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A new drug could soon help treat cancer and viral infections

An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where ...

Medical research

Shorter-form messaging may be preferable for trial recruitment

Shorter-form messaging seems to be preferable for recruiting participants to enroll in clinical trials, according to a research letter published online June 25 in the Journal of the American Medical Association.

Medical research

When stem cells feel the squeeze, they start building bone

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

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Scientists create biological 'artificial intelligence' system

Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said ...

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Preclinical study unlocks a mystery of rapid mouth healing

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered ...

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How modified RNA tricks the innate immune system

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA—such as that from ...

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Nanoparticles extend glioblastoma survival in phase one trial

Despite decades of research to develop effective treatments, the median survival for glioblastoma—the most common malignant primary brain tumor in adults—is just 15–18 months after diagnosis. One reason for this grim ...

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New study validates lower limits of human heat tolerance

A study from the University of Ottawa's Human and Environmental Physiology Research Unit (HEPRU) has confirmed that the limits for human thermoregulation—our ability to maintain a stable body temperature in extreme heat—are ...

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Barriers to including non-English speakers in research explained

Health researchers omit including speakers of languages other than English (LOE) in their studies due to lack of training, challenges securing interpreter services, budget constraints and other barriers, according to a new ...

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Study reveals how Chagas parasite invades human cells

Researchers from Auburn University, in a landmark collaboration with Brazil's Oswaldo Cruz Foundation (FIOCRUZ), the world's leading research institution on Chagas Disease, have published a significant study in the journal ...

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Cyanide plays a major role in the human body, study reveals

Cyanide is a highly lethal chemical that has been used in warfare and poisonings for centuries—that was the general consensus on the naturally occurring chemical up until spring 2025. But in a global study published in ...

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The role of journals in medical misconduct

Editors of medical journals deal with allegations of research misconduct, defined by the Office of Research Integrity (ORI) in the U.S. as fabrication, falsification and plagiarism. Research misconduct threatens the validity ...

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White House halts long-running HIV research network for youth

A study funded by the National Institutes of Health that would test if an antibiotic can prevent sexually transmitted infections in women has been terminated by the Trump administration as part of its ongoing attempt to halt ...

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Chinese doctors implant pig liver in human for first time

Chinese doctors said Wednesday that they had transplanted a liver from a genetically modified pig into a brain-dead human for the first time, raising hopes of a life-saving donor option for patients in the future.

Medical research

New protein target identified for muscle repair and regeneration

For millions of people, losing muscle isn't just about weakness; it's about losing independence. Whether caused by Duchenne muscular dystrophy, aging or other degenerative conditions, muscle loss can make everyday activities—like ...