Why anti-cancer drugs do not always live up to expectations

For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The biology looked promising. Many cancers depend on oncogenes that "Bromo- and Extra-Terminal domain" ...

How an overactive immune system can drive cancer

The immune system is designed to protect us against viruses and bacteria. In autoimmune diseases, however, the immune system instead attacks the body's own cells. Conditions such as systemic lupus erythematosus (lupus) and ...

Gut bacteria linked to levels of latent HIV

The composition of gut bacteria appears to be associated with how much latent HIV remains in the blood of people receiving antiretroviral therapy. This is shown in a new study from Karolinska Institutet, published in Gut ...

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