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Blood test predicts which bladder cancer patients may safely skip surgery

Circulating tumor DNA, or ctDNA, can predict metastatic risk in patients who receive bladder-sparing treatment for muscle-invasive bladder cancer, but it is not a good predictor of local recurrence within the bladder, according ...

6 hours ago

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Study compiles 30 years of adhesion GPCR modulators and their key concentrations

Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly expanding body of knowledge on the therapeutic targeting of these receptors is raising hopes for ...

7 hours ago

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Male sex, older age predict poor outcomes in seniors with HFmrEF/HFpEF

Considerable sex disparities are reported in elderly patients with heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), with male sex and older age predicting poor outcomes, according to a study ...

8 hours ago

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Perioperative enfortumab vedotin + pembrolizumab tied to improved outcomes with bladder cancer

Perioperative enfortumab vedotin plus pembrolizumab and surgery lead to significantly better outcomes among patients with muscle-invasive bladder cancer who are ineligible for cisplatin-based chemotherapy compared with surgery ...

9 hours ago

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