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Association between trust of researchers and willingness to participate in Alzheimer's disease biomarker research

A new study has found that trust in researchers is the strongest factor influencing whether older adults are willing to participate in Alzheimer's disease and related dementia (ADRD) biomarker research. In a survey of 399 ...

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New trial aims to advance research into Strep A vaccine development

A new human challenge trial under way in Melbourne aims to advance research into Strep A, accelerating efforts toward the development of a vaccine.

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Microbial allies: Bacteria help fight against cancer

An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Cologne have discovered that microbes associated with tumors produce a ...

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Missing Y gene linked to male infertility

University of Hawaiʻi at Mānoa scientists have uncovered a direct link between a missing Y chromosome gene and male infertility. Their new research reveals that deleting this single gene in mice not only caused infertility ...

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New tool helps identify unreliable research trials

An international group of researchers has developed a new tool that can help identify problematic randomized controlled trials (RCTs), including fraudulent studies, where there are serious concerns about trustworthiness.

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Weight-loss drug semaglutide shown to reduce cocaine use in rats

Scientists have found that the diabetes/weight loss drug semaglutide, sold commercially under brand names like Ozempic and Wegovy, significantly reduces cocaine-seeking behavior in rats. This work needs to be confirmed in ...

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Pioneering strategy may keep breast cancer from coming back

A first-of-its-kind clinical trial has shown it's possible to identify breast cancer survivors who are at higher risk of their cancer coming back due to the presence of dormant cancer cells and to effectively treat these ...

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Cellular senescence may be to blame for some diseases

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, telomere shortening and oxidative ...

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Researchers link CAR-T cell aging to cancer relapse

Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the engineered immune cells age and lose their ...