Sardinian village may be a new longevity hotspot
A terracotta-tiled village in the mountains of Sardinia may offer researchers a rare opportunity to uncover the secrets of exceptional longevity.
9 hours ago
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Cigarette smoke may prime lung stem cells for different types of lung cancer
Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately ...
10 hours ago
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Making pediatric cancer more 'visible' boosts immunotherapy response
High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system. While a newer class of targeted immunotherapy drugs has improved survival rates, according ...
11 hours ago
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High blood pressure can accelerate osteoarthritis joint damage via a newly identified hormone pathway
For millions of people, osteoarthritis slowly breaks down the joints, bringing pain, swelling and stiffness that make free movement harder with time. It is largely a condition of age, with 73% of those living with it older ...
Even modest post-infection complications can make expanded vaccine coverage cost-effective, modeling suggests
New modeling led by interdisciplinary scientists at the University of British Columbia (UBC) could help public health officials better factor in the long-term impacts of infectious disease when determining optimal vaccine ...
12 hours ago
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Warm temperatures curb appetite but can still promote weight gain, animal experiments find
Researchers at Pennington Biomedical Research Center have identified a key brain mechanism that connects environmental temperature with appetite and energy balance, offering new insight into how external conditions can shape ...
13 hours ago
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Inflammation may push people with obesity toward easier, often less healthy food choices
Around half of people who are severely overweight have mild inflammation in their bodies. Research by neuroscientist Judith Scholing of the Donders Institute at Radboud University shows that this inflammation can cause people ...
14 hours ago
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One dose of protein-targeting CAR-T cells shrinks solid tumors in preclinical tests
CAR-T cell therapies have fundamentally transformed the treatment of several blood and lymph node cancers. However, their use in solid tumors such as liver, breast or lung cancer has so far been significantly more difficult. ...
14 hours ago
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Rare genetic variants linked to lower cognitive test scores in expanded analysis
The largest genetic study of cognition to date has been published, involving nearly half a million people of European ancestry. This provides a new understanding of the genetic factors that shape cognitive differences and ...
15 hours ago
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No detectable increase in pregnancy risks after GLP-1 exposure around conception, largest review to date finds
Exposure to GLP-1 weight-loss and diabetes drugs around conception is not linked to a clearly detectable increase in adverse outcomes for mothers or babies, according to the largest study of its kind, involving more than ...
15 hours ago
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