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Key kidney sensor that helps control fluid balance identified

A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...

Medical research

From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...

Medical research

Why stress can make your hair fall out: A two-part reaction

It's well known that stress can trigger hair loss. A new paper explores how this happens and how our response to stress can have long-term consequences for our scalps, research that may eventually yield insights into autoimmune ...

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Internet and lack of trust threatens patient–doctor bond

Physicians have worked to earn the trust of their patients for nearly 2,400 years, dating back to the days of Hippocrates, the father of Western medicine. Lucky for Hippocrates that his patients didn't have internet access.

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Stem cell organoids mimic aspects of early limb development

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.

Medical research

The 'Miracle Mineral Solution'—amazing cure or toxic illusion?

Miracle Mineral Solution, also known as MMS, has been marketed for years as a purported miracle cure for various conditions, including cancer, autism, and COVID-19. MMS is the marketing name for sodium chlorite (NaClO₂), ...

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When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

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How statins harm muscles—and how to stop it

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness ...

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Advancing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...

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Microprotein adipogenin found to regulate fat storage in cells

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows. ...

Medical research

Cell-permeable peptide shows promise in nerve cell regeneration

Each year, according to the National Institutes of Health (NIH), millions of people in the U.S. are affected by spinal cord and traumatic brain injuries, along with neuro-developmental and degenerative diseases such as ADHD, ...

Medical research

Kratom to be tested for addiction risk in clinical trial

Popular for its stimulating and pain-relieving properties, the herb kratom can be as easy to buy as a bag of chips in many parts of the U.S. That's also raised questions about whether kratom should be more closely regulated.

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A 3D lung model raises the bar for research

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depends on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct ...

Medical research

NIH research funding drops $1B under Trump administration

Federal funding for medical research has dropped by roughly $1 billion this year, raising alarm among universities, medical centers and lawmakers who warn the shortfall could slow progress in cancer, diabetes and heart disease ...

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First transgenic primate model created for hepatitis B research

Researchers at Oregon Health & Science University have developed the first transgenic nonhuman primate model—genetically modified to carry a human gene—for studying hepatitis B virus. The breakthrough could lead to the ...