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Olorofim Phase IIb trial shows efficacy in invasive fungal disease for patients with limited treatment options

Researchers from KU Leuven, the University of California Davis Medical Center, the University of Cologne, and over 20 collaborating institutions report that the antifungal olorofim demonstrated efficacy and tolerability in ...

Medical research

Advanced microscopy reveals that dopamine operates with surgical precision, not as a broad signal

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates ...

Medical research

New AI model could help scientists pinpoint signs of cancer cells

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, ...

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A new drug could soon help treat cancer and viral infections

An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where ...

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When stem cells feel the squeeze, they start building bone

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

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Scientists create biological 'artificial intelligence' system

Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said ...

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Preclinical study unlocks a mystery of rapid mouth healing

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered ...

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Cyanide plays a major role in the human body, study reveals

Cyanide is a highly lethal chemical that has been used in warfare and poisonings for centuries—that was the general consensus on the naturally occurring chemical up until spring 2025. But in a global study published in ...

Medical research

The role of journals in medical misconduct

Editors of medical journals deal with allegations of research misconduct, defined by the Office of Research Integrity (ORI) in the U.S. as fabrication, falsification and plagiarism. Research misconduct threatens the validity ...

Medical research

White House halts long-running HIV research network for youth

A study funded by the National Institutes of Health that would test if an antibiotic can prevent sexually transmitted infections in women has been terminated by the Trump administration as part of its ongoing attempt to halt ...

Medical research

Chinese doctors implant pig liver in human for first time

Chinese doctors said Wednesday that they had transplanted a liver from a genetically modified pig into a brain-dead human for the first time, raising hopes of a life-saving donor option for patients in the future.

Medical research

New protein target identified for muscle repair and regeneration

For millions of people, losing muscle isn't just about weakness; it's about losing independence. Whether caused by Duchenne muscular dystrophy, aging or other degenerative conditions, muscle loss can make everyday activities—like ...

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How stem cells calm the body's immune response

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An international research team led by Universitätsmedizin Frankfurt and Goethe University has now investigated ...

Medical research

What happens in the male mouse brain during sex

To uncover what drives sexual behavior in animals, researchers studied the brain activity of male mice throughout the series of actions involved in sex leading up to ejaculation. Their results, published in Neuron, show that ...