For years, the search for a stem cell donor has felt like a quest for a rare key—one that fits a lock with eight intricate tumblers, each representing a genetic marker. For many patients with blood cancers, especially those ...
Dec 6, 2025
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A study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing ...
Dec 6, 2025
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A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour ...
Dec 6, 2025
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Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according ...
Dec 6, 2025
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Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure. The ...
Dec 6, 2025
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Oxford's Big Data Institute and Nuffield Department of Population Health report that daily step counts may help identify who will later be diagnosed with Parkinson's disease, with lower activity patterns acting as an early ...
Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable bacterial product causes mutations in DNA that have been linked to colorectal cancer. Because it ...
Humans and other animals actively sense their surrounding environment. This entails the deliberate adjustment of motor behavior involved in sensory sampling (i.e., movements of the eyes, ears and hands) in line with the stimulus ...
UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments ...
Dec 5, 2025
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New research published in the journal eNeuro examined whether eliminating a protein that is elevated in the brains of those with Alzheimer's could prevent or reduce damage and behavioral symptoms in a mouse model of Alzheimer's ...
Dec 5, 2025
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