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Medical research news
Medical research
Coronavirus replication relies on newly identified host enzyme, study finds
A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated during infection with human ...
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Medical research
Why older mice have smaller offspring—and how sex may play a role
A study by University of Manchester scientists has revealed some of the mechanisms which may explain why older mice are more likely to give birth to offspring that have not grown to their full potential in the womb.
Nov 6, 2025
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Scientists complete first drafts of developing mammalian brain cell atlases
A global consortium of scientists has created the first and most detailed "developmental maps" of the mammalian brain (from mouse to human) to date, taking the first critical steps in unraveling the mystery of early brain ...
Nov 5, 2025
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Research gap discovered: 1 in 21 adults affected by mental disorders omitted from global health study
Mental disorders that cause physical symptoms are not included in a major health trends study, despite them impacting as many as 1 in 21 adults, researchers have found.
Nov 5, 2025
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Global Decade Report reveals breakthroughs in advanced breast cancer but exposes a widening global equity gap
The ABC Global Alliance today launched the Advanced Breast Cancer (ABC) Global Decade Report 2015–2025—a global assessment revealing a decade of remarkable scientific progress that has transformed ABC care for some patients ...
Nov 5, 2025
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Reconstruction of mutated C9orf72 gene sheds light on abnormal protein synthesis in neurodegenerative disorders
Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative disorders, as reported by researchers from Science Tokyo.
Nov 5, 2025
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How to identify and prevent fraudulent participants in health research
The rise in virtual research since the COVID-19 pandemic has created opportunities for researchers to expand and diversify clinical trials, but it has also opened up avenues for fraudulent participation in these studies.
Nov 5, 2025
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Slowed by sound: Mouse model of Parkinson's disease shows noise affects movement
In the development of Parkinson's disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson's disease, and established a link between ...
Nov 4, 2025
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'Rotten egg' gas could be the answer to treating nail infections, say scientists
Hydrogen sulfide, the volcanic gas that smells of rotten eggs, could be used in a new treatment for tricky nail infections that acts faster and with fewer side effects, according to scientists at the University of Bath and ...
Nov 3, 2025
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Evolutionary comparison points to pigs as superior models for human pancreas and diabetes research
Pancreas development in pigs resembles humans much more closely than does the established mouse model. An international team headed by Helmholtz Munich and the German Center for Diabetes Research (DZD) has now produced a ...
Nov 3, 2025
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'Molecular glues' and 'bumpers' offer new hope for precision medicines
New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest ...
Nov 2, 2025
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Astringent, sharper mind: Flavanols can trigger brain activity for memory and stress response
Astringency is a dry, puckering, rough, or sandpapery sensation in the mouth caused by plant-derived polyphenols. Polyphenols, including flavanols, are well known for risk reduction in cardiovascular diseases.
Nov 1, 2025
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Opening the door to a vaccine for multiple childhood infections
A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.
Oct 31, 2025
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Experts urge clinicians to address sex-based disparities in sepsis treatment
Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability—especially that associated ...
Oct 31, 2025
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Hundreds of animal studies on brain damage after stroke flagged for problematic images
A new study has identified over 240 scientific publications on animal models of hemorrhagic stroke that contain potentially problematic images, thereby raising concerns about the trustworthiness of the body of literature ...
Oct 30, 2025
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Discovery of viral entry routes and decoy molecules could block yellow fever and encephalitis
Researchers at Washington University School of Medicine in St. Louis have identified central routes that two deadly viruses take to invade human cells and have designed decoy molecules that block the infections.
Oct 30, 2025
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First online app for selecting best AI models for treatment of individual organs could help patients and physicians
A team from the Department of Electronics, Information and Bioengineering of the Politecnico di Milano, led by Dr. Andrea Moglia, has developed the first online application that helps identify which artificial intelligence ...
Oct 30, 2025
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Decentralized future: Expanding clinical trials by allowing people to participate from home
As the world becomes more digital, clinical research is evolving. One major change is the rise of decentralized clinical trials, or DCTs. Unlike traditional trials that require participants to visit hospitals or research ...
Oct 30, 2025
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Discovery of 'doorstop' for brain's electrical gates may open path to new therapies for neurodegenerative conditions
As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions ...
Oct 29, 2025
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Clinical trial shows efficacy of bacteriophage therapy for Staphylococcus aureus bacteremia
During IDWeek 2025 in Atlanta, Georgia, Loren G. Miller, MD, MPH, investigator at The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, presented findings from the Phase IIa diSArm study. Dr. Miller ...
Oct 29, 2025
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In drug trials, lack of oversight of research ethics boards could put Canadian patients at risk
New drug approvals by Health Canada are based on the results of clinical trials. But before clinical trials can go ahead, they need to be approved by ethics committees known as Research Ethics Boards (REBs).
Oct 29, 2025
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Animal study links regional PFAS levels to male reproductive impacts
New research from the University of Newcastle has revealed that PFAS levels matching those found in the Williamtown contamination zone could significantly alter male reproductive health in animals—even without visibly damaging ...
Oct 28, 2025
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Opt-out organ donation policies may reduce organ supply
Every day, 17 Americans die while waiting for an organ transplant. Opt-out organ donation policies, which enroll everyone into post-mortem donation programs by default unless people choose to opt out, have been touted as ...
Oct 28, 2025
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WHO's priorities shaped by its reliance on grants from donor organizations, study suggests
The World Health Organization's (WHO's) priorities are being skewed by its increasing reliance on donations from organizations such as the Gates Foundation (previously known as the Bill and Melinda Gates Foundation), which ...
Oct 28, 2025
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Misapplied pharmaceutical model prevents scaling of effective interventions, researcher argues
A new article published in the Journal of Medical Internet Research challenges the foundational research model that has shaped the digital health industry for decades. The article, "From Efficacy to Scale: Addressing Digital ...
Oct 28, 2025
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