Trials of a new cholesterol-lowering pill have shown promising results for people with heterozygous familial hypercholesterolemia (HeFH), a genetic disorder that leads to high levels of LDL cholesterol.
As we age, the composition and function of proteins in the brain change, affecting how well our brain performs later in life—influencing memory, responsiveness, and the risk of neurodegenerative diseases.
Nov 20, 2025
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A Penn-led team has revealed how hydralazine, one of the world's oldest blood pressure drugs and a mainstay treatment for preeclampsia, works at the molecular level. In doing so, they made a surprising discovery—it can ...
Nov 16, 2025
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Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea. However, ...
Nov 20, 2025
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University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models. The findings ...
Nov 21, 2025
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Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function. The mechanism involves ...
Nov 21, 2025
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Public interest in drugs known as glucagon-like peptide-1 receptor agonists, also called GLP-1 RAs, has surged in recent years, with popular types like semaglutide (sold under brand names like Ozempic and Wegovy) becoming ...
Nov 19, 2025
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The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it. However, the molecular mechanisms driving treatment resistance ...
Nov 19, 2025
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Current cardiac screening tools used to prevent heart attacks fail to identify nearly half of the people who are actually at risk of having one, according to a new study led by Mount Sinai researchers.
Nov 21, 2025
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Why is it so easy to hear individual words in your native language, but in a foreign language they run together in one long stream of sound?
Nov 20, 2025
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