development but was shelved. The study is important ...

Medical research

Bioprinting technique creates functional tissue 10x faster

Three-dimensional (3D) printing isn't just a way to produce material products quickly. It also offers researchers a way to develop replicas of human tissue that could be used to improve human health, such as building organs ...

Medical research

Unique experiment sends T-cells into space

On 26 November, an experiment in a sounding rocket was launched at Esrange Space Center in Kiruna, Sweden, by a research group at the Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet.

Medical research

Mouse study captures aging process at the cellular level

As muscles age, their cells lose the ability to regenerate and heal after injury. Cornell Engineering researchers have created the most comprehensive portrait to date of how that change, in mice, unfolds over time and across ...

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New protocol targets fraud in rural online studies

A new protocol can detect and remove fake data created by bots and humans attempting to enroll in online research studies, in order to prevent biased results and unwarranted payments to bad actors—the first such protocol ...

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HIV: There's hope for a cure—where we stand now

With the help of new scientific and technological developments, the HIV/Aids research community is increasingly turning to an ambitious goal: finding a cure for HIV/Aids.